Results 71 to 80 of about 40,909 (278)

A two-domain elevator mechanism for sodium/proton antiport [PDF]

, 2013
Sodium/proton (Na+/H+) antiporters, located at the plasma membrane in every cell, are vital for cell homeostasis1. In humans, their dysfunction has been linked to diseases, such as hypertension, heart failure and epilepsy, and they are well-established ...
A MacKerell, A Rimon, A Wiedenmann, A Wiedenmann, ACE Dahl, AJ McCoy, Alexander D. Cameron, B Hess, B Hess, C Hunte, Chiara Lee, Christoph von Ballmoos, CL Brett, D Drew, D Drew, D Taglicht, D Taglicht, David Drew, David L. Dotson, DE Drew, DJ Slotboom, E Padan, E Padan, E Pinner, E Screpanti, EF Pettersen, EM Furrer, FW Studier, G Bricogne, G Bussi, G Winter, GJ Kleywegt, H Li, Hae Joo Kang, IC West, IT Arkin, JAD Mackerell Jr, JB Klauda, K Cowtan, KA Scott, KA Williams, KA Williams, KR Vinothkumar, L Kozachkov, L Potterton, M Appel, M Maes, M Parrinello, M Schushan, N Kuwabara, N Michaud-Agrawal, N Reyes, NJ Hu, Oliver Beckstein, P Emsley, P Goswami, PD Adams, PJ Bond, PJ Stansfeld, Povilas Uzdavinys, RR Ishmukhametov, S Miyamoto, S Wagner, SD Knight, Simon Newstead, So Iwata, T Hisamitsu, T Kawate, T Mager, T Noumi, TA Jones, TD Goddard, U Essmann, W Humphrey, W Kabsch, WL Jorgensen, Y Sonoda   +76 more
core   +2 more sources

Mammalian Tolerance to Amino Acid Heterochirality

ChemBioChem, Accepted Article.
Organisms use amino acids predominantly in l‐configuration. On the other hand, a series of studies show that a variety of d‐amino acids also occur in mammals and amino acid homochirality is not complete. Mammals de novo synthesize most amino acids with l‐configuration, but serine and aspartate are converted from l‐ to d‐configuration by endogenous ...
Jumpei Sasabe, Sakiko Taniguchi, Kenichiro Adachi, Xuan Tran, Masataka Suzuki   +4 more
wiley   +1 more source

Low-Molecular-Weight Thiols and Thioredoxins Are Important Players in Hg(II) Resistance in Thermus thermophilus HB27

Applied and Environmental Microbiology, 2017
Mercury (Hg), one of the most toxic and widely distributed heavy metals, has a high affinity for thiol groups. Thiol groups reduce and sequester Hg. Therefore, low-molecular-weight (LMW) and protein thiols may be important cell components used in Hg ...
J. Norambuena, Y. Wang, Thomas E Hanson, J. Boyd, T. Barkay   +4 more
semanticscholar   +1 more source

Programming Green Light‐Responsive Hydrogels: From Photo‐Weakening to Photo‐Unresponsiveness and Photo‐Strengthening

Chemistry – A European Journal, Volume 31, Issue 16, March 17, 2025.
The light response of CarHc protein‐based hydrogels can be alterted from photo‐weakening, to photo‐strengthening, or becoming light‐unresponsive depending on the added cofactors AdoCbl and Co2+. Under green light, CarHc tetramers disassembly weakens the hydrogel, while excess AdoCbl crosslinking poly‐histidine tags strengthens it.
Saskia Frank, Seraphine V. Wegner
wiley   +1 more source

Enhancing Allosteric Inhibition in Thermus thermophilus Phosphofructokinase [PDF]

Biochemistry, 2015
The coupling between the binding of the substrate Fru-6-P and the inhibitor phospho(enol)pyruvate (PEP) in phosphofructokinase (PFK) from the extreme thermophile Thermus thermophilus is much weaker than that seen in a PFK from Bacillus stearothermophilus.
Gregory D. Reinhart, Maria S. McGresham
openaire   +3 more sources

Trehalose biosynthesis in Thermus thermophilus RQ-1: biochemical properties of the trehalose-6-phosphate synthase and trehalose-6-phosphate phosphatase [PDF]

, 2005
The genes for trehalose synthesis in Thermus thermophilus RQ-1, namely otsA [trehalose-phosphate synthase (TPS)], otsB [trehalose-phosphate phosphatase (TPP)], and treS [trehalose synthase (maltose converting) (TreS)] genes are structurally linked.
Alarico, Susana, Costa, Milton S. da, Silva, Zélia   +2 more
core   +1 more source

PGLN: A newly identified amino phosphoglycolipid species in Thermus thermophilus HB8

Biochemistry and Biophysics Reports, 2022
Thermus thermophilus has several minor lipid molecules with structures that have not been described yet. In this study, we identified a new lipid molecule in T.
Naoki Nemoto, Masahiko Kawaguchi, Kei Yura, Haruo Shimada, Yoshitaka Bessho   +4 more
doaj  

Recombinant Photolyase-Thymine Alleviated UVB-Induced Photodamage in Mice by Repairing CPD Photoproducts and Ameliorating Oxidative Stress

Antioxidants, 2022
Cyclobutane pyrimidine dimers (CPDs) are the main mutagenic DNA photoproducts caused by ultraviolet B (UVB) radiation and represent the major cause of photoaging and skin carcinogenesis.
Zhaoyang Wang, Ziyi Li, Yaling Lei, Yuan Liu, Yuqing Feng, Derong Chen, Siying Ma, Ziyan Xiao, Meirong Hu, Jingxian Deng, Yuxin Wang, Qihao Zhang, Yadong Huang, Yan Yang   +13 more
doaj   +1 more source

Identification of CO‐binding modes in the CuB site of bovine cytochrome c oxidase by spatial mapping of binding energy

The FEBS Journal, EarlyView.
Quantum simulations of the catalytic center (CuB) of cytochrome c oxidase, driving the electron transport system, revealed a crucial role of Val243 in modulation of ligand binding. Val243‐driven interaction facilitates hybridization between CO and Fe orbitals, thus highlighting Val243's impact on electronic structure and ligand dynamics.
Jiyoung Kang, Toru Matsuoka, Masaru Tateno   +2 more
wiley   +1 more source

An extracellular polyhydroxybutyrate depolymerase in Thermus thermophilus HB8

Applied Microbiology and Biotechnology, 2009
The thermophilic bacterium Thermus thermophilus HB8 has been characterized as a polyhydroxybutyrate (PHB)-degrading microorganism since it grows efficiently and forms clear zones on agar plates containing PHB as sole carbon source. T. thermophilus extracellular PHB depolymerase was purified to homogeneity using an affinity chromatography protocol.
Papaneophytou, C., Pantazaki, A.A., Kyriakidis, D.A.   +2 more
openaire   +4 more sources