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Therapeutic Drug Monitoring of Antiepileptic Drugs
Commonly used conventional antiepileptic drugs for pharmacotherapy in epilepsy are phenytoin, carbamazepine and valproic acid. These drugs have complex pharmacokinetic properties leading to fluctuation in their plasma level at given same therapeutic dose.
Geeta Shakya +3 more
doaj +4 more sources
Therapeutic Drug Monitoring [PDF]
Traditionally, therapeutic drug monitoring has been used for the management of epilepsy, cardiac arrhythmias, asthma and depression. This review provides an update, particularly for the newer clinical applications, and how therapeutic drug monitoring (including use of analytical and interpretation tools) can improve clinical outcomes.Improved drug ...
David, Back, Saye, Khoo, Sara, Gibbons
openaire +4 more sources
Purpose: Currently, managing the public and patients during the COVID-19 pandemic is constituting a health care challenge worldwide. Patient-oriented management is of crucial importance to promote emergency preparedness and response.
Zaiwei Song +25 more
doaj +1 more source
Vancomycin Therapeutic Drug Monitoring [PDF]
Introduction: Vancomycin is effective against gram-positive bacteria including staphylococcus aureus which are resistant to methicillin. Vancomycin has a narrow therapeutic range and is associated with adverse drug reactions related to iv infusion ...
Bhaskar Shenoy +2 more
doaj +1 more source
Objective: High-dose methotrexate (HDMTX) is a mainstay therapeutic agent for the treatment of diverse hematological malignancies, and it plays a significant role in interindividual variability regarding the pharmacokinetics and toxicity.
Zaiwei Song +20 more
doaj +1 more source
Parkinson’s disease (PD) is a progressive, neurodegenerative disorder primarily affecting dopaminergic neuronal systems, with impaired motor function as a consequence.
Urszula Adamiak-Giera +6 more
doaj +1 more source
Total and Unbound Pharmacokinetics of Cefiderocol in Critically Ill Patients
Background: Cefiderocol is a siderophore cephalosporin antibiotic active against Gram-negative bacteria, including extended-spectrum beta-lactamase and carbapenemase-producing strains.
Noël Zahr +11 more
doaj +1 more source
Objective: With increasing numbers of biosimilars entering the market or in the approval pipeline in China, understanding the current awareness and attitudes of biosimilars still remains the first step to promote uptake.
Yang Hu +17 more
doaj +1 more source
Toward therapeutic drug monitoring of citalopram in depression? Insights from a systematic review
BackgroundWithin the framework of individualized psychopharmacotherapy, therapeutic drug monitoring (TDM) has gained increasing relevance. In the absence of high-quality evidence, the TDM of citalopram (CIT) and the recommended therapeutic ranges of the ...
Na Xu +10 more
doaj +1 more source
Objective: Continuous lenalidomide (LEN) therapy is important to achieve a therapeutic effect in patients with multiple myeloma (MM) and non-Hodgkin lymphoma (NHL).
Zaiwei Song +18 more
doaj +1 more source

