Results 61 to 70 of about 116,561 (299)

Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound

FEBS Open Bio, EarlyView.
We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda, Natsue Maezono, Rina Uchikoshi, Nobuyuki Kato, Masanori Ikeda   +4 more
wiley   +1 more source

Thermal denaturation of bovine serum albumin and its oligomers and derivatives pH dependence. [PDF]

, 1995
In a previous paper, we report a preliminary DSC study on bovine (BSA) and human (HSA) serum albumins. However, at accurate HPLC analysis the commercial proteins show three peaks: Fraction V-I, probably globulins (as declared by the producers), Fraction ...
C. DE SENA, D. FESSAS, P. TRAMONTI, G. GRAZIANO, GIANCOLA, CONCETTA, P. Del Vecchio, S. CAPASSO, C. Giancola, G. BARONE, DEL VECCHIO, POMPEA GIUSEPPINA GRAZIA   +9 more
core   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

FEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh, Kamalika Mukherjee, Suvendra N. Bhattacharyya   +2 more
wiley   +1 more source

Reversible thermal denaturation of immobilized chymotrypsinogen [PDF]

, 1979
The reversible thermal denaturation of chymotrypsinogen A bound to the insoluble poly(2-hydroxyethyl methacrylate) Spheron matrix was investigated by the fluorescence method.
Eduard Brynda, Miroslav Bleha
core   +1 more source

Effect of defects on thermal denaturation of DNA oligomers [PDF]

Physical Review E, 2001
The effect of defects on the melting profile of short heterogeneous DNA chains are calculated using the Peyrard-Bishop Hamiltonian. The on-site potential on a defect site is represented by a potential which has only the short-range repulsion and the flat part without well of the Morse potential.
Singh, Navin, Singh, Yashwant
openaire   +3 more sources

Structural Guidance in 3D Microgel‐in‐Hydrogel Systems to Improve Chondrogenesis

Advanced Healthcare Materials, EarlyView.
The Anisogel, an anisotropic microgel‐in‐hydrogel system, guides chondrogenic differentiation of human mesenchymal stromal cells (hMSCs) modulated by the alignment and size of anisometric microgels. Chondrogenic markers are upregulated in an in vitro model and guided tissue infiltration is enhanced in a semi‐orthopedic mouse model due to the physico ...
Julia Kamp, Alisa C. Suturin, Claudia A. Garrido, Xiaole Tong, Jietao Xu, Nicole Kops, Lea‐Sophie Müller, Till Hülsmann, Abdolrahman Omidinia‐Anarkoli, Laura Klasen, Tamás Haraszti, Gerjo J. V. M. van Osch, Laura De Laporte   +12 more
wiley   +1 more source

Purification and Thermal denaturation of Truncated BfrB. [PDF]

, 2013
(A) Analysis of the purified truncated BfrB on a 12.5% SDS-polyacrylamide gel. M- Molecular weight markers, lanes 1–5 – purified protein. (B) Thermal denaturation curve of full length and truncated BfrB carried out by using circular dichroism. Black line
Vibha Gupta (44479), Garima Khare (212371), Prachi Nangpal (353421), Rakesh K. Gupta (255910), Anil K. Tyagi (21905), Nicholas K. Sauter (353422)   +5 more
core   +1 more source

Improved heat stability of goat milk through adjustment of salt balance

Applied Food Research
Heat treatment induces the denaturation of proteins in goat milk, increasing its susceptibility to age gelation and precipitation during shelf life.
Jinyu Xu, Yumeng Zhang, Yinping Guo, Xiaoyang Pang, Lu Liu, Jinghua Yu, Hongjuan Li, Jiaping Lv, Shuwen Zhang   +8 more
doaj   +1 more source

Thermal Denaturation of DNA Studied with Neutron Scattering [PDF]

Physical Review Letters, 2011
accepted for publication in Physical Review ...
Wildes, Andrew, Theodorakopoulos, Nikos, Valle Orero, Jessica, Cuesta-Lopez, Santiago, Garden, Jean-Luc, Peyrard, Michel   +5 more
openaire   +5 more sources

Lonicera japonica‐Derived Nanovesicles Ameliorate Acute Lung Injury by Suppressing Neutrophil Extracellular Traps Formation in Mice

Advanced Healthcare Materials, EarlyView.
(A) Isolation and purification of LDNVs. (B) Establishment of the ALI model and LDNVs delivery. (C) Therapeutic mechanisms of LDNVs in treating ALI. This scheme figure was drawn by Figdraw, ID: IUIIO21222. ABSTRACT Acute lung injury (ALI) is a lethal respiratory disease.
Xi Lin, Jian Lin, Yezi Zhang, Xinyan Zhang, Xinghua Liu, Hongying Cao, Huan Shen, Jianming Liang, Zhenhua Dai, Siyuan Xu, Xingdong Lin   +10 more
wiley   +1 more source