Results 1 to 10 of about 21,247 (241)

Isolation and Mechanical Measurements of Myofibrils from Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes [PDF]

open access: yesStem Cell Reports, 2016
Summary: Tension production and contractile properties are poorly characterized aspects of excitation-contraction coupling of human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs).
Josè Manuel Pioner   +16 more
doaj   +2 more sources

Recurring adaptation effect on energy metabolism of atrophic shin muscles [PDF]

open access: yesСаратовский научно-медицинский журнал, 2012
The article is devoted to recurring adaptation effect on energy metabolism of atrophic shin muscles. The purpose: Investigation of markers of activity of muscular fibers of gravitation-dependent muscles in condition of early posthypoki-netic readaptation.
Afanasyev М.А.
doaj  

Lipid composition of heart muscle homogenate

open access: yesJournal of Lipid Research, 1965
Using cytochrome oxidase and esterase assays as a guide, mitochondria and microsomes were prepared from ox heart homogenate with about 25% cross-contamination of phospholipid.
L.W. Wheeldon, Z. Schumert, D.A. Turner
doaj   +1 more source

Cooperation between myofibril growth and costamere maturation in human cardiomyocytes

open access: yesFrontiers in Bioengineering and Biotechnology, 2022
Costameres, as striated muscle-specific cell adhesions, anchor both M-lines and Z-lines of the sarcomeres to the extracellular matrix. Previous studies have demonstrated that costameres intimately participate in the initial assembly of myofibrils ...
Huaiyu Shi   +8 more
doaj   +1 more source

Mechanobiology of muscle and myofibril morphogenesis

open access: yesCells & Development, 2021
Muscles generate forces for animal locomotion. The contractile apparatus of muscles is the sarcomere, a highly regular array of large actin and myosin filaments linked by gigantic titin springs. During muscle development many sarcomeres assemble in series into long periodic myofibrils that mechanically connect the attached skeleton elements.
Luis, Nuno Miguel, Schnorrer, Frank
openaire   +2 more sources

Role of Myofibrillar Protein Catabolism in Development of Glucocorticoid Myopathy: Aging and Functional Activity Aspects

open access: yesMetabolites, 2016
Muscle weakness in corticosteroid myopathy is mainly the result of the destruction and atrophy of the myofibrillar compartment of fast-twitch muscle fibers.
Teet Seene, Priit Kaasik
doaj   +1 more source

Tension-driven multi-scale self-organisation in human iPSC-derived muscle fibers

open access: yeseLife, 2022
Human muscle is a hierarchically organised tissue with its contractile cells called myofibers packed into large myofiber bundles. Each myofiber contains periodic myofibrils built by hundreds of contractile sarcomeres that generate large mechanical forces.
Qiyan Mao   +16 more
doaj   +1 more source

Independent regulation of Z-lines and M-lines during sarcomere assembly in cardiac myocytes revealed by the automatic image analysis software sarcApp

open access: yeseLife, 2023
Sarcomeres are the basic contractile units within cardiac myocytes, and the collective shortening of sarcomeres aligned along myofibrils generates the force driving the heartbeat.
Abigail C Neininger-Castro   +7 more
doaj   +1 more source

Myofibril diameter is set by a finely tuned mechanism of protein oligomerization in Drosophila

open access: yeseLife, 2019
Myofibrils are huge cytoskeletal assemblies embedded in the cytosol of muscle cells. They consist of arrays of sarcomeres, the smallest contractile unit of muscles.
Nicanor González-Morales   +5 more
doaj   +1 more source

Myofibrils put the squeeze on nuclei [PDF]

open access: yesNature Cell Biology, 2017
During muscle development, nuclei travel from the centre of the myofibre to the periphery, a process defective in certain diseases. A new study reveals that this movement is due to centripetal forces imposed on nuclei by the crosslinking and contraction of myofibrils.
Jonathan N, Rosen, Mary K, Baylies
openaire   +2 more sources

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