Results 11 to 20 of about 16,958 (213)
Current Issues in Molecular Biology, 2023 Mitochondria in mammalian cardiomyocytes display considerable structural heterogeneity, the significance of which is not currently understood. We use electron microscopic tomography to analyze a dataset of 68 mitochondrial subvolumes to look for ...
Raquel A. Adams +6 more
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Assembly and Dynamics of Myofibrils [PDF]
Journal of Biomedicine and Biotechnology, 2010 We review some of the problems in determining how myofibrils may be assembled and just as importantly how this contractile structure may be renewed by sarcomeric proteins moving between the sarcomere and the cytoplasm. We also address in this personal review the recent evidence that indicates that the assembly and dynamics of myofibrils are conserved ...
Sanger, Joseph W. +4 more
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Lbx2regulates formation of myofibrils [PDF]
BMC Developmental Biology, 2009 Skeletal muscle differentiation requires assembly of contractile proteins into organized myofibrils. The Drosophila ladybird homeobox gene (lad) functions in founder cells of the segmental border muscle to promote myoblast fusion and muscle shaping. Tetrapods have two homologous genes (Lbx).
Ochi, Haruki, Westerfield, Monte
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A Supramolecular Polymerization Approach to the Growth of the Myofibril
Frontiers in Chemistry, 2019 Extended linear structures self-assemble by the multi-stage-open-association mechanism of supramolecular polymerization (MSOA). Application of the model requires the identification of a repeating unit, the main-chain supramolecular bond, and the binding ...
Alberto Ciferri, Alvin L. Crumbliss
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Frontiers in Cardiovascular Medicine, 2019 Myofibril based mechanical studies allow evaluation of sarcomeric protein function. We describe a novel method of obtaining myofibrils from primary cardiomyocyte culture.
Kathleen C. Woulfe +10 more
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Mechanobiology of muscle and myofibril morphogenesis
Cells & Development, 2021 Muscles generate forces for animal locomotion. The contractile apparatus of muscles is the sarcomere, a highly regular array of large actin and myosin filaments linked by gigantic titin springs. During muscle development many sarcomeres assemble in series into long periodic myofibrils that mechanically connect the attached skeleton elements.
Luis, Nuno Miguel, Schnorrer, Frank
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Sarcomere formation occurs by the assembly of multiple latent protein complexes. [PDF]
PLoS Genetics, 2010 The stereotyped striation of myofibrils is a conserved feature of muscle organization that is critical to its function. Although most components that constitute the basic myofibrils are well-characterized biochemically and are conserved across the animal
Yanning Rui +2 more
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Effects of high-pressure treatment on the structure and function of myofibrils
Biophysics and Physicobiology, 2021 The effects of high pressure (40–70 MPa) on the structure and function of myofibrils were investigated by high pressure microscopy. When this pressure was applied to myofibrils immersed in relaxing solution, the sarcomere length remained almost unchanged,
Seine A. Shintani
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Complementary Medicine Journal of Faculty of Nursing and Midwifery, 2021 Objective: Cell aging is one of the most important and fundamental step in cellular behavior and reduces muscle mass and myofibrils. This study aims to investigate the effect of resistance exercise along with vitamin C consumption on the expression of ...
Yousef Shirkhani +3 more
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Bio-Protocol, 2020 Protein-protein interactions in Drosophila myofibrils are essential for their function and formation. Bimolecular Fluorescence Complementation (BiFC) is an effective method for studying protein interactions and localization.
Océane Marescal +2 more
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