Results 1 to 10 of about 38,302 (143)

Thiazolidinedione Use and Cardiovascular Outcomes in Patients With Type 2 Diabetes Who Underwent Carotid Artery Revascularization [PDF]

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Thiazolidinediones are oral antidiabetic agents known for their wide‐ranging pleiotropic effects, potentially offering cardiovascular protection.
Jun Hwee Kim, Jimin Jeon, Seok‐Jae Heo, Tae‐Jin Song, Minyoul Baik, Joonsang Yoo, Jinkwon Kim   +6 more
doaj   +2 more sources

Combination of pioglitazone and dendritic cell to optimize efficacy of immune cell therapy in CT26 tumor models [PDF]

BioImpacts, 2023
Introduction: The maturation faith of dendritic cells is restrained by the inflammatory environment and cytokines, such as interleukin-6 and its downstream component. Therefore, introducing the suitable antigen to dendritic cells is crucial.
Samaneh Tokhanbigli, Helia Alavifard, Hamid Asadzadeh Aghdaei, Mohammad Reza Zali, Kaveh Baghaei   +4 more
doaj   +1 more source

Comparison of the Effects of Various Antidiabetic Medication on Bone Mineral Density in Patients with Type 2 Diabetes Mellitus [PDF]

Endocrinology and Metabolism, 2021
Background Prospective comparative studies on the effects of various antidiabetic agents on bone metabolism are limited. This study aimed to assess changes in bone mass and biochemical bone markers in postmenopausal patients with type 2 diabetes mellitus
Jeonghoon Ha, Yejee Lim, Mee Kyoung Kim, Hyuk-Sang Kwon, Ki-Ho Song, Seung Hyun Ko, Moo Il Kang, Sung Dae Moon, Ki-Hyun Baek   +8 more
doaj   +1 more source

Comparison of glucagon-like peptide-1 receptor agonists and thiazolidinediones on treating nonalcoholic fatty liver disease: A network meta-analysis [PDF]

Clinical and Molecular Hepatology, 2023
Background/Aims Previous studies have revealed that glucagon-like peptide-1 receptor agonist (GLP-1RA) and thiazolidinedione (TZD) can improve nonalcoholic fatty liver disease (NAFLD) or nonalcoholic steatohepatitis (NASH).
Min Jeong Park, Hayeon Kim, Myeong Gyu Kim, Kyungim Kim   +3 more
doaj   +1 more source

The Sex and Race Specific Relationship between Anthropometry and Body Fat Composition Determined from Computed Tomography: Evidence from the Multi-Ethnic Study of Atherosclerosis. [PDF]

, 2015
BackgroundFew studies have investigated the relationship of anthropometric measurements with computed tomography (CT) body fat composition, and even fewer determined if these relationships differ by sex and race.MethodsCT scans from 1,851 participants in
Allison, Matthew A, Anderson, Cheryl AM, Ding, Jingzhong, Golden, Sherita Hill, Mongraw-Chaffin, Morgana, Ouyang, Pamela, Schreiner, Pamela J, Szklo, Moyses, Woodward, Mark, Young, Jeffery Hunter   +9 more
core   +13 more sources

Thiazolidinedione Derivatives: In Silico, In Vitro, In Vivo, Antioxidant and Anti-Diabetic Evaluation

Molecules, 2022
This work aimed to synthesize a new antihyperglycemic thiazolidinedione based on the spectral data. The DFT\B3LYP\6-311G** level of theory was used to investigate the frontier molecular orbitals (FMOs), chemical reactivity and map the molecular ...
Manal Y. Sameeh, Manal M. Khowdiary, Hisham S. Nassar, Mahmoud M. Abdelall, Hamada H. Amer, Abdelaaty Hamed, Ahmed A. Elhenawy   +6 more
doaj   +1 more source

The Efficacy of Treatment Intensification by Quadruple Oral Therapy Compared to GLP-1RA Therapy in Poorly Controlled Type 2 Diabetes Mellitus Patients: A Real-world Data Study [PDF]

Diabetes & Metabolism Journal, 2023
We compared the glycemic efficacy of treatment intensification between quadruple oral antidiabetic drug therapy and once-weekly glucagon-like peptide-1 receptor agonist (GLP-1RA)-based triple therapy in patients with poorly controlled type 2 diabetes ...
Minyoung Kim, Hosu Kim, Kyong Young Kim, Soo Kyoung Kim, Junghwa Jung, Jong Ryeal Hahm, Jaehoon Jung, Jong Ha Baek   +7 more
doaj   +1 more source

Comparative efficacy of oral insulin sensitizers metformin, thiazolidinediones, inositol, and berberine in improving endocrine and metabolic profiles in women with PCOS: a network meta-analysis

Reproductive Health, 2021
Plain English summary This study aimed to compare the effects of oral insulin sensitizers on endocrine and metabolic profiles in women with polycystic ovary syndrome (PCOS). A random-effects network meta-analysis including 22 trials was conducted.
Han Zhao, Chuan Xing, Jiaqi Zhang, Bing He   +3 more
doaj   +1 more source

Comparative Effects of Sodium-Glucose Cotransporter 2 Inhibitor and Thiazolidinedione Treatment on Risk of Stroke among Patients with Type 2 Diabetes Mellitus [PDF]

Diabetes & Metabolism Journal, 2022
Background Although cardiovascular outcome trials using sodium-glucose cotransporter-2 inhibitors (SGLT-2i) showed a reduction in risk of 3-point major adverse cardiovascular events (MACE), they did not demonstrate beneficial effects on stroke risk ...
Seung Eun Lee, Hyewon Nam, Han Seok Choi, Hoseob Kim, Dae-Sung Kyoung, Kyoung-Ah Kim   +5 more
doaj   +1 more source

DPP4i, thiazolidinediones, or insulin and risks of cancer in patients with type 2 diabetes mellitus on metformin–sulfonylurea dual therapy with inadequate control

BMJ Open Diabetes Research & Care, 2020
Introduction This study aims to compare the risks of cancer among patients with type 2 diabetes mellitus (T2DM) on metformin–sulfonylurea dual therapy intensified with dipeptidyl peptidase 4 inhibitors (DPP4i), thiazolidinediones, or insulin.Research ...
Esther W Y Chan, Emily T Y Tse, Cindy L K Lam   +2 more
doaj   +1 more source