Results 61 to 70 of about 143,501 (306)

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Pregnancy after thermal balloon ablation

Journal of Obstetrics and Gynaecology, 2011
Endometrial ablation (EA) has been performed for over 20 years as an alternative treatment to hysterectomy in women with menorrhagia.
L, Tripathi, P, Chattopadhyay, M, Annappa, R, Ghani   +3 more
openaire   +2 more sources

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Insufficient ablation promotes the metastasis of residual non-small cell lung cancer (NSCLC) cells via upregulating carboxypeptidase A4

International Journal of Hyperthermia, 2021
Background Thermal ablation is a potentially curative therapy for early-stage non-small cell lung cancer (NSCLC). Early recurrence after thermal ablation necessitates our attention.
Peng Yan, Xiaoli Lyu, Sinian Wang, Suhe Dong, Zheng Zhu, Bo Cheng, Yuping Sun, Qisheng Jiang, Jie Liu, Fengsheng Li   +9 more
doaj   +1 more source

The impact of vaporized nanoemulsions on ultrasound-mediated ablation [PDF]

, 2013
BACKGROUND: The clinical feasibility of using high-intensity focused ultrasound (HIFU) for ablation of solid tumors is limited by the high acoustic pressures and long treatment times required.
Kopechek, Jonathan A., Porter, Tyrone M., Zhang, Peng   +2 more
core   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Efficacy and safety of US-guided thermal ablation for primary hyperparathyroidism: a systematic review and meta-analysis

International Journal of Hyperthermia, 2020
Purpose To summarize the published literature on thermal ablation for primary hyperparathyroidism (PHPT) and to evaluate the effectiveness and safety of thermal ablation as a novel treatment strategy.
Jieyi Ye, Weijun Huang, Guangliang Huang, Yide Qiu, Weiwei Peng, Ninghui Lan, Xiaoyan Xie, Baoxian Liu   +7 more
doaj   +1 more source

Thermal Ablation Versus Wedge Resection for Stage I Non-small Cell Lung Cancer Based on the Eighth Edition of the TNM Classification: A Population Study of the US SEER Database

Frontiers in Oncology, 2020
BackgroundThe incidence rates of early-stage non-small cell lung cancer (NSCLC) are now increasing, and therapies such as thermal ablation have shown potential therapeutic promise. This study aimed to determine the influence of different surgical methods
Chenxi Zeng, Jiawei Lu, Yitao Tian, Xiangning Fu   +3 more
doaj   +1 more source

Image-based computer modeling assessment of microwave ablation for treatment of adrenal tumors

International Journal of Hyperthermia, 2022
Purpose To assess the feasibility of delivering microwave ablation for targeted treatment of aldosterone producing adenomas using image-based computational models.Methods We curated an anonymized dataset of diagnostic 11C-metomidate PET/CT images of 14 ...
Jan Sebek, Grazia Cappiello, George Rahmani, Nooshin Zeinali, Muireann Keating, Michael Fayemiwo, Jim Harkin, Liam McDaid, Bryan Gardiner, Declan Sheppard, Russell Senanayake, Mark Gurnell, Martin O’Halloran, M. Conall Dennedy, Punit Prakash   +14 more
doaj   +1 more source

Multidimensional reaction kinetic ablation program /REKAP/ [PDF]

, 1967
Multidimensional reaction kinetics ablation program provides an improved capability for analyzing thermal performance of partially penetrated charring ablator heat shields. The capability was provided for determining transient temperature histories in an
Aston, B., Binck, E., Collingswood, B.
core   +1 more source