Results 151 to 160 of about 125,465 (286)
Stress-dependent activation of myosin in the heart requires thin filament activation and thick filament mechanosensing. [PDF]
Proc Natl Acad Sci U S A, 2021 Park-Holohan SJ +5 more
europepmc +1 more source
A Non‐Reciprocal Architected Porous Medium
Advanced Functional Materials, EarlyView.ABSTRACT In several fluid flow, energy‐dumping, and energy‐harvesting applications, a dominant flow direction or dominant resistance direction is desirable. In this study, we propose a simple modular geometry that doubles flow resistance in one direction relative to the opposite direction, while maintaining laminar viscous flow.
Clément Vezies +2 more
wiley +1 more source
Construction of kinesin thick filament
Seibutsu Butsuri, 2003 T. Taba +5 more
openaire +1 more source
Advanced Functional Materials, EarlyView.This study demonstrates that memristors can replace conventional 2T–1C driving circuits with simplified 1T–1 m architectures by exploiting resistance switching. With ultra‐low switching voltages (< ±0.2 V) and multi‐level resistance states, the memristors precisely control the current injected into organic light‐emitting diodes (OLEDs).
Dong Hyun Kim +6 more
wiley +1 more source
Active Learning‐Accelerated Discovery of Fibrous Hydrogels with Tissue‐Mimetic Viscoelasticity
Advanced Functional Materials, EarlyView.Active learning accelerates the design of fibrous hydrogels that mimic the viscoelasticity of native tissues. By integrating multi‐objective optimization and closed‐loop experimentation, this approach efficiently identifies optimal formulations from thousands of possibilities and decouples elasticity and viscosity. The resulting hydrogels offer tunable
Zhengkun Chen +11 more
wiley +1 more source
Advanced Functional Materials, EarlyView.An original method is presented for producing artificial spider silk fibers with magnetic and magnetomechanical responsiveness, which consists in coating them with a nanometer‐thick layer of FeCo alloy by sputtering deposition. The challenge of combining organic materials and inorganic magnetic nanostructures is addressed, thus taking a step forward ...
Filippo Lanaro +5 more
wiley +1 more source
Advanced Healthcare Materials, EarlyView.Coagulative granular hydrogels are composed of packed thrombin‐functionalized microgels that catalyze the conversion of fibrinogen into a secondary fibrin network, filling the interstitial voids. This bio‐inspired approach stabilizes the biomaterial to match the robustness of bulk hydrogels without compromising injectability, mimicking the initial ...
Zhipeng Deng +16 more
wiley +1 more source
Aqueous Two‐Phase Bioinks for Discrete Packing and Compartmentalization of 3D Bioprinted Cells
Advanced Healthcare Materials, EarlyView.Aqueous two‐phase systems (ATPS) enable the formation of biomimetic interfaces crucial for tissue engineering. However, clinical translation remains limited by the challenge of precisely controlling cellular compartmentalization. Here, we developed ATPS biomaterial inks for 3D bioprinting allowing tuneable droplet formation via NaCl modulation.
Martina Marcotulli +17 more
wiley +1 more source
Advanced Healthcare Materials, EarlyView.We measure the cell‐specific responses of administering infusible ECM (iECM) in acute myocardial infarction (MI) across multiple timepoints. Using single‐nucleus RNA sequencing and spatial transcriptomics, we measure macrophage activation, fibroblast remodeling, increased vascular development, lymphangiogenesis, cardioprotection, and neurogenesis ...
Joshua M. Mesfin +18 more
wiley +1 more source
Fluid Forces Control Structural Remodeling of Blind‐Ended Lymphatic Microvessels
Advanced Healthcare Materials, EarlyView.Using innovative microfluidic biofabrication with fluid mechanical insights, we recapitulated the blind‐ended microanatomy and physiological drainage properties of capillary lymphatics. Our results reveal the interrelationship between intra‐ and extraluminal regions of lymphatic vessels due to flow‐induced sprouting and morphological changes that ...
Jacob C. Holter +5 more
wiley +1 more source