Results 11 to 20 of about 1,046,320 (355)
Purpose: Currently, managing the public and patients during the COVID-19 pandemic is constituting a health care challenge worldwide. Patient-oriented management is of crucial importance to promote emergency preparedness and response.
Zaiwei Song+25 more
doaj +1 more source
Therapeutic Drug Monitoring [PDF]
Traditionally, therapeutic drug monitoring has been used for the management of epilepsy, cardiac arrhythmias, asthma and depression. This review provides an update, particularly for the newer clinical applications, and how therapeutic drug monitoring (including use of analytical and interpretation tools) can improve clinical outcomes.Improved drug ...
David, Back, Saye, Khoo, Sara, Gibbons
openaire +4 more sources
Objective: High-dose methotrexate (HDMTX) is a mainstay therapeutic agent for the treatment of diverse hematological malignancies, and it plays a significant role in interindividual variability regarding the pharmacokinetics and toxicity.
Zaiwei Song+20 more
doaj +1 more source
Parkinson’s disease (PD) is a progressive, neurodegenerative disorder primarily affecting dopaminergic neuronal systems, with impaired motor function as a consequence.
Urszula Adamiak-Giera+6 more
doaj +1 more source
Objective: With increasing numbers of biosimilars entering the market or in the approval pipeline in China, understanding the current awareness and attitudes of biosimilars still remains the first step to promote uptake.
Yang Hu+17 more
doaj +1 more source
When mycophenolic acid (MPA) was originally marketed for immunosuppressive therapy, fixed doses were recommended by the manufacturer. Awareness of the potential for a more personalized dosing has led to development of methods to estimate MPA area under ...
S. Bergan+37 more
semanticscholar +1 more source
Total and Unbound Pharmacokinetics of Cefiderocol in Critically Ill Patients
Background: Cefiderocol is a siderophore cephalosporin antibiotic active against Gram-negative bacteria, including extended-spectrum beta-lactamase and carbapenemase-producing strains.
Noël Zahr+11 more
doaj +1 more source
Background: To promote model-informed precision dosing (MIPD) for vancomycin (VCM), we developed statements for therapeutic drug monitoring (TDM). Methods: Ten clinical questions were selected.
Kazuaki Matsumoto+11 more
semanticscholar +1 more source
: Nirmatrelvir/ritonavir (Paxlovid) consists of a peptidomimetic inhibitor (nirmatrelvir) of the SARS-CoV-2 main protease and a pharmacokinetic enhancer (ritonavir). It is approved for the treatment of mild-to-moderate COVID-19.
F. Lemaitre+16 more
semanticscholar +1 more source
Toward therapeutic drug monitoring of citalopram in depression? Insights from a systematic review
BackgroundWithin the framework of individualized psychopharmacotherapy, therapeutic drug monitoring (TDM) has gained increasing relevance. In the absence of high-quality evidence, the TDM of citalopram (CIT) and the recommended therapeutic ranges of the ...
Na Xu+10 more
doaj +1 more source