Assembly and Dynamics of Myofibrils [PDF]
Journal of Biomedicine and Biotechnology, 2010 We review some of the problems in determining how myofibrils may be assembled and just as importantly how this contractile structure may be renewed by sarcomeric proteins moving between the sarcomere and the cytoplasm.
Jennifer White +4 more
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EXERCISE MYOPATHY: CHANGES IN MYOFIBRILS OF FAST-TWITCH MUSCLE FIBRES
Biology of Sport, 2014 The purpose of the present study was to determine the relationships between the changes of myofibrils in fast-twitch oxidative-glycolytic (type IIA) fibres and fast-twitch glycolytic (type IIB) muscle fibres, protein synthesis and degradation rate in ...
P. Kaasik, M. Umnova, T. Seene
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A Novel Method of Isolating Myofibrils From Primary Cardiomyocyte Culture Suitable for Myofibril Mechanical Study [PDF]
Frontiers in Cardiovascular Medicine, 2019 Myofibril based mechanical studies allow evaluation of sarcomeric protein function. We describe a novel method of obtaining myofibrils from primary cardiomyocyte culture.
Kathleen C. Woulfe +10 more
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Isolation and Mechanical Measurements of Myofibrils from Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes [PDF]
Stem Cell Reports, 2016 Summary: Tension production and contractile properties are poorly characterized aspects of excitation-contraction coupling of human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs).
Josè Manuel Pioner +16 more
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Peptic digestion of beef myofibrils is modified by prior marination [PDF]
Food & Nutrition Research, 2013 Background: Preparatory steps such as seasoning, marination, and cooking may induce changes in meat which affects the ability of the stomach to adequately digest it.
Nash Patel, Simon J. M. Welham
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Myofibrils of skeletal muscle: the activity coefficient of orthophosphate.
, 1997 In the myofibrils of skeletal muscle, at 22°C, pH 7.1 and at the physiological protein osmotic pressure of 1.8 x 105 dynes/cm2, orthophosphate behaves quite ideally, the activity coefficient being 0.85.
MAGRI E. +4 more
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The role of sarcomere length non-uniformities in residual force enhancement of skeletal muscle myofibrils [PDF]
Royal Society Open Science, 2016 The sarcomere length non-uniformity theory (SLNT) is a widely accepted explanation for residual force enhancement (RFE). RFE is the increase in steady-state isometric force following active muscle stretching. The SLNT predicts that active stretching of a
Kaleena Johnston +2 more
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Lbx2regulates formation of myofibrils [PDF]
BMC Developmental Biology, 2009 Skeletal muscle differentiation requires assembly of contractile proteins into organized myofibrils. The Drosophila ladybird homeobox gene (lad) functions in founder cells of the segmental border muscle to promote myoblast fusion and muscle shaping. Tetrapods have two homologous genes (Lbx).
Ochi, Haruki, Westerfield, Monte
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Macroscopic to ultrastructural analyses identify the loss of myofibrils as the primary mediator of ageing- and disuse-induced muscle fibre atrophy. [PDF]
J PhysiolAbstract figure legend Skeletal muscle structure was analysed at three levels in young vs. aged humans, and in young vs. aged mice subjected to unilateral hindlimb immobilization to model disuse. (1) Macroscopic: magnetic resonance imaging of the thigh (human) and wet mass of individual hindlimb muscles (mouse) revealed that both ageing and disuse ...
Sayed RKA +13 more
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The conserved transmembrane proteoglycan Perdido/Kon-tiki is essential for myofibrillogenesis and sarcomeric structure in Drosophila [PDF]
, 2014 M.B. was funded by a Wellcome Trust Senior Investigator Award to P. Lawrence (WT096645MA).Muscle differentiation requires the assembly of high-order structures called myofibrils, composed of sarcomeres.
Estrada, B +8 more
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