The Ah receptor: adaptive metabolism, ligand diversity, and the xenokine model [PDF]
Author Posting. © American Chemical Society, 2020. This is an open access article published under an ACS AuthorChoice License. The definitive version was published in Chemical Research in Toxicology, 33(4), (2020): 860-879, doi:10.1021/acs.chemrestox ...
Avilla, Mele N. +4 more
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Therapeutic equivalence of inhaled salbutamol [PDF]
The meta-analysis by Hughes et al was hindered by difficulties in comparing trials that were often flawed and of varied design.1 The authors correctly pointed out that, in most of the studies, the use of equivalence as the null hypothesis was invalid. In addition, all but two of the studies looked at the bronchodilator effects in the presence of basal ...
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Toward understanding ambulatory activity decline in Parkinson disease [PDF]
BACKGROUND: Declining ambulatory activity represents an important facet of disablement in Parkinson disease (PD). OBJECTIVE: The primary study aim was to compare the 2-year trajectory of ambulatory activity decline with concurrently evolving facets of ...
Cavanaugh, James T. +5 more
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The Flaws and Future of Islet Volume Measurements
When working with isolated islet preparations, measuring the volume of tissue is not a trivial matter. Islets come in a large range of sizes and are often contaminated with exocrine tissue.
Han-Hung Huang +2 more
doaj +1 more source
Rest tremor in Parkinson's disease: body distribution and time of appearance [PDF]
Objective To assess body distribution and timing of appearance of rest tremor in Parkinson's disease. Methods Information was obtained by a computerized database containing historical information collected at the first visit and data collected during the
Custodero, Giacomo Emanuele +8 more
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Neuroimaging and psychophysiological investigation of the link between anxiety, enhanced affective reactivity and interoception in people with joint hypermobility [PDF]
Objective: Anxiety is associated with increased physiological reactivity and also increased “interoceptive” sensitivity to such changes in internal bodily arousal.
Adolphs +37 more
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Risks for public health related to the presence of tetrodotoxin (TTX) and TTX analogues in marine bivalves and gastropods [PDF]
Peer reviewedPublisher ...
EFSA Panel on Contaminants in the Food Chain (CONTAM)
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Background: The potency of intravenous bumetanide to furosemide using a ratio of 1:40 has been suggested; however, there are little data supporting this ratio.
Nappi JM
doaj
Beyond Concurrent Chemoradiation: The Emerging Role of PD-1/PD-L1 Inhibitors in Stage III Lung Cancer. [PDF]
Concurrent chemoradiation (cCRT) with platinum-based chemotherapy is standard-of-care therapy for patients with stage III unresectable non-small cell lung cancer (NSCLC).
Dicker, Adam P., Lu, Bo, McCall, Neal S.
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Bioequivalence and therapeutic equivalence of psychotropic drugs
Introduction to the market of generic drugs has increased access to modern therapies and enabled significant reduction of their cost, leading to containment of public expenditures on drug reimbursement. The assessment of bioequivalence of reference and generic drugs is based on the assumption that two different drug products are equivalent when their ...
K. Rokita, E. Balkowiec-Iskra, G. Cessak
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