Results 41 to 50 of about 55,424 (301)
Identification of novel neutralizing determinants for protection against HCV
Hepatology, EarlyView., 2022 Identification of novel neutralizing determinants for protection against hepatitis C virus. Abstract Background and Aims HCV evasion of neutralizing antibodies (nAb) results in viral persistence and poses challenges to the development of an urgently needed vaccine.
Garazi P. Alzua +12 more
wiley +1 more source
BMC Biotechnology, 2018 Background Phytase supplied in feeds for monogastric animals is important for improving nutrient uptake and reducing phosphorous pollution. High-thermostability phytases are particularly desirable due to their ability to withstand transient high ...
Nanyu Han +7 more
doaj +1 more source
THERMOSTABILITY OF PDC: FACTORS AFFECTING THERMOSTABILITY AND WAYS TO IMPROVE IT
European Science, 2023 Polycrystalline diamond, with its high hardness and wear resistance as well as other excellent properties such as low friction, high thermal conductivity, high corrosion resistance and low electrical conductivity, plays a leading role in the selection ...
Oleksandr Sokolov, Vladyslav Harhin
openaire +1 more source
Oxyalkylated alcohols phthalates [PDF]
Нанотехнологии в строительстве, 2019 Polyvinyl chloride (PVC) is used to obtain a wide range of materials for various purposes. High demand of PVC is explained by possibility to modify polyvinyl chloride and produce broad range of materials with improved properties as well as to have cost
Albina R. Maskova +4 more
doaj +1 more source
Frontiers in Bioengineering and Biotechnology, 2021 The protein–protein interaction assay is a key technology in various fields, being applicable in drug screening as well as in diagnosis and inspection, wherein the stability of assays is important.
Yuki Ohmuro-Matsuyama +6 more
doaj +1 more source
The Nicastrin ectodomain adopts a highly thermostable structure [PDF]
, 2011 Nicastrin is a type I transmembrane glycoprotein, which is part of the high molecular weight gamma-secretase complex. gamma-Secretase is one of the key players associated with the generation of Alzheimer's disease pathology, since it liberates the ...
Beyer, Klaus +6 more
core +2 more sources
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Frontiers in Bioengineering and Biotechnology, 2022 In order to improve enzymatic properties of glucoamylases, six recombinant genes GA1–GA6 were created by domain shuffling of glucoamylase genes GAA1 from Aspergillus niger Ld418AI and GATE from Talaromyces emersonii Ld418 TE using overlap extension PCR ...
Zhongxiu Chen +15 more
doaj +1 more source
Glycosylation of hyperthermostable designer cellulosome components yields enhanced stability and cellulose hydrolysis [PDF]
, 2020 Biomass deconstruction remains integral for enabling second‐generation biofuel production at scale. However, several steps necessary to achieve significant solubilization of biomass, notably harsh pretreatment conditions, impose economic barriers to ...
Bayer, Edward A. +8 more
core
Nitrene Transfer Catalyzed by a Non-Heme Iron Enzyme and Enhanced by Non-Native Small-Molecule Cofactors [PDF]
, 2019 Transition-metal catalysis is a powerful tool for the construction of chemical bonds. Here we show that a non-heme iron enzyme can catalyze olefin aziridination and nitrene C–H insertion, and that these activities can be improved by directed evolution ...
Arnold, Frances H. +3 more
core +1 more source