Results 181 to 190 of about 1,123,683 (262)

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Generative AI Mental Health Chatbots as Therapeutic Tools: Systematic Review and Meta-Analysis of Their Role in Reducing Mental Health Issues. [PDF]

J Med Internet Res
Zhang Q, Zhang R, Xiong Y, Sui Y, Tong C, Lin FH.   +5 more
europepmc   +1 more source

Extracellular Vesicles as Therapeutic Tools for the Treatment of Chronic Wounds. [PDF]

Pharmaceutics, 2021
Bray ER, Oropallo AR, Grande DA, Kirsner RS, Badiavas EV.   +4 more
europepmc   +1 more source

Discourse Analysis

, 2016
This chapter (a) presents discourse analysis as both epistemology and methodology; (b) suggests a sociolinguistic toolkit that could be used as one type of approach to conducting discourse analysis; (c) reviews and points to literature in music education
Talbot, Brent C.
core  

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Repurposing alternative splicing events as potential targets for the design of diagnostic and therapeutic tools in PCa. [PDF]

Front Oncol
Martínez-Montiel N, Vite-Arciniega JJ, Rosas-Murrieta NH, Martínez-Contreras RD.   +3 more
europepmc   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Apolipoprotein and LRP1-Based Peptides as New Therapeutic Tools in Atherosclerosis. [PDF]

J Clin Med, 2021
Benitez Amaro A, Solanelles Curco A, Garcia E, Julve J, Rives J, Benitez S, Llorente Cortes V.   +6 more
europepmc   +1 more source

Macrophages in graft-versus-host disease (GVHD): dual roles as therapeutic tools and targets. [PDF]

Clin Exp Med
Raoufi A, Soleimani Samarkhazan H, Nouri S, Khaksari MN, Abbasi Sourki P, Sargazi Aval O, Baradaran B, Aghaei M.   +7 more
europepmc   +1 more source

New Diagnostic and Therapeutic Tools for Thyroid Cancer

International Journal of Endocrinology, 2013
Eleonore Fröhlich, Richard Wahl, Barbara Czarnocka, Leonidas Duntas   +3 more
doaj   +1 more source