Results 101 to 110 of about 1,969,671 (301)

The Salmonella Paratyphi A O-Antigen Glycoconjugate Vaccine Is Able to Induce Antibodies with Bactericidal Activity Against a Panel of Clinical Isolates

Vaccines
Background: Typhoid and paratyphoid fevers represent a global health burden, especially in Southern Asia, exacerbated by the increase in antimicrobial resistance.
Marika Pinto, Salvatore Durante, Martina Carducci, Luisa Massai, Renzo Alfini, Elli Mylona, Abhilasha Karkey, Stephen Baker, Francesca Micoli, Carlo Giannelli, Omar Rossi, Simona Rondini   +11 more
doaj   +1 more source

Inflammation Unchecked: Concurrent Kawasaki Disease and Stevens‐Johnson Syndrome in an 18‐Month‐Old Child

Arthritis Care &Research, EarlyView.
Catherine Deffendall, Jodi Backalar, Elizabeth Acevedo Zapata, Adriana Della Porta, Lorin Bibb, Tyler Reese, Charlotte M. Brown   +6 more
wiley   +1 more source

Aptamer‐Engineered Liposomal Platform Enables in Situ cDC1 Vaccination to Potentiate Immunotherapy in Prostate Cancer

Advanced Science, EarlyView.
Prostate cancer is immunologically ‘cold’, with scarce, dysfunctional type 1 conventional dendritic cells (cDC1s) that limit T cell priming. We introduce an aptamer‐targeted liposomedelivering FMS‐like tyrosine kinase 3 ligand (Flt3L) and chlorin e6 (Ce6). Ultrasound induces antigen release and cDC1s recruitment, creating an in situ cDC1 vaccine.
Jiayi Wang, Xuan Wang, Xinfeng Dai, Linxin Tian, Wencheng Shen, Xueliang Liu, Wei Xue, Jiahua Pan, Yu Yang   +8 more
wiley   +1 more source

GMMA-based vaccine candidates against invasive nontyphoidal salmonellosis elicit bactericidal antibodies against a panel of epidemiologically relevant Salmonellae

Frontiers in Immunology
Systemic disease caused by nontyphoidal Salmonella (NTS) represents a major cause of death and morbidity, especially in young children in sub-Saharan Africa.
Daniele De Simone, Marika Pinto, Maria Grazia Aruta, Marta Benincasa, Martina Carducci, Roberta Di Benedetto, Francesco Citiulo, Miren Iturriza, Elli Mylona, Stephen Baker, Mariagrazia Pizza, Carlo Giannelli, Francesca Mancini, Rocío Canals, Omar Rossi   +14 more
doaj   +1 more source

Prophylactic and therapeutic vaccines for obesity

Clinical and Experimental Vaccine Research, 2014
Chronic diseases such as obesity and diabetes are major causes of death and disability throughout the world. Many causes are known to trigger these chronic diseases, and infectious agents such as viruses are also pathological factors. In particular, it is considered that adenovirus 36 infections may be associated with obesity.
Na, Ha-Na, Kim, Hun, Nam, Jae-Hwan
openaire   +2 more sources

Research and Development on Therapeutic Agents and Vaccines for COVID-19 and Related Human Coronavirus Diseases

, 2020
Research and Development on Therapeutic Agents and Vaccines for COVID-19 and Related Human Coronavirus ...
Jeffrey Smoot (8565084), Anne C. Gregg (8565087), Angela D. Daniels (8565090), Steve P. Watkins (8565078), Linda J. Carter (8565081), Linda V. Garner (8565075), Cynthia Liu (1337823), Qiongqiong Zhou (92521), Yingzhu Li (8565072), Susan Jervey (8565093), Dana Albaiu (8565096)   +10 more
core   +1 more source

Engineering Microbial Particles for Next‐Generation Biomedical Platforms

Advanced Science, EarlyView.
Microbe‐derived particles (MDPs), which include extracellular vesicles, outer membrane vesicles, inclusion bodies, polysaccharide particles, and virus‐like particles, represent a rapidly expanding category of bioinspired nanomaterials. With their natural origin, intrinsic biocompatibility, and highly programmable functionality, MDPs serve as a ...
Yuting Li, Yunjie Lu, Ziyan Huang, Jianjiang Chen, Yanbin Liu, Lei Qin, Chao Wang, Yumin Wu   +7 more
wiley   +1 more source

RESULTS OF A PILOT CLINICAL TRIAL OF DENDRITICCELL BASED VACCINES FOR TREATMENT OF RECURRENT HERPESVIRUS INFECTION

Медицинская иммунология, 2016
Chronic recurrent infections caused by herpes simplex virus (HSV) types 1 and 2 represent a serious medical and social challenge. Given an important role of immune system in surveillance of viral infections, an induced enhancement of antigen-specific ...
O. Yu. Leplina, N. M. Starostina, D. D. Blinova, O. I. Zheltova, E. A. Oleinik, T. V. Tyrinova, A. A. Ostanin, E. R. Chernykh   +7 more
doaj   +1 more source

Research and Clinical Progress of Therapeutic Tumor Vaccines

Therapeutic cancer vaccines are a new growth point of biomedicine with broad industrial prospects in the post-COVID-19 era. Many large international pharmaceutical companies and emerging biotechnology companies are deploying different tumor therapeutic ...
Sihan Liu, Wei, Dexian, Liang, Jinghui, Zhang, Yu, Yu Zhang, He, Qing, Linyu Zhang, Liu, Sihan, Wang, Junzhi, Dejiang Tan, Sun, Huimin, Zhuang Li, Jinghui Liang, Junzhi Wang, Qing He, Zheng, Yiyang, Zhang, Linyu, Tan, Dejiang, Yiyang Zheng, Huimin Sun, Li, Zhuang, Dexian Wei, Dong, Chunyan, Chunyan Dong   +23 more
core   +1 more source

Nanomaterials for Allergy Diagnosis and Treatment: Advances, Opportunities and Translational Challenges

Advanced Science, EarlyView.
Nanomaterials offer dual applications in allergy management. For diagnosis, nanomaterials enhance analytical sensitivity and improve detection in specific IgE and functional assays such as the basophil activation test (BAT). For allergen‐specific immunotherapy, nanomaterials enable allergen masking and controlled release, and effectively modulate the ...
Madiha Habib, Shan Jiang, Joyce ZX Lee, CW Lim, HL Yeung, Nicki YH Leung, Patrick SC Leung, Ting F Leung, Christine YY Wai   +8 more
wiley   +1 more source