Results 101 to 110 of about 2,719,034 (384)

On‐Chip Multiplexed Voltammetry Using a Universal Antifouling Hydrogel and Porous Gold Foam Interface for Stress and Inflammation Monitoring

Advanced Sensor Research, EarlyView.
A multiplexed device is fabricated via silicon microelectronics and adapted for electrochemical sensing interface. Its 100 um gold disk electrodes are modified with porous gold foam and coated with a rapid, biocompatibleantifouling layer. Universal immunoglobulin G (IgG) capture is enabled through Protein A/G.
Vuslat B. Juska, Stacey Hendriks, Esmeralda Santillan‐Urquiza, Nadia Moukri, Pedro Estrela, Graeme D. Maxwell, Bernadette O'Brien, Bernardo Patella, Rosalinda Inguanta, Alan O'Riordan   +9 more
wiley   +1 more source

The Dietary Inclusion of Chickpea Seeds (Cicer Arietinum L.) Influences the Thermal Properties of Muscle Proteins, But Not the Texture of Drumstick Muscle in Broiler Chickens

Brazilian Journal of Poultry Science
In this study, the effect of replacement of soybean meal with raw chickpea seeds as a primary protein source in the diet of broiler chicks on physical properties of drumstick muscle (m. gastrocnemius) was examined.
S Muszyński, E Tomaszewska, M Kwiecień, P Dobrowolski, I Świetlicka, W Tanaś, B Sołowiej, M Ejtel, E Szcześniak, T Tomczyk-Warunek   +9 more
doaj   +1 more source

Stabilisation of Na,K-ATPase structure by the cardiotonic steroid ouabain [PDF]

, 2013
Cardiotonic steroids such as ouabain bind with high affinity to the membrane-bound cation-transporting P-type Na,K-ATPase, leading to complete inhibition of the enzyme.
Abdul-Gader, Andrew J. Miles, B.A. Wallace, Esmann, Esmann, Esmann, Esmann, Fedosova, Kabsch, Kaplan, Klodos, Klose, Lees, Lowry, Mikael Esmann, Miles, Miles, Miles, Miles, Morth, Natalya U. Fedosova, Ogawa, Provencher, Schoner, Shinoda, Skou, Sreerama, Søren V. Hoffmann, Van Stokkum, Whitmore, Yatime   +30 more
core   +1 more source

Silk‐Fibroin as Biocompatible and Bioresorbable Enzyme Immobilization Matrix for Screen‐Printed Amperometric Glucose Biosensors

Advanced Sensor Research, EarlyView.
Silk‐fibroin is applied as an immobilization matrix for a biocompatible and bioresorbable amperometric glucose biosensor. The immobilization matrix is optimized with regard to silk‐fibroin content, enzyme loading, and water solubility. The optimized silk‐fibroin matrix is compared to a BSA/glutaraldehyde‐based matrix.
Kevin A. Janus, Stefan Achtsnicht, Benedetta Isella, Alexander Kopp, Koichiro Miyamoto, Tatsuo Yoshinobu, Michael Keusgen, Michael J. Schöning   +7 more
wiley   +1 more source

Influence of chilled and frozen storage on the stability of trout and herring fillet [PDF]

, 2006
Effects of chilled and frozen storage on specific enthalpy (ΔH) and transition temperature (Td) of protein denaturation as well as on selected functional properties of muscle tissue of rainbow trout and herring were investigated. The Td of myosin shifted
Beyrer, Michael, Rüsch, Mark
core   +2 more sources

Bilirubin Targeting WNK1 to Alleviate NLRP3‐Mediated Neuroinflammation

Advanced Science, EarlyView.
At physiological concentrations, bilirubin binds to the kinase domain of WNK1, thereby augmenting its activity and facilitating the phosphorylation of downstream SPAK/OSR1. This phosphorylation inhibits KCC2 activity, leading to elevate intracellular chloride levels in neurons.
Linfei Mao, Jiayu Lu, Quanjun Yang, Zhenqi Liu, Cuiping Wu, Bingbing Ke, Kaiyan Su, Haolin Yuan, Yaqi Cui, Yao Wang, Richard Salvi, Guang Yang, Shankai Yin, Feng Liu, Chunyan Li   +14 more
wiley   +1 more source

Rational Design of Inner Ear Drug Delivery Systems

Advanced Science, EarlyView.
Hearing loss is a common disease affecting many people, and inner ear lesions are one of the most important causes. This review focuses on the treatment of inner ear hearing loss by drug delivery systems. It includes the current methods and technologies developed, and it predicts possible directions.
Xiayidan Maimaitikelimu, Zhiyan Xuan, Haoyu Ren, Keng Chen, Hui Zhang, Huan Wang   +5 more
wiley   +1 more source

Anharmonic stacking in supercoiled DNA

, 2012
Multistep denaturation in a short circular DNA molecule is analyzed by a mesoscopic Hamiltonian model which accounts for the helicoidal geometry. Computation of melting profiles by the path integral method suggests that stacking anharmonicity stabilizes ...
Bates A D, Feynman R P, Joyeux M, Kleinert H, Marco Zoli, Metzler R, Mukherjee A K, Peyrard M, Peyrard M, Romero-Enrique J M, Tabi C B, Weber G   +11 more
core   +1 more source

Thermal denaturation of nucleosomal core particles

Nucleic Acids Research, 1978
Thermal denaturation of very homogeneous preparations of core particles from chicken erythrocyte chromatin is studied by several techniques. The change in absorbance, which is very closely paralleled by changes in heat capacity, which is very closely paralleled by changes in heat capacity, is a biphasic process with inflexions at 60 degrees C and 74 ...
Kelly Tatchell, Wolfgang O. Weischet, H. Klump, K. E. Van Holde   +3 more
openaire   +4 more sources

Cryptic Splicing of GAP43 mRNA is a Novel Hallmark of TDP‐43‐Associated ALS and AD

Advanced Science, EarlyView.
TDP‐43 dysfunction disrupts RNA processing, inducing cryptic exon 4a1 inclusion in GAP43 and reducing its protein levels. This aberrant splicing impairs axonal regeneration and contributes to neurodegeneration in ALS and AD. RNA‐seq of patient brains reveals GAP43 downregulation and 4a1 upregulation, identifying cryptic exon 4a1 as a potential ...
Mingming Yang, Qi Wang, Dongkun Kang, Shijia Wang, Yanli Jiang, Jian‐Zhi Wang, Chen Ming, Rong Liu, Jianlan Gu, Xiaochuan Wang   +9 more
wiley   +1 more source