A competitive lateral flow immunoassay (LFA) using fluorescent microspheres (FMs) as label was developed for the quantitative detection of chloramphenicol (CAP), thiamphenicol (TAP) and florfenicol (FF) in milk.
Jianyi Wang +2 more
exaly +2 more sources
Distribution and Probabilistic Risk Assessment of Antibiotics, Illegal Drugs, and Toxic Elements in Gastropods from Southeast China [PDF]
We investigated fourteen antibiotics, three illegal drugs, and two toxic elements in commercially available gastropods from southeast China. The data revealed high detection frequencies (DFs) for florfenicol (61.32%), florfenicol amine (47.33%), and ...
Hai-Tao Shen +2 more
doaj +2 more sources
Hospital-Associated Antimicrobial Resistant Bacteria on 95 Mobile Phones: An International Metagenomic "Phonome" Analysis. [PDF]
On average, phones harbored 3.62 of the top 10 killers and 2.49 ESKAPE organisms. In total, 667 VFGs (8621 Hits) and 262 ARGs (2475 Hits) were identified on 95 mobile phones. Mobile phones serve as a platform for horizontal gene transfer and AMR development.
Goldsworthy A +12 more
europepmc +2 more sources
In vitro activity of thiamphenicol against Haemophilus influenzae, Streptococcus pneumoniae and Streptococcus pyogenes clinical isolates [PDF]
Objective. To determine in vitro activity of thiamphenicol and other clinically available antimicrobials against clinical isolates of Haemophilus influenzae, Streptococcus pneumoniae and Streptococcus pyogenes. Materials and Methods.
Ivanchik N.V. +5 more
doaj +1 more source
Expanded Functional Characterization and Optimization of Protein Expression in Treponema denticola Shuttle Plasmids. [PDF]
We report optimization of the Treponema denticola shuttle plasmid system by minimizing its size and by characterizing an array of promoter‐gene constructs for genetic complementation, including the first use in Treponema of a Tet‐inducible system for controlled expression of potentially toxic genes.
Goetting-Minesky MP +8 more
europepmc +2 more sources
The Streptomyces Metabolite Thiostrepton Inhibits Regulatory T Cell Differentiation and Function to Boost Antitumor Immune Responses. [PDF]
Regulatory T cells (Tregs) promote tumor progression and therapy resistance by suppressing antitumor immunity. Here, we identify the antibiotic thiostrepton as a novel Treg‐targeting immunomodulator for cancer immunotherapy. Thiostrepton impairs Treg differentiation and suppressive capacity. In an MC38 model, thiostrepton treatment reduced intratumoral
Silva L +9 more
europepmc +2 more sources
Topical antibiotics for acute rhinosinusitis in children
The authors presented an overview of the existing data on inhalation therapy with antibacterial drugs in acute rhinosinusitis and exacerbation of chronic rhinosinusitis in children.
E. P. Karpova +2 more
doaj +1 more source
PHARMACOKINETICS AND BIOAVAILABILITY OF THIAMPHENICOL GLYCINATE HCL IN MALE GOATS [PDF]
The Pharmacokinetic profile of thiamphenicol glycinate HCl wasstudied in male goats following single intravenous and intramuscularadministration of 30 mg kg-1 b.wt.
M. A. Tohamy, A. H. Bogzil
doaj +1 more source
Inhaled antibacterial drugs have been used since the 1940s with greater or lesser effectiveness, due to the possibility of targeted delivery of drugs directly to the infection site at concentrations higher than MICs.
Vladimir N. Drozdov +7 more
doaj +1 more source
Local antibiotic therapy options for treating acute rhinosinusitis in children
The article presents various types of acute rhinosinusitis progression in pediatric practice depending on the duration of the disease, based on the available modern consensus papers and clinical guidelines.
S. A. Karpishchenko +2 more
doaj +1 more source

