Results 41 to 50 of about 10,659 (219)
Antifungal Activity of Novel Indole Derivatives Containing 1,3,4-Thiadiazole [PDF]
In this study, 24 indole derivatives containing 1,3,4-thiadiazole were discovered and synthesized. The target compounds’ antifungal efficacy against 14 plant pathogenic fungal pathogens was then determined in vitro.
Bangcan He (18452570) +8 more
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Molecules, 2017 Synthesis and characterization of new thiadiazoles, bisthiadiazoles from the reaction of mono- and di-hydrazonoyl halides with various hydrazinecarbodithioate derivatives were studied.
Abdelwahed R. Sayed, Shar Saad Al-Shihry
doaj +1 more source
Cumhuriyet Science Journal, 2023 In five steps, new compounds 5a, 5b of thiadiazole-hydrazone derivatives were synthesized. Various spectral methods, such as 1H NMR, 13C NMR, and elemental analyses, were used to clarify the structures of the compounds. Three cancer cell lines (MCF7, MDA,
Ulviye Acar Çevik +1 more
doaj +1 more source
Dual‐Module Near‐Infrared Fluorophores Discovery System via Knowledge Transfer
Advanced Science, EarlyView.This study presents a dual‐module deep learning system for the design of near‐infrared (NIR) fluorophores. A large molecular library is generated and analyzed, leading to the suggestions of promising candidates. The effectiveness of the system is further validated through the synthesis, characterization, and in vivo imaging, demonstrating its potential
Yixin Zhu +7 more
wiley +1 more source
, 2015 International audienceAbstract An original and efficient palladium‐catalyzed amination of imidazo[2,1‐ b ][1,3,4]thiadiazole is reported. The S N Ar and Buchwald–Hartwig cross‐coupling reactions were investigated to access C‐2 aminated imidazo[1,2‐ b ][1,
Buron, Frédéric +11 more
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Molecules, 2011 A new series of thiadiazole-enaminones 4 were synthesized via reactions of 5-acetyl-1,3,4-thiadiazoles 3 with dimethylformamide-dimethylacetal (DMF-DMA).
Thoraya A. Farghaly +2 more
doaj +1 more source
DFT calculation of the electronic properties of fluorene-1,3,4-thiadiazole oligomers [PDF]
, 2013 Thiadiazole derivatives have been widely employed in the areas of pharmaceutical, agricultural, industrial, and polymer chemistry. The electronic and molecular structures of thiadiazoles are of interest because they have an equal number of valence ...
NORMA ROSARIO FLORES HOLGUIN
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Mediterranean Journal of Infection, Microbes and Antimicrobials, 2021 Introduction: This study aimed to evaluate antifungal activity and cytotoxicity of two new nitroheteroaryl-1,3,4-thiadiazole derivatives containing N-methoxyethyl (9) and N-benzyl (10) moiety against Aspergillus fumigatus with a special focus on their ...
Pegah MORADABAD +5 more
doaj +1 more source
Discovery of CRBN‐based molecular glue degraders targeting WIZ transcription factor
Bulletin of the Korean Chemical Society, EarlyView.This work reports the discovery of 9l, a novel cereblon‐based molecular glue degrader which targets the WIZ transcription factor. Compound 9l facilitates WIZ‐CRBN ternary complex formation to degrade WIZ, subsequently inducing γ‐globin expression in HUDEP‐2 cells and highlighting its potential as a sickle cell disease therapy.
Tae‐Jun Kim +8 more
wiley +1 more source
Synthesis of Thiadiazole Zineb [PDF]
, 2011 In this paper, a series of 2-amino-5-alkyl-1, 3, 4-thiadiazole zineb were prepared by reacting 2-amino-5-alkyl-1, 3, 4-thiadiazole, CS2 and ZnCl2. Its synthesis conditions was discussed.
baojun, Su +3 more
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