Results 31 to 40 of about 83,845 (311)

Brown adipose TRX2 deficiency activates mtDNA-NLRP3 to impair thermogenesis and protect against diet-induced insulin resistance

open access: yesJournal of Clinical Investigation, 2022
Brown adipose tissue (BAT), a crucial heat-generating organ, regulates whole-body energy metabolism by mediating thermogenesis. BAT inflammation is implicated in the pathogenesis of mitochondrial dysfunction and impaired thermogenesis.
Yanrui Huang   +8 more
semanticscholar   +1 more source

Lipokines and Thermogenesis [PDF]

open access: yesEndocrinology, 2019
Abstract Adaptive thermogenesis is a catabolic process that consumes energy-storing molecules and expends that energy as heat in response to environmental changes. This process occurs primarily in brown and beige adipose tissue. Thermogenesis is regulated by many factors, including lipid derived paracrine and endocrine hormones called ...
Matthew D Lynes   +2 more
openaire   +2 more sources

PERAN LEMAK COKLAT DALAM MEKANISME PRODUKSI PANAS

open access: yesJurnal Berita Ilmu Keperawatan, 2008
Thermoregulation system have two process heat production, they are shivering and non shivering thermogenesis. Non shivering thermogenesis more happens in newborn human especially to adapt of low temperatures.
Siti Arifah, Kartinah Kartinah
doaj   +1 more source

mTORC1 inhibition uncouples lipolysis and thermogenesis in white adipose tissue to contribute to alcoholic liver disease

open access: yesHepatology Communications, 2023
Background:. Adipose tissue thermogenic activities use fatty acids from lipolysis for heat generation. Therefore, a tight coupling between lipolysis and thermogenesis is physiologically imperative in maintaining not only body temperature but also lipids ...
Qing Song   +11 more
doaj   +1 more source

mTORC2 sustains thermogenesis via Akt-induced glucose uptake and glycolysis in brown adipose tissue [PDF]

open access: yes, 2016
Activation of non-shivering thermogenesis (NST) in brown adipose tissue (BAT) has been proposed as an anti-obesity treatment. Moreover, cold-induced glucose uptake could normalize blood glucose levels in insulin-resistant patients.
Albert V   +12 more
core   +4 more sources

Thermogenesis by THADA [PDF]

open access: yesDevelopmental Cell, 2017
THADA has been associated with cold adaptation and diabetes in humans, but the cellular and molecular basis of its function has been unknown. Moraru and colleagues (2017) report in this issue of Developmental Cell that it triggers thermogenesis by uncoupling ATP hydrolysis from calcium transport into the endoplasmic reticulum.
Chatterjee, Nirmalya, Perrimon, Norbert
openaire   +3 more sources

Aqueous extracts of Aconite promote thermogenesis in rats with hypothermia via regulating gut microbiota and bile acid metabolism

open access: yesChinese Medicine, 2021
Background Intermittent or prolonged exposure to severe cold stress disturbs energy homeostasis and can lead to hypothermia, heart failure, Alzheimer’s disease, and so on. As the typical “hot” traditional Chinese medicine, Aconite has been widely used to
Juan Liu   +4 more
doaj   +1 more source

Perilipin regulates the thermogenic actions of norepinephrine in brown adipose tissue [PDF]

open access: yes, 2007
In response to cold, norepinephrine (NE)-induced triacylglycerol hydrolysis (lipolysis) in adipocytes of brown adipose tissue (BAT) provides fatty acid substrates to mitochondria for heat generation (adaptive thermogenesis).
Bianco, Antonio C.   +12 more
core   +1 more source

UCP1 Dependent and Independent Thermogenesis in Brown and Beige Adipocytes

open access: yesFrontiers in Endocrinology, 2020
Mammals have two types of thermogenic adipocytes: brown adipocytes and beige adipocytes. Thermogenic adipocytes express high levels of uncoupling protein 1 (UCP1) to dissipates energy in the form of heat by uncoupling the mitochondrial proton gradient ...
K. Ikeda, Tetsuya Yamada
semanticscholar   +1 more source

Water-Induced Thermogenesis [PDF]

open access: yesThe Journal of Clinical Endocrinology & Metabolism, 2003
Drinking lots of water is commonly espoused in weight loss regimens and is regarded as healthy; however, few systematic studies address this notion. In 14 healthy, normal-weight subjects (seven men and seven women), we assessed the effect of drinking 500 ml of water on energy expenditure and substrate oxidation rates by using whole-room indirect ...
Michael, Boschmann   +8 more
openaire   +2 more sources

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