Results 111 to 120 of about 19,795 (176)

Inhibition of cellular thioredoxin reductase by the anticancer prodrug cloretazine

open access: yes, 2008
Sulfonylhydrazines are a class of DNA alkylating drugs which also produce carbamoylating activity in situ. The carbamoylating species is of significance because it has shown to inhibit important thiol-containing enzymes such as glutathione reductase (GR)
Schleicher, Tyler R.
core  

Unveiling the thioredoxin fold: a systematic review and bioinformatic analysis of protein disulfide isomerase and Dsb family proteins. [PDF]

open access: yesFront Bioinform
Cuevas Ortiz D   +8 more
europepmc   +1 more source

Structural basis for substrate recognition and inhibition of thioredoxin glutathione reductase from Schistosoma japonicum: Implications for antiparasitic development. [PDF]

open access: yesPLoS Pathog
Wang S   +18 more
europepmc   +1 more source

The Mechanism and Regulation of Disulfidptosis and Its Role in Disease. [PDF]

open access: yesBiomedicines
Wan Y   +7 more
europepmc   +1 more source

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