Results 61 to 70 of about 104,002 (235)
Rubredoxin Variant Folds without Iron [PDF]
, 1999 Pyroccocus furiosus rubredoxin (PFRD), like most studied hyperthermophilic proteins, does not undergo reversible folding. The irreversibility of folding is thought to involve PFRD’s iron-binding site.
Mayo, Stephen L., Strop, Pavel
core +1 more source
Engineering of a Thermostable Biocatalyst for the Synthesis of 2‐O‐Glucosylglycerol [PDF]
, 2021 Jorick Franceus +3 more
openalex +1 more source
Journal of Biological Chemistry, 2019 Rational design–guided improvement of protein thermostability typically requires identification of residues or regions contributing to instability and introduction of mutations into these residues or regions. One popular method, B-FIT, utilizes B-factors
Heng Tang +5 more
semanticscholar +1 more source
Advanced ScienceUnderstanding the mechanism underlying thermostabilization in naturally stable enzymes and enhancing the thermostability of unstable enzymes are crucial aspects in enzyme engineering.
Min Liao +9 more
doaj +1 more source
SCHEMA Recombination of a Fungal Cellulase Uncovers a Single Mutation That Contributes Markedly to Stability [PDF]
, 2009 A quantitative linear model accurately (R^2 = 0.88) describes the thermostabilities of 54 characterized members of a family of fungal cellobiohydrolase class II (CBH II) cellulase chimeras made by SCHEMA recombination of three fungal enzymes ...
Alan Villalobos +23 more
core +2 more sources
Two strategies to engineer flexible loops for improved enzyme thermostability
Scientific Reports, 2017 Flexible sites are potential targets for engineering the stability of enzymes. Nevertheless, the success rate of the rigidifying flexible sites (RFS) strategy is still low due to a limited understanding of how to determine the best mutation candidates ...
Haoran Yu +3 more
semanticscholar +1 more source
Thermostability as a highly dependent prion strain feature
Scientific Reports, 2019 Prion diseases are caused by the conversion of physiological PrPC into the pathogenic misfolded protein PrPSc, conferring new properties to PrPSc that vary upon prion strains.
A. Marín-Moreno +5 more
semanticscholar +1 more source
Optimizing enzyme thermostability by combining multiple mutations using protein language model
mLifeOptimizing enzyme thermostability is essential for advancements in protein science and industrial applications. Currently, (semi‐)rational design and random mutagenesis methods can accurately identify single‐point mutations that enhance enzyme ...
Jiahao Bian +4 more
doaj +1 more source
Gas Atmosphere Formed in Casting by Full Mold Process
Archives of Metallurgy and Materials, 2014 A test mold was designed to investigate the full mold process. Pressure changes in a gap developing between the pattern made of foamed polystyrene and the raising column of liquid alloy were determined. Studies were conducted pouring molds with cast iron
Mocek J., Chojecki A.
doaj +1 more source
Bacteria and bacterial envelope components enhance mammalian reovirus thermostability
PLoS Pathogens, 2017 Enteric viruses encounter diverse environments as they migrate through the gastrointestinal tract to infect their hosts. The interaction of eukaryotic viruses with members of the host microbiota can greatly impact various aspects of virus biology ...
Angela K. Berger +3 more
semanticscholar +1 more source