Results 11 to 20 of about 65,595 (300)
Clinical Medicine Insights: Endocrinology and Diabetes, 2014 Thiamine deficiency has been documented to be prevalent in patients with diabetes mellitus, and correction of thiamine deficiency in this population may provide beneficial effects in several cardiometabolic parameters, including prevention of impending ...
Omar Al-Attas +5 more
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Quantitative analysis of oxidized vitamin B1 metabolites generated by hypochlorous acid [PDF]
, 2020 Thiamine, a water-soluble essential vitamin known as vitamin B1, acts as an important cofactor in various cellular processes, such as metabolism and energy production. Thiamine is also thought to have antioxidant effects as a singlet oxygen scavenger and
Uchida, Koji +3 more
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Glucose-induced down regulation of thiamine transporters in the kidney proximal tubular epithelium produces thiamine insufficiency in diabetes [PDF]
, 2012 Increased renal clearance of thiamine (vitamin B1) occurs in experimental and clinical diabetes producing thiamine insufficiency mediated by impaired tubular re-uptake and linked to the development of diabetic nephropathy.
Larkin James R. +22 more
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Inhibition of Thiamine Diphosphate (ThDP)-dependent Enzymes by Triazole-based Thiamine Analogues
, 2023 Thiamine (vitamin B1) is metabolised into the coenzyme thiamine diphosphate (ThDP). Interrupting thiamine-utilisation leads to disease states and thiamine/ThDP analogues are commonly used as antagonists of thiamine-utilisation pathways to investigate the
Finian James, Leeper +5 more
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BMC Chemistry, 2021 Thiamine (vitamin B1) is an essential micronutrient in the human diet, found both naturally and as a fortification ingredient in many foods and supplements.
Adrienne L. Voelker +2 more
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Severe thiamine deficiency in eastern Baltic cod (Gadus morhua).
PLoS ONE, 2020 The eastern Baltic cod (Gadus morhua) population has been decreasing in the Baltic Sea for at least 30 years. Condition indices of the Baltic cod have decreased, and previous studies have suggested that this might be due to overfishing, predation, lower ...
Josefin Engelhardt +6 more
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Open-chain thiamine analogues as potent inhibitors of thiamine pyrophosphate (TPP)-dependent enzymes
, 2023 A common approach to studying thiamine pyrophosphate (TPP)-dependent enzymes is by chemical inhibition with thiamine/TPP analogues which feature a neutral aromatic ring in place of the positive thiazolium ring of TPP.
Finian James, Leeper +2 more
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Application of Fe3O4/thiamine Magnetic Particles in the Removal of Methylene Blue
Applied Environmental Research, 2023 Fe3O4/thiamine particles were prepared in this work via precipitation method. The synthesis method is based on the principle of precipitation of Fe3O4 particles in the presence of thiamine coating agent.
Lan Tran-Nguyen +8 more
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Metabolites, 2023 The Thiamine Transporter 2 (THTR2) encoded by SLC19A3 plays an ill-defined role in the maintenance of tissue thiamine, thiamine monophosphate, and thiamine diphosphate (TDP) levels. To evaluate the impact of THTR2 on tissue thiamine status and metabolism,
Anita Wen +6 more
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EFSA Journal, 2011 Thiamine mononitrate administered via feed and thiamine hydrochloride via water for drinking are safe for the target animals having a wide margin of safety.
EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP)
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