Results 91 to 100 of about 10,659 (219)
Novel 5‑Sulfonyl-1,3,4-thiadiazole-Substituted Flavonoids as Potential Bactericides and Fungicides: Design, Synthesis, Three-Dimensional Quantitative Structure–Activity Relationship Studies [PDF]
Flavonoids, ubiquitous natural products, provide sources for drug discovery owing to their structural diversity, broad-spectrum pharmacological activity, and excellent environmental compatibility. To develop antibacterial and antifungal agents with novel
Qingqing Wang (141110) +6 more
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A second polymorph of 3,4-bis(6-bromopyridin-3-yl)-1,2,5-thiadiazole
IUCrData, 2016 The title compound, C12H6Br2N4S, a second polymorph in the triclinic space group P-1, is presented. As in the earlier reported monoclinic polymorph in the space group C2/c [Becker et al. (2016). Chem. Eur. J. In the press], the thiadiazole ring is planar
Lisanne Becker +4 more
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Synthesis and Anti-Trypanosoma cruzi Activity of New Pyrazole-Thiadiazole Scaffolds
MoleculesChagas disease, a silent but widespread disease that mainly affects a socioeconomically vulnerable population, lacks innovative safe drug therapy. The available drugs, benznidazole and nifurtimox, are more than fifty years old, have limited efficacy, and
Thamyris Perez de Souza +6 more
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THE SYNTHESIS OF NEW 1,2,3-THIADIAZOLE DERIVATIVES [PDF]
, 1970 The reactions of 1,2,3-thiadiazole-4-carbonyl chloride with the appropriate amines led to formation of the following amides in good yield: N-ethyl-1,2,3-thiadia- zole-4-carboxamide; N-methyl-1,2,3-thiadiazole-4-carbox- amide; N-cyclohexyl-1,2,3 ...
PATTERSON, RONALD BRINTON
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Acta Chimica Slovenica, 2015 The acidity constants Ka1 and Ka2 of 2-(5-mercapto-1,3,4-thiadiazol-2-ylthio)acetic acid have been determined both by experimental and theoretical methods.
Raluca Oana Pop +6 more
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Química NovaIn this study, new 1,3,4-thiadiazole compounds were synthesised and characterised by FT-IR, 1H-NMR, UV-vis spectroscopy and elemental analysis, Furthermore, the relationship between the electronic and spectral data of the 16 conformers of each compound ...
Muhammet Serdar Çavuş, Tuğba Çelik
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Síntese de novos mesógenos derivados do heterocíclo imidazo[2,1-b][1,3,4]tiadiazol [PDF]
, 2009 TCC (graduação) - Universidade Federal de Santa Catarina, Centro de Ciências Físicas e Matemáticas, Curso de Química.A síntese de seis novas moléculas derivadas do heterociclo imidazo[2,1-b][1,3,4]tiadiazol foram realizadas a partir da construções de ...
Ferraz Neto, José
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2,5-Bis[(3-chlorobenzyl)sulfanyl]-1,3,4-thiadiazole [PDF]
, 2012 The complete molecule of the title compound, C16H12Cl2N2S3, is generated by crystallographic twofold symmetry, with the S atom of the thiadiazole ring lying on the rotation axis.
Na-Bo Sun, Wei Ke, Jian-Zhong Jin
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Synthesis and in vitro Evaluation of New Benzothiazole Derivatives as Schistosomicidal Agents
Molecules, 2007 A series of benzothiazol-2-yl-dithiocarbamates 3a-d along with their copper complexes 4a-c were synthesized via the reaction of suitable alkyl, aralkyl or heteroaryl halides with the sodium salt of benzothiazol-2-yl-dithiocarbamic acid, followed by ...
Mona A Mahran +3 more
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Thiadiazole‐induced myelodysplasia in rats [PDF]
Teratology, 1974 AbstractPregnant Wistar rats were injected ip with a teratogenic dose (100 mg/kg) of 2‐amino‐l,3,4‐thiadiazole hydro‐chloride (ATDA) on day 11 of gestation (sperm day = day 0). Pregnancy was terminated at various intervals following drug injection.
openaire +2 more sources