Results 181 to 190 of about 14,774 (209)
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The actions of thioguanine in Bacillus cereus
Biochemical Pharmacology, 1965Abstract The effects of the guanine analog, 6-thioguanine, have been evaluated in exponentially growing cultures of Bacillus cereus . The drug produced growth inhibition instantly, the duration but not the degree of which was related to the inhibitor concentration.
H G, Mandel, R G, Latimer, M, Riis
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Purine metabolism in thioguanine-resistant glioma cells
Experimental Cell Research, 1976Abstract 6-Thioguanine resistant strains of rat glioma cells were selected spontaneously and after mutagen treatment. Both mutant lines exhibited a severe deficiency of the enzyme hypoxanthine-guanine phosphoribosyltransferase, increased intracellular concentrations of 5-phosphoribosyl-1-pyrophosphate and rate of the early steps of purine ...
S D, Skaper, J E, Seegmiller
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Enumeration of thioguanine-resistant lymphocytes using autoradiography
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis, 1982Strauss and Albertini (1979) proposed a method whereby the frequency of thioguanine-resistant lymphocytes could be measured by an autoradiographic technique and suggested that it would provide a measure of in vivo mutation frequency. A number of variables influencing the method were studied and concentration of thioguanine and duration of assay found ...
A A, Morley +4 more
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[Pancytopenia associated with thioguanine use].
Nederlands tijdschrift voor geneeskunde, 2019Thiopurine drugs, such as thioguanine, mercaptopurine and azathioprine, are used for treating inflammatory bowel disease, such as ulcerative colitis. One must be aware of the serious side effects these drugs can have (e.g. bone marrow depression). A 56-year-old man with ulcerative colitis was treated with mercaptopurine.
Marleen, van der Burg, Martin N, Gerding
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