Results 71 to 80 of about 11,765 (225)
Smart Molecules, EarlyView.A smart design strategy for NIR‐II organic fluorophores is proposed by combining self‐driven Iterative evolution, deep Learning, and fragment‐based assembly. This work establishes a broadly applicable approach for molecular design, accelerating the discovery of NIR‐II fluorophores and extending to optoelectronic materials and therapeutic compounds ...
Yu Zhang +6 more
wiley +1 more source
Antifungal Activity of Novel Indole Derivatives Containing 1,3,4-Thiadiazole
In this study, 24 indole derivatives containing 1,3,4-thiadiazole were discovered and synthesized. The target compounds’ antifungal efficacy against 14 plant pathogenic fungal pathogens was then determined in vitro.
Bangcan He (18452570) +8 more
core +1 more source
, 2015 International audienceAbstract An original and efficient palladium‐catalyzed amination of imidazo[2,1‐ b ][1,3,4]thiadiazole is reported. The S N Ar and Buchwald–Hartwig cross‐coupling reactions were investigated to access C‐2 aminated imidazo[1,2‐ b ][1,
Buron, Frédéric +11 more
core +1 more source
Acta Crystallographica Section E, 2012 2,5-Bis(pyridin-2-yl)-1,3,4-thiadiazole (denoted L) has been found to act as a bidentate ligand in the monomeric title complex, [Cu(CF3O3S)(C12H8N4S)2(H2O)](CF3O3S). The complex shows a distorted octahedrally coordinated copper(II) cation which is linked
Fouad Bentiss +4 more
doaj +1 more source
Synthesis, Characterization and Docking Study of Novel Pyrimidine Derivatives as Anticancer Agents
Indonesian Journal of Chemistry, 2020 New compounds 5 and 9 using DNA bases e.g. Adenine 1 and Guanine 6 derivatives have been synthesized. The use of simple methods to synthesize compounds 5 and 9 were done using pyrimidine as an alternative DNA base ring.
Manal Mohamed Talaat El-Saidi +5 more
doaj +1 more source
Real‐Time Neurochemical Sensing in Zebrafish: Electrochemical and Fluorescent Approaches
Analysis &Sensing, Volume 6, Issue 6, November 2026.The use of zebrafish has emerged as a powerful approach for real‐time neurochemical measurements. This review highlights recent advances in electrochemical and fluorescent sensing strategies that enable dynamic measurements in live preparations of this complex vertebrate. These complementary approaches provide new insights into neurochemical signaling,
Piyanka Hettiarachchi +2 more
wiley +1 more source
Multitarget Drug Design for Cardiovascular Disease: Bridging Chemistry and Medicine
ChemMedChem, Volume 21, Issue 19, 14 October 2026.Many pathophysiological pathways associated with cardiovascular diseases involve multiple drug targets. This article reviews recent advances in the development of pharmacological compounds capable of simultaneously modulating multiple mechanisms. Multitarget drugs offer a promising therapeutic approach for complex cardiovascular disorders, including ...
Gyuzel Y. Mitronova +3 more
wiley +1 more source
SYNTHESIS AND ANTIMICROBIAL ACTIVITY OF SOME (2-AMINO-5-THIOL-1, 3, 4-THIADIAZOLE DERIVATIVES
مجلة بغداد للعلوم, 2007 Five derivatives of thiadiazole were prepared with aldehydes and alkyl halides, compoundA: 2-amino-5-thiol-1,3,4- thiadiazole, compound B :2-(o-hydroxybenzylidine)amino-5-thiol-1,3,4-thiadiazole, compoundC: 2(2-butan-lidine)amino-5-thiol-1,3,4 ...
Baghdad Science Journal
doaj +1 more source
Synthesis of π-Extended Thiadiazole (Oxides) and Their Electronic Properties
, 2016 The syntheses of extended thiadiazole, thiadiazole oxide, and thiadiazole dioxide heterocycles are described. The electron-accepting heterocycles were investigated by X-ray crystallography and optical as well as electrochemical measurements and supported
Thomas Linder (2259202) +3 more
core +2 more sources
[O─I─O]+ Halogen‐Bonded Complexes of Pyridine N‐Oxides
Angewandte Chemie, Volume 138, Issue 40, 28 September 2026.The missing puzzle of 3‐center‐4‐electron halogen‐bonded complexes viz. [O─I─O]+ of pyridine N‐oxides are structurally characterized by x‐ray diffraction. Monodentate N‐oxide O‐atom acts as the halogen bond acceptor. Their solution complexations are characterized by 15N NMR spectroscopy.
Rakesh Puttreddy +3 more
wiley +2 more sources