Results 101 to 110 of about 11,765 (225)
, 2008 In this study, we have synthesized several compounds and examined their cytotoxic effects on human non-small cell lung cancer A549 cells. We found that GO-13 ((EE)-2,5-bis[4- (3-dimethyl-aminopropoxy)styryl]-1,3,4- thiadiazole) is the most effective one ...
LAI, SHIN-YU;PAN, SHIOW-LIN;JOW, GUEY-MEI;CHERN, JI-WANG;GUH, JIH-HWA +1 more
core
Synthesis and Antimicrobial Activity of Some 2-[(4-Substituted-Phenyl-3-Chloro-Azetidin-2-One)-5-(2'-Methylamino-4-Phenyl-1', 3'-Thiazolyl-]-1, 3,4-Thiadiazoles [PDF]
Journal of Sciences, Islamic Republic of Iran, 2009 A new 2-[(4-substituted-phenyl-3-chloroazetidin-2-one)-5-(2'-methylamino 4-phenyl-1', 3'-thiazolyl-]-1, 3, 4-thiadiazoles, 5(a-n) were synthesized from 2-substituted-benzylideneamino-5-[2'-methylamino-4'-phenyl-1',3'-thiazolyl]-1,3, 4-thiadiazole, 4(a-n)
S.D. Srivastava
doaj
Various carbonic anhydrase (CA) enzyme isoforms are known today. In addition to the use of CA inhibitors as diuretics, antiepileptics and antiglaucoma agents, the inhibition of other specific isoforms of CA was reported to have clinical benefits in ...
Cüneyt Türkeş (10751831) +6 more
core +1 more source
, 2016 A series of organotin 4-methyl-1,2,3-thiadiazole-5-carboxylates and benzo[1,2,3]thiadiazole-7-carboxylates have been synthesized and characterized by NMR (1H, 13C, and 119Sn), IR, and elemental analyses.
Jun Zhang (48506) +5 more
core +1 more source
Chemistry ProceedingsThis study explores the design, synthesis and preliminary in silico screening of novel thiadiazole-isatin hybrid derivatives targeting diabetes mellitus.
Monika, Nishtha Shalmali, Priyanshu
doaj +1 more source
A Concise chemical and biological potential of thiadiazole analogues [PDF]
, 2014 The thiadiazole is one of the most important and well-known five-membered heterocyclic nuclei, which is a common and integral feature of a variety of natural products and medicinal agents.
Asif, Mohammad
core
The synthesis of 5-Phenyl-1,2,4-thiadiazole
, 2001 Various attempts to determine the cause of an oxadiazole side product during the synthesis of 5-phenyl-1,2,4-thiadiazole were conducted, and experiments were used to either prove or disprove the theorized causes.
Denham, Rebecca April
core +3 more sources
, 2019 New 1,3,4-thiadiazole thioglycosides linked to substituted arylidine systems were synthesized via glycosylation of the prepared 1,3,4-thiadiazole thiol compounds.
Hanem M. Awad +4 more
core +1 more source
THE SYNTHESIS OF NEW 1,2,3-THIADIAZOLE DERIVATIVES
, 1970 The reactions of 1,2,3-thiadiazole-4-carbonyl chloride with the appropriate amines led to formation of the following amides in good yield: N-ethyl-1,2,3-thiadia- zole-4-carboxamide; N-methyl-1,2,3-thiadiazole-4-carbox- amide; N-cyclohexyl-1,2,3 ...
PATTERSON, RONALD BRINTON
core
MoleculesMDM2 and MDM4 are major negative regulators of tumor suppressor p53. Beyond regulating p53, MDM2 possesses p53-independent activity in promoting cell cycle progression and tumorigenesis via its RING domain ubiquitin E3 ligase activity. MDM2 and MDM4 form
Rati Lama +7 more
doaj +1 more source