Results 121 to 130 of about 65,191 (322)

Treatment of Early‐Onset Specified and Unspecified Bipolar Disorders: A Systematic Review and Strategies for Identifying and Managing a Thermally Dysregulated Subtype in Children

open access: yesActa Psychiatrica Scandinavica, EarlyView.
ABSTRACT Introduction Bipolar disorder (BD), characterized by extreme mood shifts between mania and depression, can manifest in childhood, and pose treatment challenges. Treatment for full‐criteria BD I or II in children has been partially described in the literature, but major uncertainties exist regarding non‐classic presentations, which were ...
Demitri F. Papolos   +2 more
wiley   +1 more source

Creatine and low-dose lithium supplementation separately alter energy expenditure, body mass, and adipose metabolism for the promotion of thermogenesis

open access: yesiScience
Summary: Nutraceutical approaches to promote adipose tissue thermogenesis may help to prevent obesity onset. Creatine is a critical regulator of adipose metabolic function and low-dose lithium supplementation has been shown to promote adipose ...
M.S. Finch   +13 more
doaj  

Identification of MEF2A, MEF2C, and MEF2D interactomes in basal and Fsk‐stimulated mouse MA‐10 Leydig cells

open access: yesAndrology, EarlyView.
Abstract Background Myocyte enhancer factor 2 transcription factors regulate essential transcriptional programs in various cell types. The activity of myocyte enhancer factor 2 factors is modulated through interactions with cofactors, chromatin remodelers, and other regulatory proteins, which are dependent on cell context and physiological state.
Karine de Mattos   +4 more
wiley   +1 more source

Innovative pharmacotherapy for hepatic metabolic and chronic inflammatory diseases in China

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Liver disease constitutes a significant global health concern, particularly in China where it has distinctive characteristics. China grapples with a staggering 300 million cases, predominantly due to hepatitis B and metabolic non‐alcoholic fatty liver disease. Additionally, hepatocellular carcinoma has become a prevalent which is a lethal type
Feng Zhang   +5 more
wiley   +1 more source

The association of motivational factors with weight loss and treatment time in a publicly funded weight management clinic

open access: yesClinical Obesity, EarlyView.
Summary The objective of the study is to explore differences in weight loss (WL) and treatment time with having health, mobility, and/or aesthetics motivations for attempting WL. Data from 7540 adults with overweight or obesity who participated in a publicly funded weight management programme at the Wharton Medical Clinic were analysed.
Amir Yazdanparast   +4 more
wiley   +1 more source

Synergistical Induction of Apoptosis via Cold Atmospheric Plasma and Nanohydroxyapatite for Selective Inhibition of Oral Squamous Cell Carcinoma in Tumour Microenvironment

open access: yesCell Proliferation, EarlyView.
The synergistic effects of microwave‐induced CAP and pH‐responsive NH2‐nHA on OSCC cells were investigated, unveiling novel molecular mechanisms. The study highlights CAP+NH2‐nHA's dual action, inducing diverse apoptotic pathways and establishing a ROS‐Ca2+ amplifying loop, promising in cancer therapy.
Wenting Qi   +6 more
wiley   +1 more source

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