Results 31 to 40 of about 62,258 (326)

Evolutionary history of the UCP gene family: gene duplication and selection [PDF]

BMC Evol. Biol. 8 (2008) 306, 2008
BACKGROUND: The uncoupling protein (UCP) genes belong to the superfamily of electron transport carriers of the mitochondrial inner membrane. Members of the uncoupling protein family are involved in thermogenesis and determining the functional evolution of UCP genes is important to understand the evolution of thermo-regulation in vertebrates.
arxiv   +1 more source

Autonomic regulation of brown adipose tissue thermogenesis in health & disease: Potential clinical applications for altering BAT thermogenesis

Frontiers in Neuroscience, 2014
From mouse to man, brown adipose tissue (BAT) is a significant source of thermogenesis contributing to the maintenance of the body temperature homeostasis during the challenge of low environmental temperature.
Domenico eTupone, Christopher J. Madden, Shaun F. Morrison   +2 more
doaj   +1 more source

QPLOT Neurons—Converging on a Thermoregulatory Preoptic Neuronal Population

Frontiers in Neuroscience, 2021
The preoptic area of the hypothalamus is a homeostatic control center. The heterogeneous neurons in this nucleus function to regulate the sleep/wake cycle, reproduction, thirst and hydration, as well as thermogenesis and other metabolic responses ...
Brian A. Upton, Brian A. Upton, Brian A. Upton, Brian A. Upton, Shane P. D’Souza, Shane P. D’Souza, Shane P. D’Souza, Richard A. Lang, Richard A. Lang, Richard A. Lang, Richard A. Lang   +10 more
doaj   +1 more source

Simulation toolkits at the molecular scale for trans-scale thermal signaling [PDF]

arXiv, 2023
Thermogenesis is a physiological activity of releasing heat that originates from intracellular biochemical reactions. Recent experimental studies discovered that externally applied heat changes intracellular signaling locally, resulting in global changes in cell morphology and signaling.
arxiv  

RNA-binding protein YBX3 promotes PPARγ-SLC3A2 mediated BCAA metabolism fueling brown adipogenesis and thermogenesis. [PDF]

Mol Metab
Objective: Activating brown adipose tissue (BAT) thermogenesis is a promising approach to combat obesity and metabolic disorders. The post-transcriptional regulation of BAT thermogenesis mediated by RNA-binding proteins (RBPs) is still not fully ...
Chen LY, Wang LW, Wen J, Cao JD, Zhou R, Yang JL, Xiao Y, Su T, Huang Y, Guo Q, Zhou HY, Luo XH, Feng X.   +12 more
europepmc   +2 more sources

Nardilysin in adipocytes regulates UCP1 expression and body temperature homeostasis

Scientific Reports, 2022
Brown adipose tissue (BAT) dissipates chemical energy as heat through uncoupling protein 1 (UCP1). The induction of mitochondrial reactive oxygen species (ROS) in BAT was recently identified as a mechanism that supports UCP1-dependent thermogenesis.
Sayaka Saijo, Mikiko Ohno, Hirotaka Iwasaki, Shintaro Matsuda, Kiyoto Nishi, Yoshinori Hiraoka, Natsuki Ide, Takeshi Kimura, Eiichiro Nishi   +8 more
doaj   +1 more source

A Synergistic Antiobesity Effect by a Combination of Capsinoids and Cold Temperature Through Promoting Beige Adipocyte Biogenesis. [PDF]

, 2016
Beige adipocytes emerge postnatally within the white adipose tissue in response to certain environmental cues, such as chronic cold exposure. Because of its highly recruitable nature and relevance to adult humans, beige adipocytes have gained much ...
Bannai, Makoto, Kajimura, Shingo, Nogusa, Yoshihito, Ohyama, Kana, Shinoda, Kosaku, Suzuki, Katsuya   +5 more
core   +2 more sources

Thermal stress induces glycolytic beige fat formation via a myogenic state. [PDF]

, 2019
Environmental cues profoundly affect cellular plasticity in multicellular organisms. For instance, exercise promotes a glycolytic-to-oxidative fibre-type switch in skeletal muscle, and cold acclimation induces beige adipocyte biogenesis in adipose tissue.
A Jaworski, AA Lans van der, Andrew Brack, Annarita Scaramozza, C Trapnell, Carlos Henrique Sponton, DC Berry, ES Bachman, H Ohno, J Nedergaard, J Sanchez-Gurmaches, J Wu, JR Arch, JZ Long, K Ikeda, K Nishijo, K Shinoda, Kazuki Tajima, Kenji Ikeda, Kosaku Shinoda, Kyeongkyu Kim, L Kazak, L Vishvanath, L Ye, LZ Sharp, M Razzoli, ME Lidell, MJ Hanssen, ML Gantner, MS Rodeheffer, P Cohen, P Seale, Qiang Wang, S Collins, S Heinz, S Jung, S Kajimura, S Tripathi, Shingo Kajimura, T Buch, T Yoneshiro, Takeshi Yoneshiro, VK Mootha, Y Hasegawa, YH Lee, YH Tseng, Yong Chen, Zachary Brown, ZF Yang   +48 more
core   +2 more sources

Diet-induced adaptive thermogenesis requires neuropeptide FF receptor-2 signalling

Nature Communications, 2018
Excess caloric intake leads to increased thermogenesis in brown adipose tissue, to limit weight gain. Here, the authors show that neuropeptide FF receptor-2 signalling promotes thermogenesis via control of NPY expression in the arcuate nucleus, and that ...
Lei Zhang, Chi Kin Ip, I-Chieh J. Lee, Yue Qi, Felicia Reed, Tim Karl, Jac Kee Low, Ronaldo F. Enriquez, Nicola J. Lee, Paul A. Baldock, Herbert Herzog   +10 more
doaj   +1 more source

Response of appetite and potential appetite regulators following intake of high energy nutritional supplements [PDF]

, 2015
Background: The net clinical benefit of high-energy nutritional supplements (HENSDs) consumption is lower than expected. Objectives: To investigate the extent to which consumption of oral HENSD in the fasted state reduces energy intake in slim females
Arvanitidou, Eirini-Iro, Fatima, Sadia, Gerasimidis, Konstantinos, Malkova, Dalia, Tsiountsioura, Melina, Wright, Charlotte   +5 more
core   +1 more source