Results 71 to 80 of about 196,670 (297)

Improved heat stability of goat milk through adjustment of salt balance

Applied Food Research
Heat treatment induces the denaturation of proteins in goat milk, increasing its susceptibility to age gelation and precipitation during shelf life.
Jinyu Xu, Yumeng Zhang, Yinping Guo, Xiaoyang Pang, Lu Liu, Jinghua Yu, Hongjuan Li, Jiaping Lv, Shuwen Zhang   +8 more
doaj   +1 more source

Order of the phase transition in models of DNA thermal denaturation

, 2000
We examine the behavior of a model which describes the melting of double-stranded DNA chains. The model, with displacement-dependent stiffness constants and a Morse on-site potential, is analyzed numerically; depending on the stiffness parameter, it is ...
A. Campa, B. Simon, D. Cule, D. M. Kroll, D. Poland, D. Poland, J. A. Krumhansl, L. D. Landau, L. van Hove, M. Klaus, M. Klaus, M. M. Nieto, M. Peyrard, Michel Peyrard, Nikos Theodorakopoulos, R. A. Guyer, R. Blanckenberg, R. Blossey, R. Lipowsky, R. M. Wartell, S. W. Englander, T. Dauxois, T. Dauxois, Thierry Dauxois, V. Privman, Y-L Zhang   +25 more
core   +1 more source

Truncated and Helix-Constrained Peptides with High Affinity and Specificity for the cFos Coiled-Coil of AP-1 [PDF]

, 2013
Protein-based therapeutics feature large interacting surfaces. Protein folding endows structural stability to localised surface epitopes, imparting high affinity and target specificity upon interactions with binding partners.
A Patgiri, B Ibarra-Molero, BN Bullock, BR Brooks, BW Ozanne, CN Pace, D Aud, D Derossi, D Krylov, D Seebach, D Wang, D Wang, D Wang, D Wang, DA Guarracino, David P. Fairlie, DH Appella, DP Fairlie, DP Fairlie, E Vives, EF Wagner, EK O’Shea, EK O’Shea, EK O’Shea, F Bernal, F Bernal, GH Bird, GH Bird, Gloria Ruiz-Gómez, Huy N. Hoang, J Liu, JD Tyndall, JK Judice, JM Dixon, JM Mason, JM Mason, JM Mason, JM Mason, JN Glover, Jody M. Mason, Jose M. Sanchez-Ruiz, LD Walensky, LD Walensky, LK Henchey, LM Johnson, NE Shepherd, NE Shepherd, NE Shepherd, P Lavigne, PS Kutchukian, R Eferl, R Zenz, RE Moellering, RN Chapman, RO Crooks, RS Harrison, S Baek, SM Fuchs, T Wiseman, TA Libermann, Tara Rao, Timothy A. Hill, YW Kim, YW Kim   +63 more
core   +3 more sources

A Cryoprotectant‐Compatible Nanoporous Platform for Stable and Scalable Delivery of Biopharmaceuticals

Advanced Materials, EarlyView.
A cryoprotectant‐compatible nanoporous platform enables ambient‐stable and scalable delivery of gene editing therapeutics. By combining hierarchical pore architecture with optimized lyophilization chemistry, the system preserves Cas9‐RNP activity post‐freeze‐drying.
Sian Lee, Seongchan Kim, Jooyeun Chong, Min‐gyeong Kim, Kayeong Lim, Nan‐Ee Lee, Jahyun Koo, Jiheong Kang, Hyojin Lee   +8 more
wiley   +1 more source

Biophysical characterization of the outer membrane polysaccharide export protein and the polysaccharide co-polymerase protein from Xanthomonas campestris [PDF]

, 2014
This study investigated the structural and biophysical characteristics of GumB and GumC, two Xanthomonas campestris membrane proteins that are involved in xanthan biosynthesis. Xanthan is an exopolysaccharide that is thought to be a virulence factor that
Bianco, María Isabel, Ielmini, M. V., Ielpi, Luis, Jacobs, Melisa, Salinas, Silvina Rosa, Salvay, Andrés Gerardo   +5 more
core   +1 more source

Eutectozymes as Soft Hybrid Materials for Advanced Biocatalysis

Advanced Materials, EarlyView.
Eutectozymes are sustainable hybrid materials that embed a GOx–HRP cascade within hydrophobic eutectogels featuring a dual supramolecular–covalent network. This architecture preserves native enzyme structure and stability, enables efficient heterogeneous biocatalysis in aqueous media, and positions eutectogels as robust platforms for next‐generation ...
Manuel Eduardo Martinez Cartagena, Lucia Suarez, Aitor Ontoria, Francisca J. Benitez, Elixabete Rezabal, María Soledad Orellano, Marcelo Calderón, Cristián Huck‐Iriart, Agustin S. Picco, Matias L. Picchio, Ana Beloqui   +10 more
wiley   +1 more source

Electrochemical Study of Enzymatic Glucose Sensors Biocatalyst: Thermal Degradation after Long-Term Storage

Chemosensors, 2018
The thermal degradation related to stability in long-term storage of a carbon nanotube-based biosensor has been investigated. The effect of storage temperature on detachment and denaturation of glucose oxidase (GOx) biocatalyst has been proved.
Marcelinus Christwardana, Domenico Frattini   +1 more
doaj   +1 more source

Assembling a True “Olympic Gel” From over 16 000 Combinatorial DNA Rings

Advanced Materials, EarlyView.
Olympic gels are an elusive class of soft matter, consisting of molecular networks held together purely by mechanically interlocked rings. Their topological structure promises unique properties and functions, but their synthesis has proven notoriously difficult.
Sarah K. Speed, Yu‐Hsuan Peng, Azra Atabay, Krishna Gupta, Toni Müller, Carolin Fischer, Ilka M. Hermes, Jens‐Uwe Sommer, Michael Lang, Elisha Krieg   +9 more
wiley   +1 more source

Systematic FTIR Spectroscopy Study of the Secondary Structure Changes in Human Serum Albumin under Various Denaturation Conditions

Biomolecules, 2019
Human serum albumin (HSA) is the most abundant protein in blood plasma. HSA is involved in the transport of hormones, fatty acids, and some other compounds, maintenance of blood pH, osmotic pressure, and many other functions.
Dmitrii Usoltsev, Vera Sitnikova, Andrey Kajava, Mayya Uspenskaya   +3 more
doaj   +1 more source

Microfluidic DNA amplification - a review [PDF]

, 2009
The application of microfluidic devices for DNA amplification has recently been extensively studied. Here, we review the important development of microfluidic polymerase chain reaction (PCR) devices and discuss the underlying physical principles for the ...
Ozdemir, Pinar, Zhang, Yonghao
core   +1 more source