Results 81 to 90 of about 427,077 (192)

Alteration of Thiol-Disulphide Homeostasis in Fibromyalgia Syndrome

Acta Medica, 2019
Background: Fibromyalgia syndrome (FMS) is an extra-articular rheumatological disease, characterized by widespread pain and somatic symptoms. The etiology has not yet been clarified. Oxidative stress may play an important role in FMS etiology.
Ayca Tuzcu, Rabia Aydogan Baykara, Murat Alışık, Ahmet Omma, Gunseli Karaca Acet, Erdal Dogan, Medine Cumhur Cure, Fatih Duygun, Erkan Cure, Ozcan Erel   +9 more
doaj   +1 more source

N‐acetylcysteine for non‐paracetamol‐induced acute liver failure in children: A systematic review and meta‐analysis

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Non‐surgical treatment of acute liver failure (ALF) is primarily supportive and depends on the underlying cause. While N‐acetylcysteine (NAC) is proven effective in paracetamol‐induced ALF, its potential benefits in non‐paracetamol ALF for paediatric patients remain unclear.
Alise D. E. de Groot, Désanka M. Stoppels, Arno R. Bourgonje, Willemien F. J. Hof, Martin C. J. Kneyber, Daan J. Touw, Henkjan J. Verkade, Paola Mian   +7 more
wiley   +1 more source

Nanomedicine‐driven innovations in postoperative cancer immunotherapy: Remodeling tumor microenvironment and precision delivery strategies

BMEMat, EarlyView.
Nanomedicine‐Driven Strategies for Suppressing Postoperative Tumor Recurrence. This schematic illustrates three pivotal nanomedical strategies that synergistically counteract recurrence by targeting residual disease and the immunosuppressive tumor microenvironment within the surgical cavity.
Lisong Pang, Zhuomin Wang, Zhenhua Jin, Ahmed H. Ghonaim, Hengcheng Zhang, Xinyu You, Jinzhuo Ning, Jiaqing Cao, Yang Liu   +8 more
wiley   +1 more source

Turning Bonding Into Function: The Emerging Role of the Bioactive Selenium─Metal Motif in Toxicology and Medicinal Chemistry

Chemistry – A European Journal, EarlyView.
Balancing Act: Se─M bond serving as the fulcrum of the balance scale to compare the different weight of toxicity and therapeutic effects in biological environment. ABSTRACT The synthesis and characterization of organo‐selenium compounds have attracted considerable interest for decades, driven by the search for efficient catalysts and bioinspired ...
Matteo Filippi, Alessandro Rubbi, Pablo A. Nogara, Giovanni Ribaudo, Vito Lippolis, João B. T. Rocha, Laura Orian   +6 more
wiley   +1 more source

Dynamic thiol/disulfide homeostasis in patients with lichen planus

, 2019
Objective Lichen planus (LP) is an autoimmune inflammatory disease of the mucocutaneous tissue, whose exact pathological course remains unclear.
Alisik, Murat, Aktas, AKIN, Kalkan, GÖKNUR, Emre, SELMA, Baran, Pervin   +4 more
core   +1 more source

The role of thiol/disulfide homeostasis in the differentiation oftransudative and exudative pleural effusion

, 2022
Aim: The dynamic thiol/disulfide homeostasis performs a major role in keeping up the oxidantantioxidant equilibrium. We aimed to find the role of dynamic thiol/disulfide balance in pleuraleffusion transudate-exudate differentiation. This is considered to
Abuzaina, Seray, EREL, Ozcan, Abuzaina, Osama, neselioglu, salim, Hezer, Habibe, HASANOGLU, HATICE CANAN, KARALEZLI, AYSEGÜL   +6 more
core   +1 more source

Dynamic thiol/ disulphide homeostasis in children with attention deficit hyperactivity disorder and its relation with disease subtypes

Psychiatry and Clinical Psychopharmacology, 2021
OBJECTIVE: Attention deficit hyperactivity disorder (ADHD) is common in children and adolescents. Although many factors play a role in the etiopathogenesis of ADHD, recent evidence suggests that the pathophysiology of ADHD may be associated with ...
Sibelnur Avcil, Pinar Uysal, Mucahit Avcil, Murat Alisik, Cemile Bicer   +4 more
doaj  

Reversible Cystine Disulfide Scaffolding Enables Carbonyl Sulfide‐Mediated Intramolecular Peptide Bond Formation via Cyclocystine: Implications for Prebiotic Chemistry

Chemistry – A European Journal, EarlyView.
Cystine is unique among amino acids, in that the disulfide bond can allow intramolecular peptide bond formation. This cyclization offers potential advantages for intramolecular coupling selectivity in prebiotic peptide formation. ABSTRACT Treatment of cystine (the disulfide‐linked dimer of cysteine) with carbonyl sulfide (COS) results in the formation ...
Avinash Vicholous Dass, Arthur Srayeddin, Anthony Rullo, Jonathan Stone, Maikel Rheinstadter, Paul Harrison   +5 more
wiley   +1 more source

Evaluation of thiol/disulfide homeostasis in patients with pityriasis rosea

, 2019
Purpose: Pityriasis rosea (PR) is a common, self-limiting, inflammatory skin disease with an acute onset. The etiology of PR is not yet clearly known but the defect in the oxidation system involved in many papulosquamous skin diseases may play a role ...
Ülfer, Gözde, Yüksel, Mavişe
core   +1 more source

The relationship between serum thiol levels and thiol/disulfide homeostasis in women with tubal ectopic pregnancy

, 2021
© 2021 Elsevier Masson SASObjective: The aim of this study was to investigate the thiol/disulfide homeostasis in tubal ectopic pregnancies in terms of early diagnosis of the disease.
EREL, ÖZCAN, Çekmez, Yasemin, KIRAN, Gürkan, Özer, Nida, Yıldırım Köpük, Şule   +4 more
core   +1 more source