Results 171 to 180 of about 6,985 (261)

Obstructive Sleep Apnea: Epidemiology, Pathophysiology, Complications, Diagnosis, Management, and Emerging Fibrosis‐Linked Remodeling

open access: yesMedComm, Volume 7, Issue 8, August 2026.
Obstructive sleep apnea (OSA) is characterized by recurrent upper‐airway collapse, which generates key nocturnal stressors including intermittent hypoxia, sleep fragmentation, intrathoracic pressure stress, and sympathetic activation. These physiological disturbances converge on shared biological mechanisms, including oxidative stress, inflammation ...
Nhi Ho Thi Thuy   +8 more
wiley   +1 more source

Macrophage: Biological Functions, Diseases, and Therapeutic Targets

open access: yesMedComm, Volume 7, Issue 8, August 2026.
Macrophages are sentinel innate immune cells that arise from embryonic precursors and bone marrow monocytes, displaying a functional continuum that transcends the classical M1 (pro‐inflammatory)/M2 (anti‐inflammatory) dichotomy. Under homeostatic conditions, balanced M1/M2 polarization preserves tissue integrity by coordinating immune surveillance ...
Bihang Sun   +4 more
wiley   +1 more source

Pathogenesis of Tuberculosis: Interplay Between Host Antituberculosis Immunity and Immune Evasion Strategies of Mycobacterium Tuberculosis

open access: yesMedComm, Volume 7, Issue 8, August 2026.
Mycobacterium tuberculosis–host interactions and infection outcomes. Following initial infection, alveolar macrophages phagocytose the pathogen, prompting the recruitment of innate immune cells including neutrophils, NK cells, and interstitial macrophages.
Xiaojuan Zhang   +3 more
wiley   +1 more source

Virus Propagation Linked to Exceedingly Rare Gene-Expression Errors: A Single-Molecule Microscopy Demonstration. [PDF]

open access: yesACS Chem Biol
Luzón-Hidalgo R   +7 more
europepmc   +1 more source

Elevated Expression of Selenoprotein Synthesis Enzyme SEPHS2 Driven by ATF4 Promotes the Resistance to Ferroptosis in Prostate Cancer

open access: yesMedComm, Volume 7, Issue 8, August 2026.
Under the treatment of ferroptosis inducers, the expression of SEPHS2 is upregulated, driven by ATF4, to increase the biosynthesis of selenoproteins (e.g., GPX4) to promote resistance to ferroptosis. ABSTRACT While it has been reported that antioxidant selenoproteins are crucial for anti‐ferroptosis in tumors, it remains unclear whether and how ...
Shijia Bao   +9 more
wiley   +1 more source

Ancestral Chaperonins Provide the First Structural Glimpse into Early Multimeric Protein Evolution. [PDF]

open access: yesMol Biol Evol
Severino R   +8 more
europepmc   +1 more source

Radiobiology studies of gold nanoparticle‐enhanced radiosensitization in proton therapy

open access: yesMedical Physics, Volume 53, Issue 8, August 2026.
Abstract Background Approximately 50%$\%$ of newly diagnosed cancer patients worldwide receive radiotherapy, most commonly with X‐rays. Proton therapy has emerged as a promising alternative, offering complementary advantages over conventional X‐rays due to its highly localized energy deposition at the Bragg peak, thereby reducing radiation exposure to ...
N. Fuster‐Martínez   +13 more
wiley   +1 more source

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