Results 41 to 50 of about 1,376,471 (276)
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Tadaaki, Ito+5 more
openaire +3 more sources
Everolimus dosing recommendations for tuberous sclerosis complex–associated refractory seizures [PDF]
ObjectiveThe present analysis examined the exposure-response relationship by means of the predose everolimus concentration (C-min) and the seizure response in patients with tuberous sclerosis complex-associated seizures in the EXIST-3 study ...
Brandt, Christian+12 more
core +2 more sources
Therapeutic Drug Monitoring of Ganciclovir: Where Are We?
Background: Ganciclovir is the mainstay of therapy for the prophylaxis and treatment of Cytomegalovirus. However, therapy with this antiviral agent is hindered by side effects such as myelosuppression, which often leads to therapy cessation. Underdosing,
A. Märtson+6 more
semanticscholar +1 more source
Immunsuppressiva-Medikamentenspiegelmessung – reine Routine? / Immunosuppressant drug monitoring – a routine undertaking? [PDF]
The quantitative assessment of immunosuppressant drug levels is still one of the most challenging therapeutic drug monitoring procedures in clinical routine. During the past years, several technical developments matured to useable methods. In addition to
Seger, Christoph, Vogeser, Michael
core +1 more source
Therapeutic Drug Monitoring and Methods of Quantitation for Carbamazepine [PDF]
Carbamazepine is an early anticonvulsant still used today in the treatment of several forms of epilepsy. An active metabolite in the human body contributes to its pharmacological effect.
Ana Vlasceanu+7 more
core +4 more sources
Therapeutic Drug Monitoring of Tacrolimus-Personalized Therapy: Second Consensus Report
: Ten years ago, a consensus report on the optimization of tacrolimus was published in this journal. In 2017, the Immunosuppressive Drugs Scientific Committee of the International Association of Therapeutic Drug Monitoring and Clinical Toxicity (IATDMCT)
M. Brunet+36 more
semanticscholar +1 more source
: Individualization of vancomycin dosing based on therapeutic drug monitoring (TDM) data is known to improve patient outcomes compared with fixed or empirical dosing strategies.
S. Reuter+12 more
semanticscholar +1 more source
Phenoconversion and therapeutic drug monitoring [PDF]
Keywords: clobazam; clozapine; genotype–phenotype mismatch; personalized medicine; pharmacogenetics; risperidone; therapeutic drug monitoring ...
Jose de Leon, Jose de Leon, Jose de Leon
openaire +3 more sources
Meropenem use and therapeutic drug monitoring in clinical practice: a literature review
Meropenem, a carbapenem antibiotic, is widely prescribed for the treatment of life‐threatening infections. The main parameter associated with its therapeutic success is the percentage of time that the levels remain above the minimum inhibitory ...
N. A. Steffens+3 more
semanticscholar +1 more source
Background Analgosedation is a cornerstone therapy for mechanically ventilated patients in intensive care units (ICU). To avoid inadequate sedation and its complications, monitoring of analgosedation is of great importance.
Richard J. Nies+9 more
doaj +1 more source