Results 21 to 30 of about 21,247 (241)

Frequent Manipulation of Resistance Training Variables Promotes Myofibrillar Spacing Changes in Resistance-Trained Individuals

open access: yesFrontiers in Physiology, 2021
We sought to determine if manipulating resistance training (RT) variables differentially altered the expression of select sarcoplasmic and myofibril proteins as well as myofibrillar spacing in myofibers.
Carlton D. Fox   +14 more
doaj   +1 more source

Force per cross-sectional area from molecules to muscles: a general property of biological motors [PDF]

open access: yesRoyal Society Open Science, 2016
We propose to formally extend the notion of specific tension, i.e. force per cross-sectional area—classically used for muscles, to quantify forces in molecular motors exerting various biological functions.
Jean-Pierre Rospars   +1 more
doaj   +1 more source

Drosophila Nesprin-1 Isoforms Differentially Contribute to Muscle Function

open access: yesCells, 2021
Nesprin-1 is a large scaffold protein connecting nuclei to the actin cytoskeleton via its KASH and Calponin Homology domains, respectively. Nesprin-1 disconnection from nuclei results in altered muscle function and myonuclei mispositioning.
Alexandre Rey   +3 more
doaj   +1 more source

Structural Analysis of Mitochondria in Cardiomyocytes: Insights into Bioenergetics and Membrane Remodeling

open access: yesCurrent Issues in Molecular Biology, 2023
Mitochondria in mammalian cardiomyocytes display considerable structural heterogeneity, the significance of which is not currently understood. We use electron microscopic tomography to analyze a dataset of 68 mitochondrial subvolumes to look for ...
Raquel A. Adams   +6 more
doaj   +1 more source

Myofibrils of skeletal muscle: the activity coefficient of orthophosphate.

open access: yes, 1997
In the myofibrils of skeletal muscle, at 22°C, pH 7.1 and at the physiological protein osmotic pressure of 1.8 x 105 dynes/cm2, orthophosphate behaves quite ideally, the activity coefficient being 0.85.
MAGRI E.   +4 more
core   +7 more sources

The role of sarcomere length non-uniformities in residual force enhancement of skeletal muscle myofibrils [PDF]

open access: yesRoyal Society Open Science, 2016
The sarcomere length non-uniformity theory (SLNT) is a widely accepted explanation for residual force enhancement (RFE). RFE is the increase in steady-state isometric force following active muscle stretching. The SLNT predicts that active stretching of a
Kaleena Johnston   +2 more
doaj   +1 more source

Lbx2regulates formation of myofibrils [PDF]

open access: yesBMC Developmental Biology, 2009
Skeletal muscle differentiation requires assembly of contractile proteins into organized myofibrils. The Drosophila ladybird homeobox gene (lad) functions in founder cells of the segmental border muscle to promote myoblast fusion and muscle shaping. Tetrapods have two homologous genes (Lbx).
Ochi, Haruki, Westerfield, Monte
openaire   +2 more sources

The conserved transmembrane proteoglycan Perdido/Kon-tiki is essential for myofibrillogenesis and sarcomeric structure in Drosophila [PDF]

open access: yes, 2014
M.B. was funded by a Wellcome Trust Senior Investigator Award to P. Lawrence (WT096645MA).Muscle differentiation requires the assembly of high-order structures called myofibrils, composed of sarcomeres.
Estrada, B   +3 more
core   +2 more sources

Mechanical characterization of skeletal muscle myofibrils [PDF]

open access: yes, 1996
A new instrument, based on a technique described previously, is presented for studying mechanics of micron-scale preparations of two to three myofibrils or single myofibrils from muscle. Forces in the nanonewton to micronewton range are measurable with 0.
Goldman, Y.E., Friedman, A.L.
core   +1 more source

A Supramolecular Polymerization Approach to the Growth of the Myofibril

open access: yesFrontiers in Chemistry, 2019
Extended linear structures self-assemble by the multi-stage-open-association mechanism of supramolecular polymerization (MSOA). Application of the model requires the identification of a repeating unit, the main-chain supramolecular bond, and the binding ...
Alberto Ciferri, Alvin L. Crumbliss
doaj   +1 more source

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