Results 101 to 110 of about 10,659 (219)

Biological Potential of Substituted Thiadiazole Compounds [PDF]

, 2015
Heterocyclic compounds are present in most biologically active molecules. The chemistry of heterocyclic compounds has been an interesting field of study.
Asif, Mohammad
core  

Computational Screening and Synthesis of Some Isatin-Thiadiazole Hybrids Potentially Targeting Diabetes

Chemistry Proceedings
This study explores the design, synthesis and preliminary in silico screening of novel thiadiazole-isatin hybrid derivatives targeting diabetes mellitus.
Monika, Nishtha Shalmali, Priyanshu
doaj   +1 more source

Synthesis and Antimicrobial Activity of Some 2-[(4-Substituted-Phenyl-3-Chloro-Azetidin-2-One)-5-(2'-Methylamino-4-Phenyl-1', 3'-Thiazolyl-]-1, 3,4-Thiadiazoles [PDF]

Journal of Sciences, Islamic Republic of Iran, 2009
A new 2-[(4-substituted-phenyl-3-chloroazetidin-2-one)-5-(2'-methylamino 4-phenyl-1', 3'-thiazolyl-]-1, 3, 4-thiadiazoles, 5(a-n) were synthesized from 2-substituted-benzylideneamino-5-[2'-methylamino-4'-phenyl-1',3'-thiazolyl]-1,3, 4-thiadiazole, 4(a-n)
S.D. Srivastava
doaj  

Functionalization of 2-Mercapto-5-methyl-1,3,4-thiadiazole: 2-(ω-Haloalkylthio) Thiadiazoles vs. Symmetrical Bis-Thiadiazoles

Molecules
A study on the functionalisation of 2-mercapto-5-methyl-1,3,4-thiadiazole has been conducted, yielding two series of products: 2-(ω-haloalkylthio)thiadiazoles and symmetrical bis-thiadiazoles, with variable chain lengths. The experimental conditions were optimised for each class of compounds by altering the base used and the reagents’ proportions ...
Zhanina S. Petkova, Rusi I. Rusew, Boris L. Shivachev, Vanya B. Kurteva   +3 more
openaire   +3 more sources

1,3,4-THIADIAZOLE: A BIOLOGICALLY ACTIVE SCAFFOLD [PDF]

, 2014
There has been considerable interest in the development of novel compounds with anticonvulsant, antidepressant, analgesic, anti-inflammatory, anti allergic, antipsychotic, antimicrobial, antimycobecterial, antitumour, antiviral and antitubercular ...
Akhtar, Jawed, Osman, Gamal, Khalilullah, Habibullah, Mhmood, Danish, Khan, M. U.   +4 more
core   +1 more source

The Activity of a Thiadiazole on Mycobacterium leprae

Experimental Biology and Medicine, 1976
SummaryA new broad-spectrum antimicrobial, 2-amino-5-(l-methyl-5-nitro-2-imi-dazolyl)-1,3,4-thiadiazole, reported inactive against Mycobacterium tuberculosis, inhibited multiplication of M. leprae in the mouse foot pad when administered orally to the mice.
openaire   +2 more sources

A Concise chemical and biological potential of thiadiazole analogues [PDF]

, 2014
The thiadiazole is one of the most important and well-known five-membered heterocyclic nuclei, which is a common and integral feature of a variety of natural products and medicinal agents.
Asif, Mohammad
core   +1 more source

The synthesis of 5-Phenyl-1,2,4-thiadiazole [PDF]

, 2001
Various attempts to determine the cause of an oxadiazole side product during the synthesis of 5-phenyl-1,2,4-thiadiazole were conducted, and experiments were used to either prove or disprove the theorized causes.
Denham, Rebecca April
core  

Synthesis of Mesoionic 1,3,4-Thiadiazole-2-Thiolates [PDF]

A reliable synthesis of C5-unsubstituted 1,3,4-thiadiazole-2-thiolates is described that avoids potentially explosive or laborious steps. This work presents a reliable method for preparing the starting material dithioformate from carbon disulfide and ...
Andreas Schmidt, Sean Ray Kahnert
core   +1 more source

Thiadiazoles. III*. Some 5-Substituted Derivatives of 2-Amino-1,3,4-Thiadiazoles and Some Mesoionic 1,3,4-Thiadiazoles

Croatica Chemica Acta, 1971
New derivatives of 1,3,4-thiadiazoles with potential phytohormonic (compds. I-V) and antibacterial (compds. VI-IX) activity have been prepared. Mesoionic structure of the compounds VI- IX is indicated by their IR and UV spectra.
Kuftinec, J., Kolbah, D.
openaire   +2 more sources