Results 31 to 40 of about 33,124 (202)
Physiological Research, 2006 Apart from thyroid hormones, as the main hormonal regulators of obligatory thermogenesis, and catecholamines, as major hormonal regulators of facultative thermogenesis, production of heat in homeotherms can also be influenced by steroids. Generally, hormones can influence heat production by regulating the activity of various enzymes of oxidative ...
R, Hampl, L, Stárka, L, Janský
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Proteostasis in thermogenesis and obesity
Biological Chemistry, 2020 AbstractThe proper production, degradation, folding and activity of proteins, proteostasis, is essential for any cellular function. From single cell organisms to humans, selective pressures have led to the evolution of adaptive programs that ensure proteins are properly produced and disposed of when necessary. Environmental factors such as temperature,
Bartelt, A., Widenmaier, S.B.
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Molecular Metabolism, 2020 Objective: Brown adipose tissue (BAT)–mediated thermogenesis plays a key role in energy homeostasis and the maintenance of body temperature. Previous work suggests that brain-derived neurotrophic factor (BDNF) is involved in BAT thermogenesis, but the ...
He You, Pengcheng Chu, Wei Guo, Bai Lu
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Energy expenditure during overfeeding
Nutrition & Metabolism, 2006 The large inter-individual variation in weight gain during standardized overfeeding together with a weight gain that is often less than theoretically calculated from the energy excess suggest that there are differences between persons in the capacity to ...
Westerterp Klaas R, Joosen Annemiek MCP
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Scientific Reports, 2023 Obesity and type 2 diabetes are two closely related diseases representing a serious threat worldwide. An increase in metabolic rate through enhancement of non-shivering thermogenesis in adipose tissue may represent a potential therapeutic strategy ...
Jordi Rodó +9 more
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Latest advances in the regulatory genes of adipocyte thermogenesis
Frontiers in Endocrinology, 2023 An energy imbalance cause obesity: more energy intake or less energy expenditure, or both. Obesity could be the origin of many metabolic disorders, such as type 2 diabetes and cardiovascular disease.
Tao Nie +3 more
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Cold exposure induces lipid dynamics and thermogenesis in brown adipose tissue of goats
BMC Genomics, 2022 Background Adaptive thermogenesis by brown adipose tissue (BAT) is important to the maintenance of temperature in newborn mammals. Cold exposure activates gene expression and lipid metabolism to provide energy for BAT thermogenesis. However, knowledge of
Xin Liu +10 more
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Molecular Metabolism, 2022 Objective: Genome-wide association studies identified ORMDL3 as an obesity-related gene, and its expression was negatively correlated with body mass index.
Yu Song +11 more
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A brown fat-enriched adipokine Adissp controls adipose thermogenesis and glucose homeostasis
Nature Communications, 2022 The signaling mechanisms regulating adipose thermogenesis have not been fully elucidated. Here, the authors show that a brown fat-enriched adipokine ADISSP promotes adipose thermogenesis and improves metabolic health independently of b-adrenergic ...
Qingbo Chen +9 more
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Frontiers in Physiology, 2018 Thermoregulation is necessary to maintain energy homeostasis. The novel discovery of brown adipose tissue (BAT) in humans has increased research interests in better understanding BAT thermogenesis to restore energy balance in metabolic disorders.
Carla Frare +6 more
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