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Thiazole-Mediated Synthetic Methodology

open access: yesChemical Reviews, 2004
Review of synthetic schemes which have been developed in about 20 years of research by the use of thiazole-based methodology may serve to illustrate the potential of this approach in synthetic programs toward the construction of complex systems or special molecular fragments.
DONDONI, Alessandro, MARRA, Alberto
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The Thiazole Aldehyde Synthesis

open access: yesSynthesis, 1998
Aldehydes with diverse structural arrays are prepared by construction of carbon chains at C-2 of the thiazole ring and conversion of the heterocycle into the formyl group. Various methods are described that differ depending on the type of thiazole-based reagent employed in the initial carbon-carbon bond forming reaction leading to 2-substituted ...
DONDONI, Alessandro, Alessandro Dondoni
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Thiazoles

ChemInform, 2003
AbstractFor Abstract see ChemInform Abstract in Full Text.
D. Kikelj, U. Urleb
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Antiprotozoal thiazoles. 2-(5-Nitro-2-thienyl)thiazoles

Journal of Medicinal Chemistry, 1975
A series of 2-(5-nitro-2-thienyl)thiazoles and their vinylogs having substituted methylamine side chains has been prepared by halogen displacement on the corresponding 4-chloromethylthiazole. Of these, 4-morpholinomethyl-2-(5-nitro-2-thienyl)thiazole showed moderate activity against Trypanosoma cruzi and Trypanosoma rhodesiense in mice.
J P, Verge, P, Roffey
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Chemistry of the thiazoles

Proceedings of the Indian Academy of Sciences - Section A, 1953
Chrysean has been isolated in two forms; whether they are stereosoimers or only dimorphic forms is discussed. A mechanism of formation of chrysean is suggested. With methyl iodide it gives readily the S-methyl derivative which reacts easily with aniline,p-chloraniline andm-aminophenol to furnish the amidino derivatives of formula (IX).
K. Ganapathi, K. D. Kulkarni
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Direct Arylation of Thiazoles on Water

Angewandte Chemie, 2007
Wetter is better: The direct arylation of thiazoles on water is quicker, cleaner, and higher-yielding than arylation in organic solvents. The reaction works under mild conditions for an array of aryl iodides, producing 2,5-diaryl thiazoles in excellent yields.
Turner, Gemma L.   +2 more
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Imidazole, oxazole and thiazole alkaloids

Natural Product Reports, 2006
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
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Thiazoles

2022
Agata Chotera-Ouda   +3 more
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Synthesis of Thiazoles from Metalated Thiazoles

2010
P. A. Koutentis, H. A. Ioannidou
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