Inflammation and RONS Dysregulation by Redox Enzymes as Mechanistic Links in HIV-1-Cancer Comorbidity. [PDF]
Ang CG, Eyunni S, Chaiken IM.
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Inhibition of cellular thioredoxin reductase by the anticancer prodrug cloretazine
Sulfonylhydrazines are a class of DNA alkylating drugs which also produce carbamoylating activity in situ. The carbamoylating species is of significance because it has shown to inhibit important thiol-containing enzymes such as glutathione reductase (GR)
Schleicher, Tyler R.
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Unveiling the thioredoxin fold: a systematic review and bioinformatic analysis of protein disulfide isomerase and Dsb family proteins. [PDF]
Cuevas Ortiz D +8 more
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Disulfidptosis: The metabolic Achilles' heel of SLC7A11-high tumors and why oncology has missed it. [PDF]
Khawar MMH, Naeem I, Safi SU, Khawar M.
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Recent advances in exploring the composition and evolution of the prokaryotic selenoproteome. [PDF]
Zhang Y, Wang S, Li H, Chen X.
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Formation of the intradimer disulfide bond in human calprotectin maintains metal-withholding function and tunes proteolytic susceptibility. [PDF]
Mollo A +4 more
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Structural basis for substrate recognition and inhibition of thioredoxin glutathione reductase from Schistosoma japonicum: Implications for antiparasitic development. [PDF]
Wang S +18 more
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Application of a novel LC-MS-based proteomic workflow for host cell protein monitoring and risk control in biotherapeutics. [PDF]
Yu X +6 more
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The Mechanism and Regulation of Disulfidptosis and Its Role in Disease. [PDF]
Wan Y +7 more
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Systematic determination of disulfide bond reduction potentials reveals a nonequilibrium redox hierarchy in cyanobacteria. [PDF]
Tanaka K, Kondo A, Hasunuma T.
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