Results 101 to 110 of about 68,485 (306)

Single cell analysis reveals immune cell-adipocyte crosstalk regulating the transcription of thermogenic adipocytes. [PDF]

, 2019
Immune cells are vital constituents of the adipose microenvironment that influence both local and systemic lipid metabolism. Mice lacking IL10 have enhanced thermogenesis, but the roles of specific cell types in the metabolic response to IL10 remain to ...
Ahn, In Sook, Arneson, Douglas, Diamante, Graciel, Feng, An-Chieh, Hart, Sydney K, Lee, Stephen D, Rajbhandari, Abha K, Rajbhandari, Prashant, Reue, Karen, Santos, Luis C, Smale, Stephen T, Thomas, Brandon J, Tontonoz, Peter, Vergnes, Laurent, Yang, Xia, Zaghari, Nima   +15 more
core   +1 more source

Torpor‐assisted migration: Regular use of shallow torpor reduces rest‐phase energy expenditure for songbirds during migration

Journal of Animal Ecology, EarlyView.
Migrating songbirds regularly use shallow torpor (up to 98% of birds for some species) to save energy (up to 42%) during inactive periods. This Ruby‐crowned Kinglet Corthylio calendula that was captured after a spring snowstorm highlights the value of being able to save energy when encountering unfavourable conditions.
Ryan A. C. Leys, Lily Hou, Liam P. McGuire   +2 more
wiley   +1 more source

Adipsin and adipocyte-derived C3aR1 regulate thermogenic fat in a sex-dependent fashion

JCI Insight
Thermogenesis in beige/brown adipose tissues can be leveraged to combat metabolic disorders such as type 2 diabetes and obesity. The complement system plays pleiotropic roles in metabolic homeostasis and organismal energy balance with canonical effects ...
Lunkun Ma, Ankit Gilani, Alfonso Rubio-Navarro, Eric Cortada, Ang Li, Shannon M. Reilly, Liling Tang, James C. Lo   +7 more
doaj   +1 more source

Fight Sitting with Movement [PDF]

, 2018
Today, Americans spend an average of 13 hours per day sitting. Sitting for as little as two continuous hours increases the risk of heart disease, diabetes, metabolic syndrome, cancer, back and neck pain, and other orthopedic problems.
Syed, Harris
core   +1 more source

Blubber Thickening Driven by UCP1 Inactivation: Insights from a Cetacean‐Like Transgenic Mouse Model

Integrative Zoology, EarlyView.
UCP1 inactivation of cetaceans in mice drives BAT whitening and iWAT hyperplasia, promoting fat accumulation for aquatic adaptation. Abstract Cetaceans possess thick blubber, a specialized adipose tissue essential for thermal insulation, a streamlined body form, energy storage, and buoyancy. However, the mechanisms that underpin this adaptation are not
Qian Zhang, Yuehua Wang, Hang Zhang, Guiping Xu, Shixia Xu, Guang Yang   +5 more
wiley   +1 more source

ELOVL3 regulates phospholipid homeostasis and thermogenesis in brown adipose tissue

Journal of Lipid Research
Nonshivering thermogenesis plays an important role in maintaining body temperature and energy homeostasis. Elongation of very long-chain fatty acid protein 3 (ELOVL3), which catalyzes the synthesis of C20-C24 fatty acids, is induced in brown adipose ...
Zhenbang Qin, Ping Wang, Ming Lu, Yue Tang, Qiuxiao Ren, Feng-Jung Chen, Weiping J. Zhang, Chunchun Wei   +7 more
doaj   +1 more source

Sympathetic nerve innervation is required for beigeing in white fat

Physiological Reports, 2019
It is increasingly recognized that activation of beige adipocyte thermogenesis by pharmacological or genetic approaches increases energy expenditure and alleviates obesity.
Qiang Cao, Jia Jing, Xin Cui, Hang Shi, Bingzhong Xue   +4 more
doaj   +1 more source

Genomic Investigations Unveil the Genetic Underpinnings of Environmental Adaptation in African Goat Populations

Integrative Zoology, EarlyView.
This study integrates genomics and landscape genetics to analyze African goat environmental adaptation. Analyzing 1591 samples, it finds population structure differentiates geographically into four groups, with gene flow between wild Yura goats and North Africans.
Weifeng Peng, Yihua Wang, Yiyuan Zhang, Lei Gao, Lili Wu, Shuping Wang, Yiyang Gao, Wanlu Shi, Kaixin Lu, Rong Deng, Junting Li, Jing Han, Xiaohui Lu, Yujie Liu, Xiaojiao Tang, Yunxia Zhang, Guoyin Li, Li Huang, Mingsheng Yang, Xiaoyan Li   +19 more
wiley   +1 more source

Identification of MEF2A, MEF2C, and MEF2D interactomes in basal and Fsk‐stimulated mouse MA‐10 Leydig cells

Andrology, EarlyView.
Abstract Background Myocyte enhancer factor 2 transcription factors regulate essential transcriptional programs in various cell types. The activity of myocyte enhancer factor 2 factors is modulated through interactions with cofactors, chromatin remodelers, and other regulatory proteins, which are dependent on cell context and physiological state.
Karine de Mattos, Marie‐Pier Scott‐Boyer, Arnaud Droit, Robert S. Viger, Jacques J. Tremblay   +4 more
wiley   +1 more source

Infrared thermography unveiled the variation of brown adipose tissue thermogenesis among East Asian adults

Physiological Reports
The thermogenesis of brown adipose tissue (BAT) is interesting because the contribution to human adaptation to cold and obesity resistance has been suggested.
Yuka Ishida, Kazuhiro Nakayama
doaj   +1 more source