Results 111 to 120 of about 11,765 (225)

Thiadiazoles. III*. Some 5-Substituted Derivatives of 2-Amino-1,3,4-Thiadiazoles and Some Mesoionic 1,3,4-Thiadiazoles

Croatica Chemica Acta, 1971
New derivatives of 1,3,4-thiadiazoles with potential phytohormonic (compds. I-V) and antibacterial (compds. VI-IX) activity have been prepared. Mesoionic structure of the compounds VI- IX is indicated by their IR and UV spectra.
Kuftinec, J., Kolbah, D.
openaire   +2 more sources

Functionalization of 2-Mercapto-5-methyl-1,3,4-thiadiazole: 2-(ω-Haloalkylthio) Thiadiazoles vs. Symmetrical Bis-Thiadiazoles

Molecules
A study on the functionalisation of 2-mercapto-5-methyl-1,3,4-thiadiazole has been conducted, yielding two series of products: 2-(ω-haloalkylthio)thiadiazoles and symmetrical bis-thiadiazoles, with variable chain lengths. The experimental conditions were optimised for each class of compounds by altering the base used and the reagents’ proportions ...
Zhanina S. Petkova, Rusi I. Rusew, Boris L. Shivachev, Vanya B. Kurteva   +3 more
openaire   +3 more sources

A REVIEW ON THE VARIOUS BIOLOGICAL ACTIVITIES OF THIADIAZOLE [PDF]

, 2015
Thiadiazole and their derivatives have been studied colossally because of their wide range of biological activity. They are found to be effectual as antibacterial, antimalarial, antiviral, antiinflammatory, anticancer and antianthelminthic agents ...
Neetu, Taya, Poonam, Mehta, Dinesh
core  

Novel 5‑Sulfonyl-1,3,4-thiadiazole-Substituted Flavonoids as Potential Bactericides and Fungicides: Design, Synthesis, Three-Dimensional Quantitative Structure–Activity Relationship Studies

Flavonoids, ubiquitous natural products, provide sources for drug discovery owing to their structural diversity, broad-spectrum pharmacological activity, and excellent environmental compatibility. To develop antibacterial and antifungal agents with novel
Qingqing Wang (141110), Weihua Zhang (44940), Yufei Li (433737), Peng Dai (1327728), Jian Jiao (364961), Yuchuan Zhu (8127462), Peng Teng (158324)   +6 more
core   +1 more source

Synthesis and Antifungal Activities of Perillyl Alcohol Based 1,3,4-Thiadiazole-Thioether Compounds. [PDF]

Chem Biodivers
Xiong Y, Zhang Y, Cui Y, Hu M, Zhuo M, Duan W, Mo Q.   +6 more
europepmc   +1 more source

Aggregation-Modulated Excited-State Intramolecular Proton Transfer and Antifungal Potential of Selected 1,3,4-Thiadiazole Derivatives. [PDF]

Int J Mol Sci
Budziak-Wieczorek I, Rząd K, Koselski M, Górecki A, Kachel-Górecka M, Matwijczuk A, Gładyszewska B, Burg P, Okoń S, Matwijczuk A.   +9 more
europepmc   +1 more source

Structural design and cytotoxic profiling of a novel 1,3,4-thiadiazole derivative targeting MCF-7 and HCT-116 cell lines: synthesis, cytotoxicity, and <i>in silico</i> study. [PDF]

RSC Adv
Sayed M, Mohammed E, Aboubaker DH, El-Rashedy AA, Hassanien R, Tolba MS, Ahmed M.   +6 more
europepmc   +1 more source

Identification of a Novel 1,3,4-Thiadiazole-Based Scaffold as a Plasmepsin V Inhibitor. [PDF]

ACS Omega
Zelencova-Gopejenko D, Bolsakova J, Rudusa L, Kitoka K, Jekabsons A, Skvorcova M, Jirgensons A, Bobrovs R.   +7 more
europepmc   +1 more source

Synthesis, Characterization, Molecular Docking Study and Biological Evaluation of Novel 1,3,4-Thiadiazole-Based Heterocycles as Potential Anticancer and Antioxidant Agents. [PDF]

Chem Biol Drug Des
El-Metwaly NM, Alrefaei AF, Alshareef HF, Almehmadi SJ, Alotaibi FA, Alshammari NM, Ebaid MS, Katouah HA.   +7 more
europepmc   +1 more source

Synthesis of Mesoionic 1,3,4-Thiadiazole-2-Thiolates

A reliable synthesis of C5-unsubstituted 1,3,4-thiadiazole-2-thiolates is described that avoids potentially explosive or laborious steps. This work presents a reliable method for preparing the starting material dithioformate from carbon disulfide and ...
Andreas Schmidt, Sean Ray Kahnert
core   +1 more source