Results 191 to 200 of about 38,411 (253)

Nanostructured Deep Eutectic Systems in Healthcare: From Bioactive Solvents to Intelligent Biointerfaces, Wearables, and AI‐Driven Design

Advanced NanoBiomed Research, Volume 6, Issue 10, October 2026.
Beyond the green solvent paradigm, this review redefines Deep Eutectic Systems (DES) as programmable supramolecular nanoassemblies. We survey their biomedical convergence: stabilizing thermolabile mRNA to enable cold chain‐free logistics, reshaping transdermal microneedle delivery, enabling long‐term wearables via eutectogels, and utilizing Generative ...
Jeesu Moon, Min Seo Kim, Jae‐Seung Lee
wiley   +1 more source

Different mechanisms for human rhinovirus survival in the presence of deleterious amino acid substitutions at virion protein-protein or RNA-protein interfaces. [PDF]

J Virol
Gil-Redondo JC, Riomoros-Barahona V, Valiente L, Valbuena A, Mateu MG.   +4 more
europepmc   +1 more source

Immunoinformatics‐Based Design of a Multi‐Epitope Vaccine Targeting a Conserved Copper–Associated Protein in Neisseria gonorrhoeae

Biotechnology and Applied Biochemistry, Volume 73, Issue 5, Page 2373-2387, October 2026.
ABSTRACT Neisseria gonorrhoeae poses an urgent public health challenge due to rapidly increasing antimicrobial resistance and the absence of an effective vaccine. Targeting conserved bacterial pathways involved in essential physiological processes may provide new opportunities for vaccine antigen discovery.
Sinethemba H. Yakobi, Uchechukwu U. Nwodo   +1 more
wiley   +1 more source

From smoke to symbiosis: dissecting KAI2 signalling in rice using the specific receptor agonist, dMGer. [PDF]

Plant Physiol
Bradley JM.
europepmc   +1 more source

Targeting Amastigote and Trypomastigote Phases: Multi‐Epitope Vaccine Strategy Against Trypanosoma cruzi

Biotechnology and Applied Biochemistry, Volume 73, Issue 5, Page 2457-2481, October 2026.
ABSTRACT Effective vaccines against Trypanosoma cruzi, the causative agent of Chagas disease, are urgently needed. Here, we report the design and in silico validation of a novel multiepitope vaccine construct targeting the key surface proteins ASP‐2 and gp82. Using a comprehensive immunoinformatics pipeline, we identified and selected 38 potent T‐cell (
Maria Karolaynne da Silva, Caio Patrício de Souza Sena, Davi Serradella Vieira, Magdi E. A. Zaki, Leow Chiuan Yee, Shahina Akter, Umberto Laino Fulco, Jonas Ivan Nobre Oliveira, João Firmino Rodrigues‐Neto   +8 more
wiley   +1 more source

Biochemical and structural characterization of AmyY from <i>Alkalimonas</i> sp. NCh-2 reveals a class of metal-free α-amylases in glycoside hydrolase family 13. [PDF]

Appl Environ Microbiol
Zhao F, Xu T-T, Yu C-M, Ding J-M, Zhou B-H, Zhang Y-Z, Chen X-L, Zhang Y, Zhang Y-Q, Sun M-L.   +9 more
europepmc   +1 more source

Spray‐Dried Engineered Escherichia coli Whole‐Cell Biocatalysts Enable Cell Recycling and In Vivo α‐Ketoglutarate and NADPH Regeneration for Efficient Codeine Manufacture

Biotechnology and Bioengineering, Volume 123, Issue 10, Page 2629-2642, October 2026.
ABSTRACT A recombinant whole‐cell biocatalytic approach provides several advantages over isolated enzymes, such as improved enzyme stability, in vivo cofactor regeneration, and the facilitation of cascade reactions within a single cell. Whole‐cell biocatalysis has gained attention in medicinal opioid production, due to its technical and economic ...
Ali Jahanian, Carlos Horacio Luna‐Flores, Xu Li, Sally L. Gras, Robert E. Speight   +4 more
wiley   +1 more source

Computational Design of a Thermo-Acidostable Endo-Polygalacturonase for Efficient Juice Extraction. [PDF]

Foods
Cheng Z, Hou G, Zhang T, Feng D, Zhang Y, Wang X, Yang L, Luo M, Pan L.   +8 more
europepmc   +1 more source

Structural Characterization and In Vitro α‐Amylase Inhibitory and Bile Acid‐Binding Properties of a Glucan Isolated From Fermented Cowpea Natto

Food Science &Nutrition, Volume 14, Issue 10, October 2026.
Cowpea (Vigna unguiculata L.) seeds were fermented with Bacillus subtilis natto, freeze‐dried, milled, and subjected to hot‐water extraction, protein removal, alcohol precipitation, and lyophilization to obtain the crude glucan fraction (JD‐F). JD‐F was further purified by DEAE‐Sepharose Fast Flow anion‐exchange chromatography and size‐exclusion ...
Jinyi Yu, Mengyue Xu, Hui Li, Enzhao Yan, Huifang Niu, Qin Liu, Hongxing Zhang, Hongbo Wang   +7 more
wiley   +1 more source

Rigidifying Flexible Regions of a Bacterial Laccase Enables High-Temperature Aflatoxin B1 Degradation. [PDF]

Microorganisms
Xiong D, Sun H, Sun Y, Li P, Long M.
europepmc   +1 more source