Results 31 to 40 of about 11,765 (225)

DataSheet1_Molecular iodine-promoted oxidative cyclization for the synthesis of 1,3,4-thiadiazole-fused- [1,2,4]-thiadiazole incorporating 1,4-benzodioxine moiety as potent inhibitors of α-amylase and α-glucosidase: In vitro and in silico study.PDF

, 2022
Twenty-five analogs were synthesized based on 1,3,4-thiadiazole-fused-[1,2,4]-thiadiazole incorporating 1,4-benzodioxine moiety (1–25) and then tested for the antidiabetic profile. The entire afforded derivatives showed varied inhibition profiles ranging
Eslam B. Elkaeed (9952518), Mazloom Shah (13798288), Wajid Rehman (5348324), Liaqat Rasheed (13913016), Shahid Iqbal (5632475), Haseena Naz (13913019), Rafaqat Hussain (12305506), Shoaib Khan (776422), Hanan A. Al-ghulikah (13913022), Rami Adel Pashameah (13201722), Eman Alzahrani (8779133), Abd-ElAziem Farouk (9338516)   +11 more
core   +1 more source

Synthesis and properties of some S-derivatives of 4-phenyl-5-((5-phenylamino-1,3,4-thiadiazole-2-ylthio)methyl)-1,2,4-triazole-3-thione

Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2019
Studies in the field of chemistry and pharmacology of derivatives of thiadiazole and 1,2,4-triazole are promising and relevant, which is associated with significant success in creating new drugs based on them. The combination of these heterocycles in one
A. S. Hotsulia, S. O. Fedotov
doaj   +1 more source

3-Benzhydryl-1,3,4-thiadiazole-2(3H)-thione [PDF]

, 2013
In the title compound, C15H12N2S2, the two phenyl rings and the planar (r.m.s. deviation = 0.002 Å) thiadiazole ring adopt a propeller conformation about the central C—H axis with H—C—C—C(phenyl) torsion angles of 44 ...
T. Thornton, Megan, Healy, Peter, Thornton, MT, Healy, PC, C. Henderson, Luke, Henderson, Luke, Peter C. Healy, Luke C. Henderson, Thornton, Megan, Megan T. Thornton, Henderson, LC   +10 more
core   +2 more sources

trans-Diaquabis[2,5-bis(pyridin-2-yl)-1,3,4-thiadiazole]nickel(II) bis(tetrafluoridoborate)

Acta Crystallographica Section E, 2011
The bidentate 1,3,4-thiadiazole ligand, namely, 2,5-bis(2-pyridyl)-1,3,4-thiadiazole (denoted L), untested as a polydentate ligand, has been found to form the monomeric title complex, [Ni(C12H8N4S)2(H2O)2](BF4)2.
Fouad Bentiss, Frédéric Capet, Michel Lagrenée, Mohamed Saadi, Lahcen El Ammari   +4 more
doaj   +1 more source

Synthesis, Anticancer Activity and Carbonic Anhydrase Inhibitory Activity of new Thiadiazole-hydrazone Derivatives

Cumhuriyet Science Journal, 2023
In five steps, new compounds 5a, 5b of thiadiazole-hydrazone derivatives were synthesized. Various spectral methods, such as 1H NMR, 13C NMR, and elemental analyses, were used to clarify the structures of the compounds. Three cancer cell lines (MCF7, MDA,
Ulviye Acar Çevik, Hayrani Eren Bostancı   +1 more
doaj   +1 more source

thiadiazole)-4-carbonitrile

, 2023
Electron-withdrawing heterocyclic units are found in most organic optoelectronic materials. Benzo[1,2-d:4,5-d′]bis([1,2,3]thiadiazole) is an interesting new heterocyclic system, the chemical properties of which are much less studied than other fused ...
Timofey A. Kudryashev, Oleg A. Rakitin, Karim S. Gaisin, Timofey N. Chmovzh   +3 more
core   +1 more source

New Route Synthesis of Thiadiazoles, Bisthiadiazoles, Thiadiazolotriazines, and Pyrazolothiadiazoles Based on Hydrazonoyl Halides and Dihydrazinylthiadiazole

Molecules, 2017
Synthesis and characterization of new thiadiazoles, bisthiadiazoles from the reaction of mono- and di-hydrazonoyl halides with various hydrazinecarbodithioate derivatives were studied.
Abdelwahed R. Sayed, Shar Saad Al-Shihry
doaj   +1 more source

Open‐Shell Conjugated Polymers Enable Photothermoelectric Conversion and Detection of Short‐Wave Infrared Light

Advanced Science, EarlyView.
Efficient conversion and detection of short‐wave infrared (SWIR) photons are becoming increasingly important for emerging photonic and energy technologies. Here, we report an organic photothermoelectric device based on an open‐shell conjugated polymer that enables SWIR energy conversion and photon detection via the photothermoelectric effect.
Guan‐Lin Chen, Soonyong Lee, Shao‐Huan Hong, Jhih‐Min Lin, Han Young Woo, Cheng‐Liang Liu   +5 more
wiley   +1 more source

Synthesis and Evaluation of the Anti-Microbial Activity of New Heterocycles Containing the 1,3,4-Thiadiazole Moiety

Molecules, 2011
A new series of thiadiazole-enaminones 4 were synthesized via reactions of 5-acetyl-1,3,4-thiadiazoles 3 with dimethylformamide-dimethylacetal (DMF-DMA).
Thoraya A. Farghaly, Zienab A. Muhammad, Magda A. Abdallah   +2 more
doaj   +1 more source

Antifungal Activity, Cytotoxicity and Mechanism of Action of Nitroheteroaryl-1,3,4-thiadiazole Containing N-benzyl and N-methoxyethyl Substitution Against Aspergillus fumigatus

Mediterranean Journal of Infection, Microbes and Antimicrobials, 2021
Introduction: This study aimed to evaluate antifungal activity and cytotoxicity of two new nitroheteroaryl-1,3,4-thiadiazole derivatives containing N-methoxyethyl (9) and N-benzyl (10) moiety against Aspergillus fumigatus with a special focus on their ...
Pegah MORADABAD, Azar TAHGHIGHI, Leili JALILI-BALEH, Alireza FOROUMADI, Masoomeh SHAMS-GHAHFAROKHI, Mehdi RAZZAGHI-ABYANEH   +5 more
doaj   +1 more source