Results 111 to 120 of about 85,969 (275)

Is thermogenesis really needed for brown adipose tissue–mediated metabolic benefit?

The Journal of Clinical Investigation, 2022
Brown adipose tissue (BAT) dissipates energy in the form of heat and functions as a metabolic sink for lipids, glucose, and branched-chain amino acids. Enhanced BAT thermogenesis is thought to tightly couple with beneficial energy metabolism. However, in
Jin-Seon Yook, Shingo Kajimura
doaj   +1 more source

Adipsin and adipocyte-derived C3aR1 regulate thermogenic fat in a sex-dependent fashion

JCI Insight
Thermogenesis in beige/brown adipose tissues can be leveraged to combat metabolic disorders such as type 2 diabetes and obesity. The complement system plays pleiotropic roles in metabolic homeostasis and organismal energy balance with canonical effects ...
Lunkun Ma, Ankit Gilani, Alfonso Rubio-Navarro, Eric Cortada, Ang Li, Shannon M. Reilly, Liling Tang, James C. Lo   +7 more
doaj   +1 more source

Macrophage glutaminolysis supports thermogenesis to control cardiometabolic traits [PDF]

, 2022
C. Borowczyk, J. Merlin, S. Ivanov, L. Yvan-Charvet   +3 more
openalex   +1 more source

AMP-Activated Protein Kinase (AMPK) Regulates Energy Metabolism through Modulating Thermogenesis in Adipose Tissue

Frontiers in Physiology, 2018
Obesity occurs when excess energy accumulates in white adipose tissue (WAT), whereas brown adipose tissue (BAT), which is specialized in dissipating energy through thermogenesis, potently counteracts obesity.
Lingyan Wu, Li-na Zhang, Bo-Han Li, Haowen Jiang, Yanan Duan, Zhifu Xie, Lin Shuai, Jia Li, Jingya Li   +8 more
semanticscholar   +1 more source

The Role of the Sympathetic Nervous System in the Hypothermic Effect of d-Fenfluramine [PDF]

, 2002
Experiments in this dissertation were conducted to characterize the effects of d-fenfluramine on body temperature and the mechanisms by which d-fenfluramine alter body temperature.
Subramanian, Srividya
core   +1 more source

Alcohol and the regulation of energy balance: overnight effects on diet-induced thermogenesis and fuel storage [PDF]

, 1996
Peter R. Murgatroyd, M. L. H. M. Van De Ven, G R Goldberg, Andrew M. Prentice   +3 more
openalex   +1 more source

Fighting obesity by targeting factors regulating beige adipocytes. [PDF]

, 2018
Purpose of reviewThe current review provides an update on secreted factors and mechanisms that promote a thermogenic program in beige adipocytes, and their potential roles as therapeutic targets to fight obesity.Recent findingsWe outline recent studies ...
Koliwad, Suneil K, McQueen, Allison E, Wang, Jen-Chywan   +2 more
core   +1 more source

Group IIA secreted phospholipase A2 (PLA2G2A) augments adipose tissue thermogenesis [PDF]

, 2021
Michael Kuefner, Erin J. Stephenson, Mladen Savikj, Heather S. Smallwood, Qingming Dong, Christine Payré, Gérard Lambeau, Edwards A. Park   +7 more
openalex   +1 more source

Infrared thermography unveiled the variation of brown adipose tissue thermogenesis among East Asian adults

Physiological Reports
The thermogenesis of brown adipose tissue (BAT) is interesting because the contribution to human adaptation to cold and obesity resistance has been suggested.
Yuka Ishida, Kazuhiro Nakayama
doaj   +1 more source

Acyl CoA-binding protein in brown adipose tissue acts as a negative regulator of adaptive thermogenesis

Molecular Metabolism
Objective: Defective activity of brown adipose tissue (BAT) is linked to obesity and cardiometabolic diseases. While much is known regarding the biological signals that trigger BAT thermogenesis, relatively little is known about the repressors that may ...
Albert Blasco-Roset, Tania Quesada-López, Alberto Mestres-Arenas, Joan Villarroya, Francisco J. Godoy-Nieto, Rubén Cereijo, Celia Rupérez, Ditte Neess, Nils J. Færgeman, Marta Giralt, Anna Planavila, Francesc Villarroya   +11 more
doaj   +1 more source