Results 81 to 90 of about 1,969,671 (301)

Have Diagnostics, Therapies, and Vaccines Made the Difference in the Pandemic Evolution of COVID-19 in Comparison with “Spanish Flu”?

, 2023
In 1918 many countries, but not Spain, were fighting World War I. Spanish press could report about the diffusion and severity of a new infection without censorship for the first-time, so that this pandemic is commonly defined as “Spanish flu”,
Riccardo De Santis, Roberto Nisini, Roberto Biselli, Raffaele D’Amelio, Mario Stefano Peragallo, Sabrina Mariotti, Florigio Lista   +6 more
core   +1 more source

Mapping the Social Network Structure and Composition of Black Individuals With Rheumatic and Musculoskeletal Conditions

Arthritis Care &Research, EarlyView.
Objective Our objective was to describe the social networks of Black individuals with rheumatic and musculoskeletal conditions and understand the clustering of health‐related behaviors to inform future community‐based, peer‐led interventions. Methods We used an adapted Personal Network Survey for Clinical Research (PERSNET) to map the personal social ...
Taussia Boadi, Amar Dhand, Leah Santacroce, Neil Pillai, Komel Safdar, Mia T. Chandler, Ariel Childs, Monica Crespo‐Bosque, Gina Curry, Mary Dollear, Alice Eggleston, Daniel Erickson, Dieufort Fleurissaint, Denice Garrett, Gail Granville, Tyler Green, Magdalena Hamielec, Elena Losina, Karen Mancera‐Cuevas, Mary Ann Nelson, Chisa Nosamiefan, Bisola Ojikutu, Tonya S. Roberson, Mary Beth Son, Marie Jacques Toussaint, Michael York, Rosalind Ramsey‐Goldman, Candace H. Feldman   +27 more
wiley   +1 more source

A Holistic Platform Approach for Developing Robust Pulmonary mRNA Delivery: Integrating Novel Phenolic Acid‐Derived Ionizable Lipids and Device Engineering

Advanced Functional Materials, EarlyView.
An integrated pulmonary mRNA delivery platform combining novel biodegradable syringic acid‐derived ionizable lipids, design‐of‐experiments formulation optimization, and vibrating‐mesh nebulizer engineering enabled stable aerosolization and efficient lung delivery.
Neha Kaushal, Younan Ma, Asad Khanmohammed, Dipen Parande, Hanming Zhang, Saket Dolare, Juliet Chen, Apiwat Wangweerawong, Saswata Karmakar, Hongfeng Deng, Frank Koppenhagen, Shraddha Sharma, Eric Reyes, Sherry He, Lianne Boeglin, Caroline Woo, Azadeh Paksa, Ayed Allawzi, Anusha Dias, Gregory Troiano, Shrirang Karve, Frank DeRosa   +21 more
wiley   +1 more source

Targeting immune response with therapeutic vaccines in premalignant lesions and cervical cancer: hope or reality from clinical studies [PDF]

, 2016
Human papillomavirus (HPV) is widely known as a cause of cervical cancer (CC) and cervical intraepithelial neoplasia (CIN). HPVs related to cancer express two main oncogenes, i.e.
Pizzuti, L, Zampa, G, Barba, M, Vizza, E, Paolini, F, Michelotti, A, Curzio, G, Sanguineti, G, Sergi, D, Gamucci, T., Corrado, G, Venuti, A, Mariani, L, MARCHETTI, PAOLO, Di Filippo, S, Santini, D, De Maria, R, Gamucci, T, Giordano, Antonio|, Marchetti, P, Vici, P, Sergi, D., Maugeri-Saccà, M, Natoli, C, Tomao, F, Di Lauro, L, De Maria Marchiano, R., TOMAO, FEDERICA, Venuti, A., Maugeri Saccà, M, Giordano, A, Marchetti P., Paolini F., Natoli C., Gamucci T., Barba M., Sergi D., Tomao F., Mariani L., Zampa G., Michelotti A., Pizzuti L., Sanguineti G., NATOLI, Clara, Vici P., Di Filippo S., Vizza E., Giordano A., Di Lauro L., Curzio G., Santini D., Corrado G., Venuti A., Maugeri-Sacca M., De Maria R.   +54 more
core   +1 more source

