Results 81 to 90 of about 60,963 (256)
Background: Micronutrients can benefit patients with heart failure (HF). Thiamine is a critical vitamin, while the impact of thiamine supplementation on patients with HF remains unclear.
Mengqi Xu+5 more
doaj
Management of xylazine toxicity, overdose, dependence, and withdrawal: A systematic review
Abstract Background and Objectives Xylazine, an alpha‐2‐adrenergic agonist, has been increasingly implicated in substance use and overdose crises. However, little is known about its effects on humans. With the growing public health crisis surrounding xylazine, it has become important to recognize and promptly manage symptoms of xylazine toxicity ...
Philipa Owusu‐Antwi+4 more
wiley +1 more source
Engineering of the Thiamine Diphosphate-Dependent JanthE for the Synthesis of Tertiary Alcohols. [PDF]
The synthesis of chiral tertiary alcohols is in high demand. Here we investigate in detail the aldehyde–ketone cross‐coupling reactions catalyzed by the promising thiamine diphosphate‐dependent lyase JanthE. Focusing on both reaction parameters and engineering, we rationally develop JanthE to improve its applicability and demonstrate its evolvability ...
Lanza L+7 more
europepmc +2 more sources
Summary Introduction Patients living with obesity present specific challenges for airway management. They have been overrepresented repeatedly in studies looking at complications associated with airway management. Whilst generic airway guidelines offer assistance, there are no evidence‐based guidelines specific to this group of patients to support safe
Andrew McKechnie+7 more
wiley +1 more source
When, which and how to switch: Navigating JAK inhibitors in myelofibrosis
Navigating choice of JAK inhibitor (JAKi) therapy for patients with myelofibrosis who are JAKi‐naïve and for those who have previously been treated with a JAKi.
Jennifer O'Sullivan+2 more
wiley +1 more source
British Thyroid Association Survey of Graves' Disease Management in the UK
ABSTRACT Background Recent years have seen changes and uncertainties in evidence and guideline recommendations in Graves' disease treatment. To understand the impact of these developments on current practice, we undertook a survey of Graves' disease management in the United Kingdom and compared this to other national and international surveys.
Michael Atkinson+5 more
wiley +1 more source
Thiamine serves as a cofactor of key enzymes involved in glucose metabolism, and its regulatory role in high-carbohydrate diet has not been reported in crustaceans.
Yonghui Jian+8 more
doaj
Thiamine-responsive megaloblastic anemia: early diagnosis may be effective in preventing deafness
Thiamine-responsive megaloblastic anemia syndrome is an autosomal recessive disorder characterized by diabetes mellitus, megaloblastic anemia and sensorineural hearing loss.
Hasan Onal+7 more
doaj
Thiamine deficiency after feeding pyrithiamine [PDF]
J C Koedam+2 more
openalex +1 more source
ABSTRACT Introduction Kava is a plant‐based drug central to many Pacific Island cultures, yet its physiological and psychological effects remain contested and poorly understood. Additionally, the broader social, economic, and policy consequences of kava trade and consumption are unclear.
George Economidis+7 more
wiley +1 more source