Results 41 to 50 of about 40,909 (278)
Cryo-electron microscopy reveals two distinct type IV pili assembled by the same bacterium
Type IV pili are flexible filaments on the surface of bacteria, consisting of a helical assembly of pilin proteins. Here, Neuhaus et al. show that the bacterium Thermus thermophilus produces two forms of type IV pilus, differing in structure, protein ...
Alexander Neuhaus+9 more
doaj +1 more source
Structure and conformational plasticity of the intact Thermus thermophilus V/A-type ATPase
Innovations in an ATPase/ATP synthase Enzymes that couple the chemical energy of adenosine triphosphate (ATP) to movement of ions across a membrane are present in all domains of life.
Long Zhou, L. Sazanov
semanticscholar +1 more source
Profiling Thermus thermophilus Argonaute Guide DNA Sequence Preferences by Functional Screening. [PDF]
Prokaryotic Argonautes (pAgo) are an increasingly well-studied class of guided endonucleases, and the underlying mechanisms by which pAgo generate nucleic acid guides in vivo remains an important topic of investigation.
Hunt EA+4 more
europepmc +2 more sources
Background Thermus thermophilus and Deinococcus radiodurans belong to a distinct bacterial clade but have remarkably different phenotypes. T. thermophilus is a thermophile, which is relatively sensitive to ionizing radiation and desiccation, whereas D ...
Daly Michael J+8 more
doaj +1 more source
Improving the Fidelity of Thermus Thermophilus DNA Ligase [PDF]
The DNA ligase from Thermus thermophilus (Tth DNA ligase) seals single-strand breaks (nicks) in DNA duplex substrates. The specificity and thermostability of this enzyme are exploited in the ligase chain reaction (LCR) and ligase detection reaction (LDR) to distinguish single base mutations associated with genetic diseases.
Francis Barany+2 more
openaire +3 more sources
A Hyperthermoactive-Cas9 Editing Tool Reveals the Role of a Unique Arsenite Methyltransferase in the Arsenic Resistance System of Thermus thermophilus HB27. [PDF]
Arsenic detoxification systems can be found in a wide range of organisms, from bacteria to humans. In a previous study, we discovered an arsenic-responsive transcriptional regulator in the thermophilic bacterium Thermus thermophilus HB27 (TtSmtB).
Gallo G+9 more
europepmc +2 more sources
Multicopper oxidases (MCOs) catalyze the oxidation of a variety of substrates while reducing oxygen into water through four copper atoms. As an additional feature, some MCOs display an enhanced activity in solution in the presence of Cu2+.
V. Hitaishi+8 more
semanticscholar +1 more source
Transcription factors are proteins that recognize specific DNA sequences and affect local transcriptional processes. They are the primary means by which all organisms control specific gene expression.
James Shell Cox, Michael W. Van Dyke
doaj +1 more source
Unconventional lateral gene transfer in extreme thermophilic bacteria. [PDF]
Conjugation and natural competence are two major mechanisms that explain the acquisition of foreign genes throughout bacterial evolution. In recent decades, several studies in model organisms have revealed in great detail the steps involved in such ...
Berenguer, José+4 more
core +1 more source
A DNA sequencing-based strategy was applied to study the microbiology of Continental-type cheeses with a pink discoloration defect. The basis for this phenomenon has remained elusive, despite decades of research.
Lisa Quigley+12 more
doaj +1 more source