Results 121 to 130 of about 1,963,376 (294)

Low-Temperature and High-Efficiency Solid-Phase Amplification Based on Formamide

open access: yesMicromachines
The thermal stability of DNA immobilized on a solid surface is one of the factors that affects the efficiency of solid-phase amplification (SP-PCR).
Jialing Huang   +9 more
doaj   +1 more source

Kinetic Study on the Thermal Denaturation of Rice Mitochondrial DNA

open access: yes, 1997
The thermal denaturation of the rice mitochondrial DNA in diFFerent solutions have been studied by using ultraviolet absorption spectrometry at 50 ℃, and their kinetic behaviour of the thermal denaturation has been discussed.The kinetic curves of the ...
周培疆   +5 more
core  

Thermal denaturation of dimeric and monomeric CLA.

open access: yes, 2014
Thermal denaturation profiles for CLA at pH 2 (□) and pH 7 (○) as monitored by the change in ellipticity values at 227 nm upon temperature increase.
Himadri Biswas (619013)   +1 more
core   +1 more source

Overcoming Transmission Barriers: A Dual‐Functional Adhesive Hydrogel for Direct Monkeypox Virus Neutralization and Wound Healing

open access: yesAdvanced Science, EarlyView.
MPXV infection leads to persistent viral replication and severe local inflammation, while existing treatments cannot simultaneously remove viruses and repair injured tissue. This study constructs Polymer@mPDA@Gel hydrogel via a two‐step hierarchical assembly method: mPDA anchors photothermal polymers to form antiviral photothermal subunits, which are ...
Ming Zhang   +7 more
wiley   +1 more source

Toward Personalized Theranostics: A Modular PET Platform for Antibody‐Based Imaging and Therapy

open access: yesAdvanced Science, EarlyView.
This modular, site‐specific antibody platform enables customizable conjugates for PET imaging and therapy. Interchangeable payloads – including radiometals, cytotoxics, and fluorophores – support adaptable, multimodal applications with limited off‐target effects. In vivo, the DFO/DOTAGA bischelate immunoconjugate provided clear tumor delineation in PET/
Delphine Vivier   +16 more
wiley   +1 more source

Utilization of thermal analysis in study on protein denaturation

open access: yes, 2017
This bachelor thesis deals with the use of techniques of thermal analysis in the study of thermal denaturation of proteins. As a model protein was chosen lysozyme. In the experimental part were used two methods of thermal analysis – differential scanning
Bošeľová, Miriam
core  

Effects of osmolytes on Pelodiscus sinensis creatine kinase: A study on thermal denaturation and aggregation

open access: yes, 2013
The protective effect of osmolytes on the thermal denaturation and aggregation of Pelodiscus sinensis muscle creatine kinase (PSCK) was investigated by a combination of spectroscopic methods and thermodynamic analysis.
Q X Jin   +7 more
core   +1 more source

METTL7A Downregulation Drives SLC1A5‐Mediated Glutamine Competition to Promote Tumor Proliferation and Suppress CD8+ T Cell Immunity in Gastric Cancer

open access: yesAdvanced Science, EarlyView.
GC cells enhance glutamine accumulation by upregulating SLC1A5 expression. This upregulation not only boosts GC cell proliferation, but also outcompetes CD8+ T cells for glutamine and suppresses their antitumor immunity. Mechanistically, METTL7A deficiency in GC induces SLC1A5 overexpression via an m6A‐dependent pathway and N‐glycosylation ...
Mingjun Sun   +16 more
wiley   +1 more source

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