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Overview of Therapeutic Drug Monitoring [PDF]
The Korean journal of internal medicine, 2009 Therapeutic drug monitoring (TDM) is the clinical practice of measuring specific drugs at designated intervals to maintain a constant concentration in a patient's bloodstream, thereby optimizing individual dosage regimens. It is unnecessary to employ TDM for the majority of medications, and it is used mainly for monitoring drugs with narrow therapeutic
Min Ho Lee, Ju Seop Kang
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Therapeutic Drug Monitoring [PDF]
Journal of the International Association of Physicians in AIDS Care, 2002 Traditionally, therapeutic drug monitoring has been used for the management of epilepsy, cardiac arrhythmias, asthma and depression. This review provides an update, particularly for the newer clinical applications, and how therapeutic drug monitoring (including use of analytical and interpretation tools) can improve clinical outcomes.Improved drug ...
David, Back, Saye, Khoo, Sara, Gibbons
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Therapeutic drug monitoring in drug overdose [PDF]
British Journal of Clinical Pharmacology, 1999 The treatment of poisoned patients is still largely defined by history, clinical assessment and interpretation of ancillary investigations. Measurement of drug concentrations is clinically important for relatively few compounds. Most measurements form an adjunct to and should not be considered a substitute for clinical assessment.
Ian M Whyte, Andrew H. Dawson
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Therapeutic drug monitoring: antiarrhythmic drugs [PDF]
British Journal of Clinical Pharmacology, 1998 Antiarrhythmic agents are traditionally classified according to Vaughan Williams into four classes of action. Class I antiarrhythmic agents include most of the drugs traditionally thought of as antiarrhythmics, and have as a common action, blockade of the fast‐inward sodium channel on myocardium. These agents have a very significant toxicity, and while
T. J. Campbell, K. M. Williams
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On-Site Therapeutic Drug Monitoring [PDF]
Trends in Biotechnology, 2020 Recent technological advances have stimulated efforts to bring personalized medicine into practice. Yet, traditional application fields like therapeutic drug monitoring (TDM) have remained rather under-appreciated. Owing to clear dose-response relationships, TDM could improve patient outcomes and reduce healthcare costs.
H. Ceren Ates +7 more
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YAKUGAKU ZASSHI, 2007 AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Tadaaki, Ito +5 more
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Individualized immunosuppression in transplant patients: potential role of pharmacogenetics. [PDF]
, 2012 The immunosuppressive drugs used to prevent the rejection of transplanted organs have a narrow therapeutic index. Under treatment results in episodes of rejection leading to either damage or loss of the organ. Over immunosuppression increases the risk of
Abboudi, H, Macphee, IA
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Therapeutic drug monitoring – antiepileptic drugs [PDF]
British Journal of Clinical Pharmacology, 1998 Aims To provide a brief critical review of the basis and contemporary practice of monitoring the concentrations of antiepileptic drugs in biological fluids. Methods The review is based on literature data and observations from clinical practice.
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Therapeutic Drug Monitoring and Methods of Quantitation for Carbamazepine [PDF]
, 2017 Carbamazepine is an early anticonvulsant still used today in the treatment of several forms of epilepsy. An active metabolite in the human body contributes to its pharmacological effect.
Ana Vlasceanu +7 more
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Bayesian data assimilation to support informed decision-making in individualized chemotherapy [PDF]
, 2020 An essential component of therapeutic drug/biomarker monitoring (TDM) is to combine patient data with prior knowledge for model-based predictions of therapy outcomes.
de Wiljes, Jana +4 more
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