Results 211 to 220 of about 83,845 (311)

Editorial: Targeting adipose tissue for the treatment of metabolic alterations. [PDF]

Front Pharmacol
Flori L, Ramos-Molina B, Calderone V, Martelli A.   +3 more
europepmc   +1 more source

Bergmann's rule: Why does body size increase with latitude?

Functional Ecology, Volume 40, Issue 4, Page 830-843, April 2026.
Read the free Plain Language Summary for this article on the Journal blog. Abstract Bergmann's rule describes the tendency for endothermic body size to increase with latitude, a pattern often attributed to climatic factors. However, the underlying developmental and evolutionary mechanisms remain debated.
Kurt M. Ongman, Carl G. Lundblad, Courtney J. Conway   +2 more
wiley   +1 more source

Myeloid GHSR Deficiency Protects Against Thermogenic Impairment in Aging Through Immune Remodeling of Brown Adipose Tissue. [PDF]

Cells
Han HW, Kim DM, Baratiboldaji R, Wang H, Liu Z, Shen Z, Jha DK, Teferra T, Septiningsih EM, Patil B, Sun Y.   +10 more
europepmc   +1 more source

Effect of high fat feeding on metabolic efficiency and mitochondrial oxidative activity in adult rats. [PDF]

, 2003
BARLETTA, ANTONIO, Botta M., CRESCENZO, RAFFAELLA, IOSSA, SUSANNA, Lionetti L., LIVERINI, GIOVANNA, MOLLICA, MARIA PINA   +6 more
core   +2 more sources

Pck1 Deficiency Drives Mitochondrial Dysfunction and Cellular Senescence in Adipocytes

Aging Cell, Volume 25, Issue 4, April 2026.
Phosphoenolpyruvate carboxykinase 1 (Pck1) expression is downregulated in aging white adipose tissue. Adipocyte Pck1 deficiency impairs TCA cycle cataplerosis, causing fumarate accumulation. Excess fumarate disrupts mitochondrial homeostasis, triggers oxidative stress and mtDNA release, activating cGAS–STING signaling and driving inflammaging ...
Yiting Lei, Meng Yang, Xiaoyun Jiang, Yujie Zhang, Yuzhi Chen, Weiheng Xie, Qihui Dai, Weihong Qin, Xiuqin Deng, Xiaojun Zhang, Zhongjun Zhou, Gonghua Huang, Xinguang Liu   +12 more
wiley   +1 more source

The Physiological Significance of TRP and Piezo Channels as Physical Stimulus Sensors in Brown Adipocytes. [PDF]

Cells
Uchida K, Iwase M.
europepmc   +1 more source

The Preservation of Muscle Mitochondrial Machinery During Hypometabolic Hibernation in Scandinavian Brown Bears (Ursus arctos)

Acta Physiologica, Volume 242, Issue 4, April 2026.
ABSTRACT Aim Unlike humans, brown bears (Ursus arctos) uniquely preserve skeletal muscle mass and function during months of hibernation despite prolonged fasting and inactivity. We investigated how mitochondrial energetics respond in skeletal muscle to support this remarkable resilience.
Audrey Bergouignan, John Noone, Charlotte Brun, Laura Cussonneau, Alexandre Geffroy, Cecile Coudy‐Gandilhon, Isabelle Chery, Alina Lynn Evans, Jon Martin Arnemo, Jonas Kindberg, Guillemette Gauquelin‐Koch, Donal O'Gorman, Etienne Lefai, Fabrice Bertile   +13 more
wiley   +1 more source

Diet-Induced Browning of White Adipose Tissue: Molecular Targets, Mechanisms, and Therapeutic Potential. [PDF]

Curr Issues Mol Biol
Yang ZD, Chen JW, Mei YX, Xia XW, Gong YJ, Ding WJ.   +5 more
europepmc   +1 more source

Deciphering the Presence of Active Interscapular Brown Adipose Tissue in Humans

Acta Physiologica, Volume 242, Issue 4, April 2026.
ABSTRACT Brown adipose tissue (BAT) is increasingly recognized as a metabolically active tissue in humans, although its physiological relevance remains incompletely understood. In rodents, BAT is well characterized, with interscapular BAT (iBAT) representing the main thermogenic depot.
Joaquin Sanchez‐Gomez, Samuel Ruiz‐Campos, Anabel Chica‐Perez, Andrés Baena‐Raya, Francisco M. Acosta, Christian Wolfrum, Patrick C. N. Rensen, Tania Romacho, Borja Martinez‐Tellez   +8 more
wiley   +1 more source

Thermogenesis is limited by cellular competence. [PDF]

Front Cell Dev Biol
Brown AC.
europepmc   +1 more source