Results 71 to 80 of about 3,136 (218)

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

FEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas, Aaron D. Morgan, Ignas Čiurlionis, Christian Böhm, Stefan Jockenhövel, Willi Jahnen‐Dechent, Marc A. M. J. van Zandvoort   +6 more
wiley   +1 more source

Diagnosis of recurrent reflux within the remnant non-treatment stump after bilateral cyanoacrylate ablation of the great saphenous veins

SAGE Open Medical Case Reports, 2019
Cyanoacrylate ablation, along with mechanochemical ablation, is one of the best-known non-thermal ablation treatment methods for superficial venous reflux.
Seung Joon Park, Su Bin Yim, Dae Won Cha, Sung Chul Kim, Jo Han Rhee   +4 more
doaj   +1 more source

Thermal Ablation [PDF]

Academic Radiology, 2009
Pawel Mertyna, Wallace Goldberg, Wei Yang, S. Nahum Goldberg   +3 more
openaire   +1 more source

Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound

FEBS Open Bio, EarlyView.
We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda, Natsue Maezono, Rina Uchikoshi, Nobuyuki Kato, Masanori Ikeda   +4 more
wiley   +1 more source

Efficacy and safety of percutaneous thermal ablation in Bosniak III and IV cystic renal masses: a systematic review and meta-analysis

Diagnostic and Interventional Radiology
PURPOSE: Local thermal ablation is considered a standard treatment for small kidney masses. However, few studies have investigated the efficacy and safety of thermal ablation for cystic kidney masses.
Hans-Jonas Meyer, Timo Christian Meine, Manuel Florian Struck, Silke Zimmermann   +3 more
doaj   +1 more source

Adenosine triphosphate as a modulator of protein interactions and stability

FEBS Open Bio, EarlyView.
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Research progress in ablative resistant ethylene■propylene■diene terpolymer

Hecheng xiangjiao gongye
Ethylene■propylene■diene terpolymer （EPDM） was a new type of ablation■resistant matrix material with low density, good thermal stability and excellent ablation resistance, and it found extensive applications in aerospace, thermal protection and other ...
ZHAO Dong-wei1, WEN Yan-wei2, FU Quan-sheng1, CHEN Meng-han1, YANG Zi-fan1, JIA Hong-bing1
doaj   +1 more source

Similar complication rates for irreversible electroporation and thermal ablation in patients with hepatocellular tumors

Radiology and Oncology, 2019
To compare the frequency of adverse events of thermal microwave (MWA) and radiofrequency ablation (RFA) with non-thermal irreversible electroporation (IRE) in percutaneous ablation of hepatocellular carcinoma (HCC).
Verloh Niklas, Jensch Isabel, Lürken Lukas, Haimerl Michael, Dollinger Marco, Renner Philipp, Wiggermann Philipp, Werner Jens Martin, Zeman Florian, Stroszczynski Christian, Beyer Lukas Philipp   +10 more
doaj   +1 more source