Results 91 to 100 of about 1,873 (179)

Molecular mechanisms of thermosensation

Folia Pharmacologica Japonica, 2004
We feel a wide range of temperatures spanning from cold to heat. Within this range, temperatures over about 43 degrees C and below about 15 degrees C evoke not only a thermal sensation, but also a feeling of pain. In mammals, six thermosensitive ion channels have been reported, all of which belong to the TRP (transient receptor potential) super family.
openaire   +3 more sources

RETINOBLASTOMA‐RELATED Has Both Canonical and Noncanonical Regulatory Functions During Thermo‐Morphogenic Responses in Arabidopsis Seedlings

Plant, Cell &Environment, Volume 48, Issue 2, Page 1217-1231, February 2025.
ABSTRACT Warm temperatures accelerate plant growth, but the underlying molecular mechanism is not fully understood. Here, we show that increasing the temperature from 22°C to 28°C rapidly activates proliferation in the apical shoot and root meristems of wild‐type Arabidopsis seedlings.
Rasik Shiekh Bin Hamid, Fruzsina Nagy, Nikolett Kaszler, Ildikó Domonkos, Magdolna Gombos, Annamária Marton, Csaba Vizler, Eszter Molnár, Aladár Pettkó‐Szandtner, László Bögre, Attila Fehér, Zoltán Magyar   +11 more
wiley   +1 more source

Heat application in live cell imaging

FEBS Open Bio, Volume 14, Issue 12, Page 1940-1954, December 2024.
Thermal modulation in live‐cell imaging with a high spatiotemporal resolution allows the investigation of biomolecular reactions like protein deactivation and unfolding, and cellular processes like calcium signaling. Local changes in temperature are induced via infrared (IR) irradiation of water (direct), magnetic or radiative excitation of absorber ...
Linda Sistemich, Simon Ebbinghaus
wiley   +1 more source

TRP Channels Entering the Structural Era [PDF]

, 2013
Transient receptor potential (TRP) channels are important in many neuronal and non-neuronal physiological processes. The past 2 years have seen much progress in the use of structural biology techniques to elucidate molecular mechanisms of TRP channel ...
Gaudet, Rachelle
core   +1 more source

Unlocking the therapeutic potential of TRPV3: Insights into thermosensation, channel modulation, and skin homeostasis involving TRPV3

BioEssays, Volume 46, Issue 7, July 2024.
TRPV3, a warmth sensor, plays a role in maintaining skin homeostasis. The discovery of membrane protein TMEM79 modulation on TRPV3 in keratinocytes underscores their role in warmth sensation. Thus, comprehensive understanding of TRPV3 in physiology and pathology yields insight into skin function.
Jing Lei, Makoto Tominaga
wiley   +1 more source

Measurement and Control of Single Nitrogen-Vacancy Center Spins above 600 K

, 2012
We study the spin and orbital dynamics of single nitrogen-vacancy (NV) centers in diamond between room temperature and 700 K. We find that the ability to optically address and coherently control single spins above room temperature is limited by ...
Alkauskas, A., Awschalom, D. D., Buckley, B. B., Christle, D. J., Toyli, D. M., Van de Walle, C. G.   +5 more
core   +2 more sources

Allosteric Activation of Bacterial Response Regulators: the Role of the Cognate Histidine Kinase Beyond Phosphorylation [PDF]

, 2014
Response regulators are proteins that undergo transient phosphorylation, connecting specific signals to adaptive responses. Remarkably, the molecular mechanism of response regulator activation remains elusive, largely because of the scarcity of ...
Aguilar, Pablo Sebastián, Albanesi, Daniela, Botti, Horacio, Buschiazzo, Alejandro, Cybulski, Larisa Estefania, de Mendoza, Diego, Larrieux, Nicole, Mechaly, Ariel, Nieves, Marcos, Ruetalo, Natalia, Trajtenberg, Felipe   +10 more
core   +4 more sources

TRP ion channels in thermosensation, thermoregulation and metabolism [PDF]

Temperature, 2015
In humans, the TRP superfamily of cation channels includes 27 related molecules that respond to a remarkable variety of chemical and physical stimuli. While physiological roles for many TRP channels remain unknown, over the past years several have been shown to function as molecular sensors in organisms ranging from yeast to humans.
Hong Wang, Jan Siemens
openaire   +2 more sources

Heat Resistant Organic Dyes for High Temperature Luminescent Temperature Sensing

Advanced Sensor Research, Volume 3, Issue 4, April 2024.
A blue organic emitter is developed with high heat resistance, due to an offset between thermally populating to high‐lying emissive states and facilitated nonradiative decay. By hybridizing with a yellow ESIPT fluorophore, a sensitive ratiometric high‐temperature film thermometer is demonstrated, which enables large‐area thermal mapping and multiple ...
Xuesen Qian, Mengfei Kong, Linyi Song, Guochang Yue, Yong Zhang, Yan Qian, Quli Fan   +6 more
wiley   +1 more source

'Add, stir and reduce': Yersinia spp. as model bacteria for pathogen evolution [PDF]

, 2016
In the study of molecular microbiology and bacterial genetics, pathogenic species of the Yersinia genus have been pillars for research aimed at understanding how bacteria evolve into mammalian pathogens.
McNally, A, Reuter, S, Thomson, NR, Wren, BW   +3 more
core   +4 more sources