Results 41 to 50 of about 1,123,683 (262)

Protein kinase a distribution differentiates human glioblastoma from brain tissue [PDF]

open access: yes, 2017
Brain tumor glioblastoma has no clear molecular signature and there is no effective therapy. In rodents, the intracellular distribution of the cyclic AMP (cAMP)-dependent protein kinase (Protein kinase A, PKA) R2Alpha subunit was previously shown to ...
Caretta, Antonio   +3 more
core   +2 more sources

Tetracyclines - An Important Therapeutic Tool for Dermatologist

open access: yesInternational Journal of Environmental Research and Public Health, 2022
Tetracyclines are a group of antibiotics whose first representative was discovered over 70 years ago. Since then, they have been of great interest in dermatology. In addition to their antibacterial activity, they are able to inhibit metalloproteinases and exhibit anti-inflammatory, anti-apoptotic and antioxidant effects.
Malgorzata Orylska-Ratynska   +2 more
openaire   +2 more sources

MicroRNA biomarkers as next-generation diagnostic tools for neurodegenerative diseases: a comprehensive review

open access: yesFrontiers in Molecular Neuroscience
Neurodegenerative diseases (NDs) are characterized by abnormalities within neurons of the brain or spinal cord that gradually lose function, eventually leading to cell death.
Hafiz Muhammad Husnain Azam   +15 more
doaj   +1 more source

Phytochemical screening and inhibitory activity of oxalocalcic crystallization of Arbutus unedo L. leaves

open access: yesHeliyon, 2018
The present study is focused on the experimental verification of the efficiency of Arbutus unedo L. leaves against the crystallization of calcium oxalate.
Rabie Kachkoul   +5 more
doaj   +1 more source

Dogs as Therapeutic Partners, Not Therapeutic Tools: Ethical Considerations for AAT in the Correctional Setting

open access: yesSocial Sciences, 2021
Although the benefits of animal assisted therapy for people are well established, the ethical considerations for the welfare and safety of the non-human animals involved are not.
Kimberly Collica-Cox, George J. Day
doaj   +1 more source

Endoscopic scores for inflammatory bowel disease in the era of 'mucosal healing'. old problem, new perspectives [PDF]

open access: yes, 2016
The importance of the endoscopic evaluation in inflammatory bowel disease (IBD) management has been recognized for many years. However, the modalities for reporting endoscopic activity represent an ongoing challenge.
Corleto, Vito Domenico   +5 more
core   +1 more source

Enfermedad renal crónica: de cómo políticas públicas se transforman en herramientas terapéuticas eficaces en la práctica clínica.

open access: yesARS Medica, 2023
Las enfermedades crónicas no transmisibles son las principales causas de días de actividad laboral perdidos, deterioro de calidad de vida y mortalidad en Chile y el mundo.
Fernando González Fuenzalida
doaj   +1 more source

Clinical consequences of antibody formation, serum concentrations, and HLA-Cw6 status in psoriasis patients on Ustekinumab [PDF]

open access: yes, 2019
Background: Ustekinumab for the treatment of psoriasis is currently administered in a standard dosing regimen. However, some patients tend to benefit from alternative dosing regimens, a step toward personalized medicine.
Busard, Celine, I   +9 more
core   +1 more source

CRISPR/Cas9‐mediated genome editing: from basic research to translational medicine [PDF]

open access: yes, 2020
The recent development of the CRISPR/Cas9 system as an efficient and accessible programmable genome-editing tool has revolutionized basic science research. CRISPR/Cas9 system-based technologies have armed researchers with new powerful tools to unveil the
Ferreira, B I   +2 more
core   +1 more source

Probiotics: Nutritional Therapeutic Tool

open access: yesJournal of Probiotics & Health, 2018
The advent of various health care policies and digital revolution has fuelled interest in the direction of food supplements, and as preventive or curative drug containing live non-pathogenic bacteria, probiotics. The widespread usage of probiotics by consumers and in clinical practice has emphatically made to understand the benefits associated with ...
Shailendra Raghuwanshi   +3 more
openaire   +1 more source

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