Results 71 to 80 of about 45,421 (286)
Recent genetic evidence has linked WNT downstream mutations to fat distribution. However, the roles of WNTs in human obesity remain unclear. Here, the authors screen all Wnt‐related paracrine factors in 1994 obese cases and 2161 controls using whole ...
Yingkai Sun +19 more
doaj +1 more source
The Liver as a Hub in Thermogenesis [PDF]
Manipulating thermogenesis could increase energy expenditure and improve metabolism. Brown fat is a major site of nonshivering thermogenesis, but other tissues, notably muscle and liver, can contribute to cold adaptation. In this issue, Simcox et al.
openaire +2 more sources
Circadian rhythm disruption impairs metabolic regulation, appetite control, and vascular function, promoting obesity and cardiovascular diseases. Evidence highlights a bidirectional relationship where metabolic disorders further disturb circadian timing.
Ghizal Fatima +4 more
wiley +1 more source
The development of strategies that promote the activation of adaptive thermogenesis in brown and beige adipose tissues is expected to lead to advances in the prevention and treatment of obesity, diabetes, and cardiovascular diseases.
Bruna Bombassaro +7 more
doaj +1 more source
Cold exposure induces lipid dynamics and thermogenesis in brown adipose tissue of goats
Background Adaptive thermogenesis by brown adipose tissue (BAT) is important to the maintenance of temperature in newborn mammals. Cold exposure activates gene expression and lipid metabolism to provide energy for BAT thermogenesis. However, knowledge of
Xin Liu +10 more
doaj +1 more source
Multiomics Approaches Identify Biomarkers for BAT Thermogenesis
Brown adipose tissue (BAT) thermogenesis confers beneficial effects on metabolic diseases such as obesity and type-2 diabetes. Nevertheless, the mechanism and lipid driving the process that evokes this response have not been investigated yet.
Zijing Wang (3090645) +17 more
core +1 more source
Overpotential-derived thermogenesis in mitochondrial respiratory chain
Thermogenesis, which is associated with intracellular aerobic respiration, is a fundamental function that controls the internal temperatures of living organisms. Proton leakage is considered to be correlated with thermogenesis through aerobic respiration.
Kotaro, Takeyasu +3 more
core +1 more source
Intuitively, an animal that is able to produce more heat internally (e.g. through BAT-thermogenesis) could tolerate having a greater exposed surface area.
Roderich Groß (791841) +3 more
core +1 more source
A brown fat-enriched adipokine Adissp controls adipose thermogenesis and glucose homeostasis
The signaling mechanisms regulating adipose thermogenesis have not been fully elucidated. Here, the authors show that a brown fat-enriched adipokine ADISSP promotes adipose thermogenesis and improves metabolic health independently of b-adrenergic ...
Qingbo Chen +9 more
doaj +1 more source
Water-Induced Thermogenesis [PDF]
Drinking lots of water is commonly espoused in weight loss regimens and is regarded as healthy; however, few systematic studies address this notion. In 14 healthy, normal-weight subjects (seven men and seven women), we assessed the effect of drinking 500 ml of water on energy expenditure and substrate oxidation rates by using whole-room indirect ...
Michael, Boschmann +8 more
openaire +2 more sources

