Results 31 to 40 of about 162,334 (201)

Measurement of thioredoxin and thioredoxin reductase

, 2001
The thioredoxin system is ubiquitous, providing reducing equivalents to essential biosynthetic enzymes like ribonucleotide reductase. It is essential for cellular redox regulation, control of oxidative stress, and protection against oxidative damage ...
Holmgren, A,, Arnér, ES
core   +1 more source

Thioredoxin Inhibitors Attenuate Platelet Function and Thrombus Formation.

PLoS ONE, 2016
Thioredoxin (Trx) is an oxidoreductase with important physiological function. Imbalances in the NADPH/thioredoxin reductase/thioredoxin system are associated with a number of pathologies, particularly cancer, and a number of clinical trials for ...
Clive Metcalfe, Anjana Ramasubramoni, Giordano Pula, Matthew T Harper, Stuart J Mundell, Carmen H Coxon   +5 more
doaj   +1 more source

Western blots of cytosolic Thioredoxin and Thioredoxin reductase.

, 2016
Representative western blots used for the protein estimations of cytosolic thioredoxin (A) and cytosolic thioredoxin reductase (B).
Galina Zeltcer (2890028), Mordechai Chevion (119370), Benjamin Drenger (2890031), Hilbert Grievink (2890025), Eduard Berenshtein (119363)   +4 more
core   +1 more source

Oligo-Carrageenan Kappa-Induced Reducing Redox Status and Activation of TRR/TRX System Increase the Level of Indole-3-acetic Acid, Gibberellin A3 and trans-Zeatin in Eucalyptus globulus Trees

Molecules, 2014
Eucalyptus globulus trees treated with oligo-carrageenan (OC) kappa showed an increase in NADPH, ascorbate and glutathione levels and activation of the thioredoxin reductase (TRR)/thioredoxin (TRX) system which enhance photosynthesis, basal metabolism ...
Alberto González, Rodrigo A. Contreras, Gustavo Zúiga, Alejandra Moenne   +3 more
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

The Barley Grain Thioredoxin System – an Update

Frontiers in Plant Science, 2013
Thioredoxin reduces disulfide bonds and play numerous important functions in plants. In cereal seeds, cytosolic h-type thioredoxin facilitates the release of energy reserves during the germination process and is recycled by NADPH-dependent thioredoxin ...
Per eHägglund, Olof eBjörnberg, Nicolas eNavrot, Johanne eMørch Jensen, Kenji eMaeda, Kristine eKirkensgaard, Azar eShahpiri, Abida eSultan, Jakob eBunkenborg, Frank eGubler, José Maria Barrero, Anette eHenriksen, Christine eFinnie, Birte eSvensson   +13 more
doaj   +1 more source

Synthesis and Biological Activity of Prodrug Inhibitors of the Thioredoxin-Thioredoxin Reductase System.

, 2005
A series of palmarumycin prodrugs and water-soluble analogs has been synthesized and assayed for inhibition of the thioredoxin-thioredoxin reductase system.
Lynch, Stephen M, Englund, Erikah E, Wipf, Peter, Powis, Garth, Birmingham, Anne   +4 more
core   +1 more source

GaSex Nanoparticles Modulate Neutrophil Function and Mitigate NET‐Driven Osteogenic Impairment in Osteomyelitis Therapy

Advanced Materials, EarlyView.
Neutrophil extracellular traps (NETs) emerge as a critical repair‐limiting factor in osteomyelitis, driving osteoblast mitochondrial dysfunction and excessive PINK1/Parkin‐mediated mitophagy. Gallium–selenium nanoparticles (GaSex) scavenge reactive oxygen species, redirect neutrophils from NETosis toward bactericidal phagocytosis, eliminate methicillin‐
Kai Ye, Xuanzhe Liu, Zifan Pei, Chenyi Jiang, Xiaofen Zhang, Lin Lin, Qihang Fang, Binyu Chen, Longxiang Shen, Liang Cheng, Peng Ding, Xianyou Zheng   +11 more
wiley   +1 more source

Interaction of recombinant form of NADPH-dependent thioredoxin reductase from rice with thioredoxin from two plant and bacterial sources [PDF]

مجله بیوتکنولوژی کشاورزی, 2014
Maintaining redox homeostasis in the cell is critical for different cellular metabolisms and signal transduction pathways. In plants different molecular mechanisms are involved in maintaining cellular redox homeostasis.
Hadiyeh Eslam Panah, Azar Shah Piri, Ehsan Sheykholeslam   +2 more
doaj   +1 more source

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source