Engineering Antigen Density on M13 Bacteriophage for Personalized Nanovaccine

Advanced Healthcare Materials, EarlyView.
Increasing antigen density on the phage capsid impacts phage uptake and antigen cross‐presentation by antigen‐presenting cells, leading to enhanced activation of antitumor CD8+ T cells in the draining lymph nodes. These activated CD8+ T cells subsequently recognize the antigen‐expressing tumors and mediate their specific cytotoxic killing, thereby ...
Shengnan Huang, Allison Madow, Jack Rudrum, Huaiyao Peng, Hao Nghi Luu, Peiyan Dong, Jifa Qi, Angela M. Belcher   +7 more
wiley   +1 more source

Outbreak of caterpillars (Lepidoptera) in Valle de Caracas, Venezuela

Scientific Reports
Lepidopterism, a condition resulting from accidents by caterpillars or the adult forms of moths and butterflies, typically manifests as mild and self-limited hypersensitivity reactions.
David A. Forero-Peña, José A. Suárez, Fhabián S. Carrión-Nessi, José E. Piñango, Daniela Restuccia, Jorge E. Homsi-Álcívar, Iván Mendoza, Juan D. Ramírez, Laura Naranjo-Lara, Alberto E. Paniz-Mondolfi   +9 more
doaj   +1 more source

The EPIICAL project: an emerging global collaboration to investigate immunotherapeutic strategies in HIV-infected children

Journal of Virus Eradication, 2015
: Short summary: The EPIICAL (Early-treated Perinatally HIV-infected Individuals: Improving Children's Actual Life with Novel Immunotherapeutic Strategies) project arises from the firm belief that perinatally infected children treated with suppressive ...
P. Palma, C. Foster, P. Rojo, P. Zangari, A. Yates, N. Cotugno, N. Klein, K. Luzuriaga, S. Pahwa, E. Nastouli, D.M. Gibb, W. Borkowsky, S. Bernardi, V. Calvez, E. Manno, Nadia Mora, A. Compagnucci, B. Wahren, M.Á Muñoz-Fernández, A. De Rossi, J. Ananworanich, D. Pillay, C. Giaquinto, P. Rossi   +23 more
doaj   +1 more source

Human papillomavirus vaccines in plants

, 2010
Human papillomaviruses are the etiological agents of cervical cancer, one of the two most prevalent cancers in women in developing countries. Currently available prophylactic vaccines are based on the L1 major capsid protein, which forms virus-like ...
Colomba Giorgi, Edward P Rybicki, Rosella Franconi, Rybicki, E. P., Giorgi, C., Franconi, R.   +5 more
core   +1 more source

Advanced Materials for Biologics Delivery to Brain Tumors

Advanced Materials, EarlyView.
Material innovation is central to unlocking the therapeutic potential of biologics against many central nervous system diseases, including brain cancer. By engineering carriers with controlled transport, targeting, and release properties, advanced materials can overcome the blood–brain barrier and tumor microenvironment, improving the delivery of ...
Yuran Feng, Yuxue Cao, Maria Kavallaris, Taskeen Janjua, Amirali Popat   +4 more
wiley   +1 more source

Programmable Carrier‐Free All‐Enzyme Beads for Modular Continuous‐Flow Biocatalysis

Advanced Materials, EarlyView.
Genetically encoded enzyme building blocks self‐assemble into monodisperse, carrier‐free protein beads via a droplet‐based formulation strategy. These programmable catalytic particles enable modular continuous‐flow biocatalysis, from single‐enzyme reactions to multi‐enzyme cascades and bead–bead coupled reactor systems.
Jennifer Kühne, Julian S. Hertel, André Delavault, Judith Felk, Martin Peng, Lara Reuber, Felix Ott, Kim Wanner, Marc F. Münker, Adrian Neukirch, Alexei Kiselev, Kersten S. Rabe, Christof M. Niemeyer   +12 more
wiley   +1 more source