Results 71 to 80 of about 143,501 (306)
Dynamics and stability of radiation-driven double ablation front structures. [PDF]
, 2010 The dynamics of double ablation front (DAF) structures is studied for planar targets with moderate atomic number ablators. These structures are obtained in hydrodynamic simulations for various materials and laser intensities and are qualitatively ...
Drean, V. +3 more
core +3 more sources
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Expectations for the Deep Impact collision from cometary nuclei modelling [PDF]
, 2005 Using the cometary nucleus model developed by Espinasse et al. (1991), we calculate the thermodynamical evolution of Comet 9P/Tempel 1 over a period of 360 years.
Klinger, Jurgen +3 more
core +6 more sources
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
International Journal of Hyperthermia, 2019 Benign thyroid nodules are a common clinical occurrence and usually do not require treatment unless symptomatic. During the last years, ultrasound-guided minimally invasive treatments (MIT) gained an increasing role in the management of nodules causing ...
Enrico Papini +28 more
doaj +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Debris Thickness of Glaciers in the Everest Area (Nepal Himalaya) Derived from Satellite Imagery Using a Nonlinear Energy Balance Model [PDF]
, 2014 Debris thickness is an important characteristic of debris-covered glaciers in the Everest region of the Himalayas. The debris thickness controls the melt rates of the glaciers, which has large implications for hydrologic models, the glaciers' response to
McKinney, D. C., Rounce, D. R.
core +2 more sources
FEBS Open Bio, EarlyView.dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon +6 more
wiley +1 more source
, 2016 The specific mechanisms which leads to the formation of fractal nanostructures by pulsed laser deposition remain elusive despite intense research efforts, motivated mainly by the technological interest in obtaining tailored nanostructures with simple and
Archetti, D. +5 more
core +1 more source
Sub-debris melt rates on southern Inylchek Glacier, central Tian Shan [PDF]
, 2008 Melt rates of glacier surfaces are strongly influenced by the existence of a debris cover. Dependent on thickness and other physical parameters the debris layer can enhance or reduce ablation as compared to bare ice conditions.
Hagg, Wilfried +3 more
core +2 more sources