Results 41 to 50 of about 1,472,669 (399)

Expert consensus statement on therapeutic drug monitoring and individualization of linezolid

Frontiers in Public Health, 2022
Linezolid is an oxazolidinone antibacterial drug, and its therapeutic drug monitoring and individualized treatment have been challenged since its approval.
B. Lin, Yangmin Hu, P. Xu, Tao Xu, Chunyan Chen, Lei He, Mi Zhou, Z. Chen, Chunhong Zhang, Xuben Yu, L. Fang, Junfeng Zhu, Y. Ji, Qun Lin, He-qiong Cao, You-Jun Dai, Xiaoyan Lu, Changcheng Shi, Li Li, Changjiang Wang, Xumei Li, Qi Fang, Jing Miao, Zhengyi Zhu, Guangyong Lin, Haichao Zhan, Shiwen Lv, Yalan Zhu, Xin-jun Cai, Yinqing Ying, Meng Chen, Qiong Xu, Yiwen Zhang, Yubin Xu, Pea Federico, Saiping Jiang, Haibin Dai   +36 more
semanticscholar   +1 more source

Everolimus dosing recommendations for tuberous sclerosis complex–associated refractory seizures [PDF]

, 2018
ObjectiveThe present analysis examined the exposure-response relationship by means of the predose everolimus concentration (C-min) and the seizure response in patients with tuberous sclerosis complex-associated seizures in the EXIST-3 study ...
Brandt, Christian, Cheung, Wing, Coello, Neva, Franz, David N, French, Jacqueline A, Grosch, Kai, Kohrman, Michael H, Lawson, John A, Milh, Mathieu, Voi, Maurizio, Wiemer-Kruel, Adelheid, Wong, Michael, Yapici, Zuhal   +12 more
core   +2 more sources

Two cases of a pharmacokinetic interaction between (val)acyclovir and mycophenolate mofetil

Clinical Infection in Practice, 2023
Background: Administration of (val)acyclovir in combination with mycophenolate mofetil (MMF) can result in increased acyclovir plasma levels due to competition with acyclovir for renal tubular secretion.
F.A. Berger, J.E. Nagtegaal, M.M. Malingré   +2 more
doaj   +1 more source

Therapeutic Drug Monitoring of Tacrolimus-Personalized Therapy: Second Consensus Report

Therapeutic Drug Monitoring, 2019
: Ten years ago, a consensus report on the optimization of tacrolimus was published in this journal. In 2017, the Immunosuppressive Drugs Scientific Committee of the International Association of Therapeutic Drug Monitoring and Clinical Toxicity (IATDMCT)
M. Brunet, T. van Gelder, A. Åsberg, V. Haufroid, D. Hesselink, L. Langman, F. Lemaitre, P. Marquet, C. Seger, M. Shipkova, A. Vinks, P. Wallemacq, E. Wieland, J. Woillard, M. Barten, K. Budde, H. Colom, M. Dieterlen, L. Elens, K. Johnson-Davis, P. Kunicki, I. Macphee, S. Masuda, B. Mathew, O. Millán, T. Mizuno, D. Moes, C. Monchaud, Ofelia Noceti, T. Pawiński, N. Picard, R. V. van Schaik, C. Sommerer, N. T. Vethe, B. D. de Winter, U. Christians, S. Bergan   +36 more
semanticscholar   +1 more source

Therapeutic Drug Monitoring of the Echinocandin Antifungal Agents: Is There a Role in Clinical Practice? A Position Statement of the Anti-Infective Drugs Committee of the International Association of Therapeutic Drug Monitoring and Clinical Toxicology

Therapeutic Drug Monitoring, 2021
Purpose: Reduced exposure to echinocandins has been reported in specific patient populations, such as critically ill patients; however, fixed dosing strategies are still used.
H. Kim, S. Baldelli, A. Märtson, S. Stocker, J. Alffenaar, D. Cattaneo, D. Marriott   +6 more
semanticscholar   +1 more source

Voriconazole Therapeutic Drug Monitoring [PDF]

Journal of the Pediatric Infectious Diseases Society, 2014
A 2-year-old boy being treated for acute lymphoblastic leukemia developed confusion and was found to have a mass on cranial imaging. A neurosurgical biopsy revealed an aspergilloma. Intravenous (iv) voriconazole is administered at 8 mg/kg per dose twice daily.
Zachary, Hoy, Elizabeth S, Dodds Ashley, Geoffrey A, Weinberg, Damian J, Krysan   +3 more
openaire   +2 more sources

Immunsuppressiva-Medikamentenspiegelmessung – reine Routine? / Immunosuppressant drug monitoring – a routine undertaking? [PDF]

, 2010
The quantitative assessment of immunosuppressant drug levels is still one of the most challenging therapeutic drug monitoring procedures in clinical routine. During the past years, several technical developments matured to useable methods. In addition to
Seger, Christoph, Vogeser, Michael
core   +1 more source

Microneedle Aptamer-Based Sensors for Continuous, Real-Time Therapeutic Drug Monitoring

Analytical Chemistry, 2022
The ability to continuously monitor the concentration of specific molecules in the body is a long-sought goal of biomedical research. For this purpose, interstitial fluid (ISF) was proposed as the ideal target biofluid because its composition can rapidly
Yao Wu, Farshad Tehrani, H. Teymourian, John Mack, Alexander Shaver, Maria Reynoso, Jonathan Kavner, Nickey Huang, Allison Furmidge, Andrés Duvvuri, Yuhang Nie, Lori M Laffel, Francis J. Doyle, M. Patti, Eyal Dassau, Joseph Wang, N. Arroyo‐Currás   +16 more
semanticscholar   +1 more source

Multimodality imaging in vivo for preclinical assessment of tumor-targeted doxorubicin nanoparticles. [PDF]

, 2012
This study presents a new multimodal imaging approach that includes high-frequency ultrasound, fluorescence intensity, confocal, and spectral imaging to improve the preclinical evaluation of new therapeutics in vivo.
Chu, David, Farkas, Daniel L, Hwang, Jae Youn, Kang, Bong Jin, Lubow, David J, Medina-Kauwe, Lali K, Park, Jinhyoung, Shung, K Kirk   +7 more
core   +7 more sources

Therapeutic drug monitoring – antiepileptic drugs [PDF]

British Journal of Clinical Pharmacology, 1998
Aims  To provide a brief critical review of the basis and contemporary practice of monitoring the concentrations of antiepileptic drugs in biological fluids. Methods  The review is based on literature data and observations from clinical practice.
openaire   +7 more sources