Results 61 to 70 of about 858,822 (287)

Thick composite design for hydrogen vessels: A contribution to composite design method [PDF]

open access: yesCIRP Annals, 2013
Abstract Hydrogen stock vessels add new product specifications because of higher pressure use. Today static application leads up to 700 bars. But pressure devices must resist, because of certification, at 3 times pressure (2100 bars). Composite vessels give material–structure potential solutions.
Perry, Nicolas   +4 more
openaire   +4 more sources

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Impact response and failure behavior of adhesive-bonded aluminum-wood lightweight composites

open access: yesJournal of Materials Research and Technology
Metal-wood composites are promising lightweight materials for substituting traditional steels or aluminum alloys in automotive applications. This study investigates the pendulum impact response of 4 mm-thick solid birch plates and laminates made of 1 mm ...
Eva Graf   +5 more
doaj   +1 more source

Effect of composition, viscosity and thickness of the opaquer on the adhesion of resin composite to titanium [PDF]

open access: yesDental Materials, 2009
OBJECTIVES: The objectives of this study were to determine the bond strength of powder-liquid and paste opaquers with different chemical compositions and viscosity to a metal substructure when they were applied in two thicknesses and to evaluate the failure modes after the bond strength test. METHODS: Titanium plates (51 mm x 25 mm x 1mm) (n(plates)=25,
Özcan, M, Kumbuloglu, O
openaire   +4 more sources

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Drape optimization in woven composites manufacture. [PDF]

open access: yes, 2005
This paper addresses the optimisation of forming in manufacturing of composites. A simplified finite element model of draping is developed and implemented.
Monroy, Aceves C.   +2 more
core   +3 more sources

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Thick Composite Structures under a Load Pinch [PDF]

open access: yesAdvanced Materials Research, 2015
Thick composites are increasingly used in the design of mechanical structures. Combined with low weight, they are generally resistant structures, which can support importante loads. In addition, depending on the number and nature of the materials used, it is possible to adapt properties for specific applications (damping structures).This work proposes ...
openaire   +3 more sources

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

Tailoring Dielectric Properties of Multilayer Composites Using Spark Plasma Sintering [PDF]

open access: yes, 2007
A straightforward and simple way to produce well-densified ferroelectric ceramic composites with a full control of both architecture and properties using spark plasma sintering (SPS) is proposed. SPS main outcome is indeed to obtain high densification at
Estournès, Claude   +2 more
core   +1 more source

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