Results 51 to 60 of about 116,561 (299)
Journal of Lipid Research, 2012 Fusion of modified LDL in the arterial wall promotes atherogenesis. Earlier we showed that thermal denaturation mimics LDL remodeling and fusion, and revealed kinetic origin of LDL stability.
Mengxiao Lu +3 more
doaj +1 more source
Hydrogen exchange in thermally denatured ribonuclease [PDF]
Biochemistry, 1991 Hydrogen exchange has been used to test for the presence of nonrandom structure in thermally denatured ribonuclease A (RNase A). Quenched-flow methods and 2D 1H NMR spectroscopy were used to measure exchange rates for 36 backbone amide protons (NHs) at 65 degrees C and at pH* (uncorrected pH measured in D2O) values ranging from 1.5 to 3.8.
A D, Robertson, R L, Baldwin
openaire +2 more sources
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
Whole-body cryostimulation impact on blood serum thermal denaturation profiles of cross-country skiers [PDF]
, 2019 Blood plasma and serum are important diagnostic materials as they clearly reflect an individual’s metabolism. The study has evaluated the effect of whole-body cryostimulation (WBC) on the blood serum of professional cross-country skiers. The experiment
Michnik, Anna +4 more
core +1 more source
FEBS Open Bio, EarlyView.TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose +9 more
wiley +1 more source
Feasibility of microfluidic routes to monitor protein stability as a tool for bioprocessing [PDF]
, 2010 During the bioprocessing of therapeutics, proteins may become damaged leading to modifications and changes in stability. This may, as a consequence, cause serious and potentially fatal side effects when administered to patients making damage ...
Remtulla, N.
core
Thermal Denaturation Profiles [PDF]
, 2013 Thermal denaturation of M10.5 (A) compared with empty and peptide-filled H-2Kd (B) (modified from Figure 3A in Fahnestock et al. [21]). The CD signal at 223 nm was monitored as a function of temperature for insect cell-derived M10.5 and empty and peptide-
Rich Olson (275062) +3 more
core +1 more source
Meat and Muscle Biology, 2020 The objective of this study was to determine the thermodynamic and physical properties of beef strip loin steaks of varying thicknesses and USDA quality grades cooked with high and low grill surface temperatures.
Chris Kerth +7 more
doaj +2 more sources
Optimizing photoexcitation conditions for time‐resolved X‐ray solution scattering experiments
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering (TR‐XSS) is a powerful technique to visualize how proteins change their structure in real time after light activation. Selecting the right laser photoexcitation conditions—fluence, excitation geometry, and sample refresh rate—is critical to maximize the experimental signal while avoiding unwanted side effects ...
Matteo Levantino
wiley +1 more source
Thermal Denaturation of Fluctuating DNA Driven by Bending Entropy [PDF]
, 2007 International audienceA statistical model of homopolymer DNA, coupling internal base pair states (unbroken or broken) and external thermal chain fluctuations, is exactly solved using transfer kernel techniques.
Palmeri, John +2 more
core +1 more source