Results 81 to 90 of about 15,973 (252)

Safety evaluation of substituted thiophenes used as flavoring ingredients. [PDF]

, 2016
This publication is the second in a series by the Expert Panel of the Flavor and Extract Manufacturers Association summarizing the conclusions of its third systematic re-evaluation of the safety of flavorings previously considered to be generally ...
Bastaki, M, Cohen, SM, Fukushima, S, Gooderham, NJ, Guengerich, FP, Harman, CL, Hecht, SS, McGowen, MM, Rietjens, IM, Smith, RL, Taylor, SV, Valerio, LG   +11 more
core   +1 more source

Bifunctional Photocatalysts: Exploiting Proximity for Enhanced Reaction Performance

Chemistry – A European Journal, EarlyView.
This review covers the application of the bifunctional approach to photocatalysis as a means to attain (enhanced) enantioselectivity, and, more in general, as a strategy to enhance the catalytic performance through an effective use of short‐lived reaction intermediates.
Luigi Dolcini, Daniele Lavelli, Alberto Dal Corso, Luca Pignataro   +3 more
wiley   +1 more source

Mild N‑Arylation of Sulfoximines With (Hetero)aryl Chlorides Enabled by α‐Methylnaphthyl‐tBuBrettPhos Palladium Triflate

Chemistry – A European Journal, EarlyView.
A readily accessible, air‐ and moisture‐stable palladium precatalyst, [Pd(1‐MeNAP)(tBuBrettPhos)]OTf, enables the direct N‐arylation of NH‐sulfoximines with (hetero)aryl chlorides under exceptionally mild conditions ideal for late‐stage diversification of drug‐like scaffolds.
Sourav Manna, Mahima Pilania, Kumarjit Sen, Nikolaos V. Tzouras, Angelino Doppiu, Lukas J. Gooßen   +5 more
wiley   +1 more source

Synthesis and Antithrombotic Activity Determination of (2-Methyl-4-[4-methyl-2-(4-trifluoromethylphenyl)-thiazole-5-ylmethylsulfanyl]phenoxy)acetic Acid Derivatives

Тонкие химические технологии, 2019
The article proposes an approach for obtaining the derivatives of hetarylmethylthioaryloxyalcane PPARS/fi agonists containing sulfoxide and sulfone fragments in the linker, the parent compound for the synthesis being GSK-516 - (2-methyl-4-[4-methyl-2-(4 ...
D. V. Minin, S. V. Popkov, M. L. Burdeyny, V. M. Goncharov, S. V. Vasilevsky   +4 more
doaj   +1 more source

Nickel‐Catalyzed Three‐Component Coupling Reactions of Iodobenzenes, an Isocyanide, and a Disilathiane: Access to Cyclic Thioimidates and Secondary Thioamides

European Journal of Organic Chemistry, EarlyView.
The one‐pot synthesis of 3‐benzylidenbenzo[c]thiophen‐1‐amines was achieved through the nickel‐catalyzed three‐component coupling reaction of 1‐ethynyl‐2‐iodobenzenes, tert‐butyl isocyanide, and hexamethyldisilathiane. This procedure is applicable to the preparation of secondary thioamides using aryl iodides.
Norio Sakai, Shun Nishitai, Reo Ikeda, Yohei Ogiwara, Kento Ishida   +4 more
wiley   +1 more source

Green synthesis of highly functionalized octahydropyrrolo[3,4-c]pyrrole derivatives using subcritical water, and their anti(myco)bacterial and antifungal activity [PDF]

, 2018
A series of novel 2-(thiazol-2-yl)-octahydropyrrolo[3,4-c]pyrroles was synthesized by reaction of octahydropyrrolo[3,4-c]pyrrole N-benzoylthiourea derivatives and α-haloketones in subcritical water at 130 °C in 75-91% yield.
De Coen, Laurens, Gemili, Muge, Nural, Yahya, Ulger, Mahmut, Yabalak, Erdal   +4 more
core   +1 more source

Recent advances in organic broad‐spectrum photodetection materials and devices

InfoMat, EarlyView.
Graphical Abstract This review systematically outlines the evolution of organic photodetectors from fullerene‐based to advanced non‐fullerene acceptors, highlighting how molecular engineering (e.g., D–A, quinoidal, and A‐D‐A′‐D‐A architectures) extends spectral response into the short‐wave infrared region.
Yilin Zhao, Shijia Tan, Deyang Ji, Wenping Hu   +3 more
wiley   +1 more source

An Organometallic [2]Catenane With Pt‒(di‐NHC)‒Pt Units: A Topology‐Driven Strategy for Enhanced Phosphorescence in Discrete Aggregates

Angewandte Chemie, Volume 138, Issue 19, 4 May 2026.
The mechanically interlocked Borromean rings are stabilized by π···π stacking interactions while the [2]catenane is stabilized by solvophobic effects. While the π···π interactions in the Borromean rings lead to severe luminescence quenching, the solvophobically assembled [2]catenane effectively circumvents these interactions, simultaneously restricting
Ye Lu, Xi‐Dong Wu, Zi‐Yan Min, Lu An, Shi‐Ping Yang, F. Ekkehardt Hahn   +5 more
wiley   +2 more sources

The Impact of Genetic Polymorphisms on Genotoxicity (DNA Damage) Among Children Exposed to Environmental Mutagens: A Systematic Review

Journal of Applied Toxicology, EarlyView.
ABSTRACT Children, as a particularly vulnerable group, are more susceptible to these mutagens due to their developing immune systems, higher physiological vulnerability, and increased exposure through behaviors like outdoor play and hand‐to‐mouth activities. This review aims to investigate the relationship between these environmental exposures, genetic
Thiago Guedes Pinto, Daniel Vitor de Souza, Gabriel Carvalhal de Aguiar, Ana Claudia Muniz Renno, Patricia Ramos Cury, Jean Nunes dos Santos, Rogerio Aparecido Dedivitis, Daniel Araki Ribeiro   +7 more
wiley   +1 more source

Synthesis and Antimicrobial Activity of Some New Thiadiazoles, Thioamides, 5-Arylazothiazoles and Pyrimido[4,5-d][1,2,4]triazolo[4,3-a]pyrimidines

Molecules, 2016
A novel series of 1,3,4-thiadiazoles, 5-arylazothiazoles and hexahydropyrimido-[4,5-d][1,2,4]triazolo[4,3-a]pyrimidines were synthesized via reaction of hydrazonoyl halides with each of alkyl carbothioates, carbothioamides and 7-thioxo-5,6,7,8 ...
Abdou O. Abdelhamid, Ibrahim E. El Sayed, Mohamed Z. Hussein, Mangoud M. Mangoud   +3 more
doaj   +1 more source