Results 1 to 10 of about 10,764 (259)

Articular chondrocytes from osteoarthritic knee joints of elderly, in vitro expanded in thermo-reversible gelation polymer (TGP), exhibiting higher UEA-1 expression in lectin microarray [PDF]

Regenerative Therapy, 2020
Autologous chondrocytes in vitro expanded, are used as tools of regenerative therapies for cartilage injuries. However, inability to maintain the hyaline phenotype both in vitro and post in vivo transplantation, remains one of the major hurdles for long ...
Shojiro Katoh, Atsuki Fujimaru, Rajappa Senthilkumar, Senthilkumar Preethy, Samuel JK. Abraham   +4 more
doaj   +4 more sources

Thermo-reversible gelation of self-assembled conducting polymer colloids [PDF]

Nature Communications
Electrically conductive hydrogels based on conducting polymers have found increased use in bioelectronics due to their low moduli that mimic biological tissues, their ability to transport both ionic and electronic charges, and their ease of processing in
Vidhika S. Damani, Xinran Xie, Rachel E. Daso, Khushboo Suman, Masoud Ghasemi, Weiran Xie, Ruiheng Wu, Yuhang Wu, Calvin L. Chao, Julian E. Alberto, Casey M. Lorch, Ai-Nin Yang, Dan My Nguyen, Tulaja Shrestha, Kayla Otero, Chun-Yuan Lo, Darrin J. Pochan, Enrique D. Gomez, Jonathan Rivnay, Laure V. Kayser   +19 more
doaj   +3 more sources

Application of a Thermo-Reversible Gelation Polymer, Mebiol Gel, for Stem Cell Culture and Regenerative Medicine [PDF]

Journal of Stem Cells and Regenerative Medicine, 2010
Recent studies have revealed the possible utility of a three-dimensional culture system using a thermo-reversible gelation polymer, Mebiol Gel. It is a purely synthesized biocompatible copolymer composed of thermoresponsive polymer blocks [poly(N ...
Nam-ho Huh, Ken Kataoka
doaj   +5 more sources

An Improved Encapsulation Method for Cryopreserving Hepatocytes for Functional Transplantation Using a Thermo-reversible Gelation Polymer. [PDF]

In Vivo, 2020
Thermo-reversible gelation polymer (TGP) can be converted into a gel state upon warming and liquid upon cooling. The present study aimed to demonstrate a new method for cryopreservation and encapsulation of rat hepatocytes using a TGP and their successful transplantation.The isolated rat hepatocytes were microencapsulated using TGP, and stored in ...
Yamada K, Aoki T, Enami Y, Tashiro Y, Zehaou Z, Koizumi T, Kusano T, Matsuda K, Wada Y, Shibata H, Tomioka K, Siriratsivawong K, Hoffman RM, Murakami M.   +13 more
europepmc   +4 more sources

A novel human donor cornea preservation cocktail incorporating a thermo-reversible gelation polymer (TGP), enhancing the corneal endothelial cell density maintenance and explant culture of corneal limbal cells. [PDF]

Biotechnol Lett, 2021
Abstract Purpose McCarey-Kaufman’s (MK) medium and Optisol-GS medium are the most commonly employed media for human donor corneal preservation. In this study, we evaluated the preservation efficacy of discarded human donor corneas using a Thermo-reversible gelation polymer (TGP) added to these two media.
Namitha B, Chitra MR, Bhavya M, Parikumar P, Katoh S, Yoshioka H, Iwasaki M, Senthilkumar R, Rajmohan M, Karthick R, Preethy S, Abraham SJK.   +11 more
europepmc   +4 more sources

Successful engraftment of epithelial cells derived from autologous rabbit buccal mucosal tissue, encapsulated in a polymer scaffold in a rabbit model of a urethral stricture, transplanted using the transurethral approach

Regenerative Therapy, 2021
Background: A pilot study reported an autologous buccal mucosal cell transplant in humans through the trans-urethral route using the buccal epithelium expanded and encapsulated in scaffold—hybrid approach to urethral stricture (BEES-HAUS), a minimally ...
Akio Horiguchi, Kenichiro Ojima, Masayuki Shinchi, Toshihiro Kushibiki, Yoshine Mayumi, Kosuke Miyai, Shojiro Katoh, Masayuki Takeda, Masaru Iwasaki, Vaddi Surya Prakash, Madasamy Balamurugan, Mathaiyan Rajmohan, Senthilkumar Preethy, Samuel JK. Abraham   +13 more
doaj   +1 more source

Lamotrigine-Loaded Poloxamer-Based Thermo-Responsive Sol–Gel: Formulation, In Vitro Assessment, Ex Vivo Permeation, and Toxicology Study

Gels, 2023
The present study aimed to prepare, characterize, and evaluate a thermo-responsive sol–gel for intranasal delivery of lamotrigine (LTG), which was designed for sustained drug delivery to treat epilepsy.
Maria Riaz, Muhammad Zaman, Huma Hameed, Hafiz Shoaib Sarwar, Mahtab Ahmad Khan, Ali Irfan, Gamal A. Shazly, Ana Cláudia Paiva-Santos, Yousef A. Bin Jardan   +8 more
doaj   +1 more source

UV-Crosslinked Poly(N-isopropylacrylamide) Interpenetrated into Chitosan Structure with Enhancement of Mechanical Properties Implemented as Anti-Fouling Materials

Gels, 2023
High-performance properties of interpenetration polymer network (IPN) hydrogels, based on physically crosslinked chitosan (CS) and chemically crosslinked poly(N-isopropylacrylamide) (PNiPAM), were successfully developed.
Isala Dueramae, Fumihiko Tanaka, Naoki Shinyashiki, Shin Yagihara, Rio Kita   +4 more
doaj   +1 more source

Self-healing metallo-supramolecular hydrogel based on specific Ni2+ coordination interactions of poly(ethylene glycol) with bistriazole pyridine ligands in the main chain [PDF]

, 2020
In this study, a supramolecular hydrogel formed by incorporating the 2,6-bis(1,2,3-triazol-4-yl)-pyridine (btp) ligand in the backbone of a polymer prepared by copper(I)-catalyzed alkyne-azide cycloaddition (CuAAC) "click" polyaddition reaction of 2,6 ...
Hoogenboom, Richard, Jerca, Valentin-Victor, Xu, Xiaowen   +2 more
core   +1 more source

Reversal of senescence-associated beta-galactosidase expression during in vitro three-dimensional tissue-engineering of human chondrocytes in a polymer scaffold

Scientific Reports, 2021
Regenerative medicine applications require cells that are not inflicted with senescence after in vitro culture for an optimal in vivo outcome. Methods to overcome replicative senescence include genomic modifications which have their own disadvantages. We
Shojiro Katoh, Atsuki Fujimaru, Masaru Iwasaki, Hiroshi Yoshioka, Rajappa Senthilkumar, Senthilkumar Preethy, Samuel J. K. Abraham   +6 more
doaj   +1 more source