Results 1 to 10 of about 21,247 (241)
Isolation and Mechanical Measurements of Myofibrils from Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes [PDF]
Summary: Tension production and contractile properties are poorly characterized aspects of excitation-contraction coupling of human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs).
Josè Manuel Pioner +16 more
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Recurring adaptation effect on energy metabolism of atrophic shin muscles [PDF]
The article is devoted to recurring adaptation effect on energy metabolism of atrophic shin muscles. The purpose: Investigation of markers of activity of muscular fibers of gravitation-dependent muscles in condition of early posthypoki-netic readaptation.
Afanasyev М.А.
doaj
Lipid composition of heart muscle homogenate
Using cytochrome oxidase and esterase assays as a guide, mitochondria and microsomes were prepared from ox heart homogenate with about 25% cross-contamination of phospholipid.
L.W. Wheeldon, Z. Schumert, D.A. Turner
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Cooperation between myofibril growth and costamere maturation in human cardiomyocytes
Costameres, as striated muscle-specific cell adhesions, anchor both M-lines and Z-lines of the sarcomeres to the extracellular matrix. Previous studies have demonstrated that costameres intimately participate in the initial assembly of myofibrils ...
Huaiyu Shi +8 more
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Mechanobiology of muscle and myofibril morphogenesis
Muscles generate forces for animal locomotion. The contractile apparatus of muscles is the sarcomere, a highly regular array of large actin and myosin filaments linked by gigantic titin springs. During muscle development many sarcomeres assemble in series into long periodic myofibrils that mechanically connect the attached skeleton elements.
Luis, Nuno Miguel, Schnorrer, Frank
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Muscle weakness in corticosteroid myopathy is mainly the result of the destruction and atrophy of the myofibrillar compartment of fast-twitch muscle fibers.
Teet Seene, Priit Kaasik
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Tension-driven multi-scale self-organisation in human iPSC-derived muscle fibers
Human muscle is a hierarchically organised tissue with its contractile cells called myofibers packed into large myofiber bundles. Each myofiber contains periodic myofibrils built by hundreds of contractile sarcomeres that generate large mechanical forces.
Qiyan Mao +16 more
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Sarcomeres are the basic contractile units within cardiac myocytes, and the collective shortening of sarcomeres aligned along myofibrils generates the force driving the heartbeat.
Abigail C Neininger-Castro +7 more
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Myofibril diameter is set by a finely tuned mechanism of protein oligomerization in Drosophila
Myofibrils are huge cytoskeletal assemblies embedded in the cytosol of muscle cells. They consist of arrays of sarcomeres, the smallest contractile unit of muscles.
Nicanor González-Morales +5 more
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Myofibrils put the squeeze on nuclei [PDF]
During muscle development, nuclei travel from the centre of the myofibre to the periphery, a process defective in certain diseases. A new study reveals that this movement is due to centripetal forces imposed on nuclei by the crosslinking and contraction of myofibrils.
Jonathan N, Rosen, Mary K, Baylies
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